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New insights regarding challenges in rare disease diagnosis, drug approval, and patient access

Value in Health, the official journal of ISPOR, announced today the publication of a series of articles offering important insight regarding the challenges in rare disease diagnosis, drug approval, and patient access.

17 May 2018

FutureNeuro and GreenLight Medicines team up to develop cannabis-based treatments for epilepsies

A new partnership between FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological diseases based at RCSI and GreenLight Medicines, an indigenous Irish biopharmaceutical company has been formed to develop new cannabis-based treatments for drug-resistant epilepsies, and in particular, childhood epilepsies.

17 May 2018

Study identifies factors associated with substance use treatment engagement

About 22 million Americans are substance dependent (illicit drugs and alcohol), which interferes with routine life and requires treatment. Yet, only 2.5 million of these Americans participate in treatment services.

17 May 2018

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults.

17 May 2018

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.

16 May 2018

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

In a recent study published in the Journal of Clinical Investigation, Mayo Clinic researchers identified that an FDA drug approved for myelodysplastic syndrome may be useful to treat triple-negative breast cancer, which is one of the most aggressive and lethal types of breast cancer.

16 May 2018

Researchers are developing new algorithms to predict protein structure

With protein design dating back to the mid-1970s, today’s scientists have access to a huge amount of information and tools that they can use to create proteins – such abundant, diverse material, in fact, that the data they need may be hard to find.

16 May 2018

Emulate partners with AstraZeneca to accelerate development of Organs-on-Chips technology

Emulate, Inc. has formed a collaborative partnership with AstraZeneca's Innovative Medicines and Early Development Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.

16 May 2018

Study: Drug used to treat blood loss may be beneficial for some stroke patients

Patients with stroke caused by bleeding on the brain may benefit from receiving a drug currently used to treat blood loss from major trauma and bleeding after childbirth, an international trial has revealed.

16 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Reversing an overdose isn’t complicated, but getting the antidote can be

A few months ago, Kourtnaye Sturgeon helped save someone’s life. She was driving in downtown Indianapolis when she saw people gathered around a car on the side of the road. Sturgeon pulled over, and a man told her there was nothing she could do: Two men had overdosed on opioids and appeared to be dead.

16 May 2018

MDMA appears to help in treating PTSD patients

When lasting trauma is caused by callous acts of violence, the key to recovery can be making meaning out of meaninglessness.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Study finds distinct exhausted T cells that could have implications for fighting different diseases

The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate

16 May 2018

National trial shows how high-tech strategies may change the field of mental health

A national research trial initiated by UT Southwestern in 2012 is generating the first set of results this year that provides an early glimpse into how such high-tech strategies may change the field of mental health.

16 May 2018

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

Revealing all the steps required to activate an enzyme called a protein kinase may identify new ways to target cancer, according to new University of Arizona-led research.

16 May 2018

First epoetin alfa biosimilar receives FDA approval to treat certain types of anemia

The U.S. Food and Drug Administration today approved Retacrit (epoetin alfa-epbx) as a biosimilar to Epogen/Procrit (epoetin alfa) for the treatment of anemia caused by chronic kidney disease, chemotherapy, or use of zidovudine in patients with HIV infection.

16 May 2018

Majority of prescription drug commercials focus on lifestyle improvements, study finds

Prescription drug commercials are getting longer and providing less factual information. A study published in the Annals of Family Medicine finds that the majority of these ads focus on lifestyle improvements made post-medication rather than side-effects and the negative emotions associated with certain health issues.

15 May 2018

Study lays foundation for treating drug, alcohol addicts with noninvasive brain stimulation

In a study investigating the use of transcranial magnetic stimulation for drug addiction, researchers at Medical University of South Carolina are the first to demonstrate that the noninvasive brain stimulation technique can dampen brain activity in response to drug cues in chronic alcohol users and chronic cocaine users.

15 May 2018

Drug-resistant staph infections found to be deadly, but less costly

Staph infections, whether MRSA (resistant to methicillin) or susceptible, are important and deadly. Drug-resistant staph infections continue to be deadlier than those that are not resistant and treatable with traditional antibiotics, but treatment costs surprisingly are the same or slightly less, a new national analysis shows.

15 May 2018

Drugs News and Research

New insights regarding challenges in rare disease diagnosis, drug approval, and patient access

FutureNeuro and GreenLight Medicines team up to develop cannabis-based treatments for epilepsies

Study identifies factors associated with substance use treatment engagement

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Mayo Clinic researchers identify new possible treatment choice for triple negative breast cancer

Researchers are developing new algorithms to predict protein structure

Emulate partners with AstraZeneca to accelerate development of Organs-on-Chips technology

Study: Drug used to treat blood loss may be beneficial for some stroke patients

New study could have important implications for cellular aging

Reversing an overdose isn’t complicated, but getting the antidote can be

MDMA appears to help in treating PTSD patients

Researchers demonstrate new strategy for stimulating autophagy

Study finds distinct exhausted T cells that could have implications for fighting different diseases

National trial shows how high-tech strategies may change the field of mental health

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

First epoetin alfa biosimilar receives FDA approval to treat certain types of anemia

Majority of prescription drug commercials focus on lifestyle improvements, study finds

Study lays foundation for treating drug, alcohol addicts with noninvasive brain stimulation

Drug-resistant staph infections found to be deadly, but less costly

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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