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Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

Researchers build 3-D printer that offers sweet solution to making detailed structures

University of Illinois engineers built a 3-D printer that offers a sweet solution to making detailed structures that commercial 3-D printers can't: Rather than a layer-upon-layer solid shell, it produces a delicate network of thin ribbons of hardened isomalt, the type of sugar alcohol used to make throat lozenges.

25 May 2018

Lunaphore and Vitro announce partnership to develop ISH protocols for RNA, DNA targets

Lunaphore Technologies SA, a next generation tissue diagnostics company, and Vitro SA, a manufacturer in the field of Pathology and Biomedical Research, announce today a collaboration agreement to develop In Situ Hybridization protocols for RNA and DNA targets in tissue using reagents provided by Vitro on Lunaphore’s rapid autostaining platform.

25 May 2018

BMC receives $13.5 million award to test methods for delivering childhood anxiety treatment

Boston Medical Center has been approved for a $13.5 million award by the Patient-Centered Outcomes Research Institute to test the efficacy of two different methods of delivering cognitive behavioral therapy - face to face or online - to children with anxiety.

25 May 2018

Researchers find novel ways to improve participation in clinical research

Videos and creative uses of other visuals provide a novel way to obtain informed consent during clinical trials to improve participants' understanding and retention of trial information, according to a study by Nemours Children's Health System presented at the American Thoracic Society (ATS) Annual Conference.

25 May 2018

$2.3 million NIH grant to support new project on oxytocin neurons and social behavior

A team of Penn State researchers is planning to create a new map of the brain that will establish a neural circuit diagram of oxytocin, a compound often associated with affection and emotional behavior. Researchers hope the map will give them insight into how oxytocin in the brain drives social behavior.

24 May 2018

International researchers succeed in stopping growth of mesothelioma in model animals

An international team led by researchers from the Technion-Israel Institute of Technology and NYU Langone Health have succeeded in stopping the growth of mesothelioma in model animals by inhibiting the heparanase enzyme.

24 May 2018

Zika detection breakthrough by University of Queensland

A cheap and effective tool that could save lives by helping health authorities target mosquitos infected with Zika virus has been developed by researchers from the University of Queensland and colleagues in Brazil.

23 May 2018

Skin responsible for uptake of cancer-causing compounds during barbecuing than lungs

With summer coming, it's only a matter of time before the smells and tastes of barbecued foods dominate the neighborhood. But there's a downside to grilling that can literally get under your skin.

23 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

Comparative Analysis of a Complex Monoclonal Antibody

Postnova Analytics has published a new poster that compares the suitability of Electrical Asymmetrical Flow Field Flow Fractionation (EAF4) and Size Exclusion Chromatography (SEC) for determining the physicochemical and biophysical attributes of monoclonal antibodies.

From Postnova Analytics 23 May 2018

Investigational technology could increase donor organ supply for lung transplants

As many as 80 percent of lungs from organ donors are not used, either because they are not in good enough condition to transplant, or there are doubts about their quality and there is no way to verify their condition.

23 May 2018

New technology could make prosthetic use more intuitive and reliable

Researchers have developed new technology for decoding neuromuscular signals to control powered, prosthetic wrists and hands. The work relies on computer models that closely mimic the behavior of the natural structures in the forearm, wrist and hand.

23 May 2018

Study: Subtle hearing deficits can change the brains of young people

Cranking up your headphones or scrambling for a front-row spot at rock shows could be damaging more than your hearing.

23 May 2018

Health and diagnostics to soon be digitalized with advent of AI

Despite the fact that health in general globally is facing several challenges including antibiotic resistance, lack of accessible and affordable health care, rise of chronic and untreatable diseases such as dementia, there is a ray of hope in the advent of technology in healthcare.

22 May 2018

Current architecture of knowledge generation in healthcare needs change

ISPOR, the professional society for health economics and outcomes research, held a special "Spotlight Session" this afternoon entitled, "Reinventing the Future of Knowledge Generation in Healthcare," at its ISPOR 2018 conference in Baltimore, MD, USA.

22 May 2018

Specific patterns of fat distribution linked to metabolic disease, shows study

Specific patterns of fat distribution are linked to the presence of Coronary Heart Disease and Type 2 Diabetes, according to a new study published in Obesity.

22 May 2018

New way of grouping atoms could herald novel materials, drugs and computers

Scientists have found a new way of joining groups of atoms together into shape-changing molecules - opening up the possibility of a new area of chemistry and the development of countless new drugs, microelectronics and materials with novel characteristics.

22 May 2018

Ingesting blue dye tablet during colonoscopy aids in detecting difficult-to-see polyps

Ingestion of a blue dye tablet during bowel prep for colonoscopy could be a significant advance in the early detection of colorectal cancer.

22 May 2018

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

A non-surgical procedure, called percutaneous coronary intervention, along with prescribed medication, is better than medication alone as initial treatment for people who have the most common form of heart disease, suggests an analysis of an international clinical trial co-led by St. Michael's Hospital.

22 May 2018

Technology News and Research

Researchers reveal potent new mechanism of action for treatment of IBD

Researchers build 3-D printer that offers sweet solution to making detailed structures

Lunaphore and Vitro announce partnership to develop ISH protocols for RNA, DNA targets

BMC receives $13.5 million award to test methods for delivering childhood anxiety treatment

Researchers find novel ways to improve participation in clinical research

$2.3 million NIH grant to support new project on oxytocin neurons and social behavior

International researchers succeed in stopping growth of mesothelioma in model animals

Zika detection breakthrough by University of Queensland

Skin responsible for uptake of cancer-causing compounds during barbecuing than lungs

Mapping the Genes Responsible for Pluripotency

Comparative Analysis of a Complex Monoclonal Antibody

Investigational technology could increase donor organ supply for lung transplants

New technology could make prosthetic use more intuitive and reliable

Study: Subtle hearing deficits can change the brains of young people

Health and diagnostics to soon be digitalized with advent of AI

Current architecture of knowledge generation in healthcare needs change

Specific patterns of fat distribution linked to metabolic disease, shows study

New way of grouping atoms could herald novel materials, drugs and computers

Ingesting blue dye tablet during colonoscopy aids in detecting difficult-to-see polyps

PCI along with prescribed drugs better than medication alone for treating for people with heart disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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