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Why the drugmaker that paid Trump’s lawyer $1.2 million is so worried

President Donald Trump didn't mention Novartis or other drugmakers by name last year when he said the industry is "getting away with murder."

11 May 2018

Study uncovers new circuit that fine tunes brain's decision to hide or confront threats

In a study of mice, National Institutes of Health-funded researchers describe a new circuit involved in fine-tuning the brain's decision either to hide or confront threats.

11 May 2018

Oral antibiotic use may increase risk of developing kidney stones, shows study

Pediatric researchers have found that children and adults treated with some oral antibiotics have a significantly higher risk of developing kidney stones.

11 May 2018

Good bacteria is bad news for atherosclerosis

Researchers have discovered that the microbiome heavily influences hardening of the arteries (atherosclerosis), a known risk factor for cardiovascular disease.

11 May 2018

Addressing Antimicrobial Resistance Through Industry

Antimicrobial resistance is currently one of the biggest health threats in the world. Gary Cohen and Steve Conly discuss the role of Becton, Dickinson & Co and other organizations in the private sector in combating the spread of resistance.

11 May 2018

Scientists discover a mechanism through which HIV determines the fate and function of cells

A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell.

11 May 2018

People with atrial fibrillation should continue to be treated even if heart rhythm returns to normal

Patients with an abnormal heart rhythm that can leave them at a higher risk of suffering from stroke still need treatment even after their heart rhythm seems to have returned to normal, say researchers at the University of Birmingham.

11 May 2018

Researchers identify serotonin receptor that could be targeted to boost memory

In a breakthrough that could one day help individuals with cognitive impairment, researchers at Columbia University Irving Medical Center identified a specific receptor related to the neurotransmitter serotonin that could be targeted with drugs to boost memory.

11 May 2018

Podcast: KHN’s ‘What the Health?’ The politics of rising premiums and menu labeling

Proposed insurance premium increases unveiled in Maryland and Virginia officially marked the start of finger-pointing on Capitol Hill this week, as Democrats and Republicans blamed each other for the dysfunction of the individual insurance market under the Affordable Care Act.

10 May 2018

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Cancer cells that develop resistance to drugs, pay a price for this, by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically.

10 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Aravive Biologics, Inc. announced today that the company has demonstrated clinical proof-of-mechanism for AVB-S6-500 in neutralizing GAS6, based on analysis of the single ascending dose portion of the ongoing Phase 1 study.

10 May 2018

Midterm elections are shaping up to be a referendum on Trumpism

Voters looking toward the midterm elections are more motivated by a candidate's stance on President Donald Trump than on any specific policy question.

10 May 2018

New model based on combination of GANs with reinforcement learning for drug discovery

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".

10 May 2018

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

10 May 2018

Scientists successfully graft neural precursor cells into spinal cords of syngeneic pigs with no immunosuppression

A major hurdle to using neural stem cells derived from genetically different donors to replace damaged or destroyed tissues, such as in a spinal cord injury, has been the persistent rejection of the introduced material, necessitating the use of complex drugs and techniques to suppress the host's immune response.

10 May 2018

Scientific understanding of PSTD points to new treatment and prevention strategies

Recent advances in scientific understanding of how posttraumatic stress disorder develops and persists may lead to more effective treatment and even prevention of this debilitating disorder, according to the May/June special issue of Harvard Review of Psychiatry, published by Wolters Kluwer.

10 May 2018

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

Scientists at The Scripps Research Institute have devised what they call a "neuronal cookbook" for turning skin cells into different types of neurons.

10 May 2018

New lab-on-a-chip device shows promise in treating retinal diseases

Houston Methodist researchers developed a new lab-on-a-chip technology that could quickly screen possible drugs to repair damaged neuron and retinal connections, like what is seen in people with macular degeneration or who've had too much exposure to the glare of electronic screens.

10 May 2018

Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Drugs News and Research

Why the drugmaker that paid Trump’s lawyer $1.2 million is so worried

Study uncovers new circuit that fine tunes brain's decision to hide or confront threats

Oral antibiotic use may increase risk of developing kidney stones, shows study

Good bacteria is bad news for atherosclerosis

Addressing Antimicrobial Resistance Through Industry

Scientists discover a mechanism through which HIV determines the fate and function of cells

People with atrial fibrillation should continue to be treated even if heart rhythm returns to normal

Researchers identify serotonin receptor that could be targeted to boost memory

Podcast: KHN’s ‘What the Health?’ The politics of rising premiums and menu labeling

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Midterm elections are shaping up to be a referendum on Trumpism

New model based on combination of GANs with reinforcement learning for drug discovery

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists successfully graft neural precursor cells into spinal cords of syngeneic pigs with no immunosuppression

Scientific understanding of PSTD points to new treatment and prevention strategies

Researchers devise neuronal cookbook for turning skin cells into different types of neurons

New lab-on-a-chip device shows promise in treating retinal diseases

Study discovers genetic variations that increase heart attack risk for statin patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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