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Texas Biomed awarded $1 million to evaluate MAb therapeutics for COVID-19

Texas Biomedical Research Institute in San Antonio, Texas, was awarded $1 million from the Bill & Melinda Gates Foundation to test the efficacy of human monoclonal antibodies (MAbs) for the treatment of SARS-CoV-2 infection.

19 Nov 2020

Carrageenan-based composite nasal spray may help prevent SARS-CoV-2 infection

A team of researchers at the University of Birmingham in the United Kingdom formulated a spray that contains polysaccharides known for their mucoadhesive antiviral properties for prophylaxis against SARS-CoV-2 infection.

19 Nov 2020

KHN’s ‘What the Health?’: What would Dr. Fauci do?

Since the mid-1980s, whenever there's been a public health crisis, America — and six U.S. presidents — have turned to Dr. Anthony Fauci.

19 Nov 2020

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Organ and stem cell transplants are proven and frequently used methods in everyday modern clinical practice. However, even when performed regularly in specialized centers, some patients still experience a number of serious complications afterward.

19 Nov 2020

"Escape mutations" could help SARS-CoV-2 evade immune attack

Researchers in the United States have identified mutations within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that can reduce antibody binding to the virus, potentially mediating its escape from immune attack.

18 Nov 2020

UC researcher receives $443,000 NIH grant to study antiviral drugs

University of Cincinnati pharmaceutical sciences researcher Bingfang Yan, DVM, has received a $443,000 grant from the National Institutes of Health to study how common medicines against viral infections are genetically impacted for therapeutic effectiveness and safety through metabolic conversions in the body.

18 Nov 2020

Conservation of tropical peatlands could reduce the likelihood of new zoonotic diseases

Conservation of tropical peatlands could reduce the impacts of the COVID-19 pandemic and the likelihood of new diseases jumping from animals to humans, researchers say.

17 Nov 2020

Widespread COVID-19 testing may be possible with new dried blood tests

Researchers have developed dried blood spot sample testing that could be instrumental in preventing the spread of SARS- CoV-2.

17 Nov 2020

Researchers report encouraging results from in vitro combination therapy against COVID-19

Researchers at Karolinska Institutet in Sweden report promising results from an in vitro combination therapy against COVID-19.

17 Nov 2020

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

The discovery of a potential "Achilles heel" in Nef, the protein that is crucial to HIV virulence and its capacity to trigger AIDS, paves the way for the development of a new class of drugs against the virus.

17 Nov 2020

Asymptomatic individuals mount polyfunctional antibody response to SARS-CoV-2

Researchers in France have conducted a study showing that people who are asymptomatic following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – elicit a polyfunctional antibody response to the virus.

16 Nov 2020

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

The first randomized phase 3 clinical trial ever to be conducted in patients with advanced cancer of the anal canal is now open and enrolling patients.

16 Nov 2020

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

The study, which appeared in the Journal of Taibah University Medical Sciences, shows that the SARS-CoV-2 may behave akin to the CNS pathogenic mechanism of JEV and HIV during the early stages of infection.

15 Nov 2020

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

A recent study published in the International Journal of Infectious Diseases has explained the lower prevalence of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa compared to that in the US, Europe, and Asia.

15 Nov 2020

MIT researchers unravel the molecular structure of key coronavirus protein

MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus's ability to replicate itself and stimulate the host cell's inflammation response.

12 Nov 2020

COVID-19 treatments for people with early infection should be prioritized

COVID-19 treatments for people with early infection are needed urgently, according to a JAMA Viewpoint article by National Institute of Allergy and Infectious Diseases (NIAID) Director Anthony S. Fauci, M.D., and colleagues.

11 Nov 2020

Study: SphK2 enzyme regulates immune cell responses during viral infection

Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections.

11 Nov 2020

Cabotegravir highly effective in preventing HIV among women

UNAIDS has been strongly encouraged by groundbreaking new study results showing that the antiretroviral medicine cabotegravir administered by an injection every two months – prevents HIV among women.

10 Nov 2020

Promising new antivirals target arboviruses and SARS-CoV-2: Nodosome inhibitors

A new study describes two promising small molecules that inhibit a host cell factor, called nucleotide binding oligomerization domain-containing protein 2 (NOD2), that inhibits the replication and spread of many arboviruses. This could lead to the development of broad-spectrum antivirals. The study's findings have been published on the preprint server bioRxiv*.

10 Nov 2020

Trump’s anti-abortion zeal shook fragile health systems around the world

In Ethiopia, health clinics for teenagers once supported by U.S. foreign aid closed down. In Kenya, a decades-long effort to integrate HIV testing and family planning unraveled.

10 Nov 2020