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Ingestible capsule can monitor vital signs from within the patient's GI tract

Diagnosing sleep disorders such as sleep apnea usually requires a patient to spend the night in a sleep lab, hooked up to a variety of sensors and monitors.

17 Nov 2023

Study suggests optimal blood pressure targets for Asian adults with type 2 diabetes

Keeping blood pressure in check could save lives among Asian adults with type 2 diabetes, suggests a sizable new study of more than 80,000 patients in Singapore. But how low should it go?

16 Nov 2023

Long-term monitoring of gene therapy patients crucial for safety, study says

Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new insights into processes happening in the body after treatment.

16 Nov 2023

Air filtration systems do not reduce risk of viral infections, study finds

Air filtration systems do not reduce the risk of picking up viral infections, according to new research from the University of East Anglia.

16 Nov 2023

Compensation is key to fixing primary care shortage

Money talks. The United States faces a serious shortage of primary care physicians for many reasons, but one, in particular, is inescapable: compensation.

16 Nov 2023

Shrinkage in the brain's hippocampus area associated with cognitive decline

With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder.

15 Nov 2023

Breast cancer survivors use peer-recommended or self-discovered techniques to improve sexual functioning

A third of users on a popular breast cancer support forum describe using peer-recommended or self-discovered techniques to improve sexual functioning, according to a study published November 15, 2023 in the open-access journal PLOS ONE by Christiana von Hippel from the Dana-Farber Cancer Institute and Harvard T.H. Chan School of Public Health, USA, and colleagues.

15 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.

15 Nov 2023

Sir Peter Barnes on World COPD Day: Awareness, Advances, and the Road Ahead

In this interview, we delve into the remarkable journey of Professor Sir Peter Barnes, a leading figure in respiratory medicine.

15 Nov 2023

Gene therapy for rare diseases: A decade of progress and remaining challenges

A new review article in the peer-reviewed journal Human Gene Therapy summarizes the significant milestones in the development of gene therapy medicinal products that have facilitated the treatment of a significant number of rare diseases.

14 Nov 2023

New app aims to ease burden on caregivers of dementia patients

With the number of Americans living with dementia expected to more than double to 13.8 million by 2060, two Regenstrief Institute research scientists and Indiana University professors have created an app to ease the burden on caregivers.

14 Nov 2023

IU researchers receive $5 million grant to improve care for adolescents with opioid use disorder

IU School of Medicine researchers are taking steps to improve the accessibility and quality of care for adolescents experiencing opioid use disorder (OUD) and other substance use disorders (SUDs), thanks to a new $5 million grant from the National Institute of Health's Helping to End Addiction Long-Term (HEAL) Initiative.

14 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Abelacimab significantly reduces bleeding risk in atrial fibrillation patients with stroke risk

An experimental anti-clotting medication, abelacimab, significantly reduced bleeding among people with atrial fibrillation (or AFib) who were at risk of stroke, according to results of the AZALEA-TIMI 71 trial, presented today as late-breaking science at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

A National Institutes of Health-supported study found that the type of transfusion approach used to support adults who developed anemia after a heart attack did not make a significant difference in their likelihood of having another heart attack or dying within 30 days.

13 Nov 2023

Changing environment can have long-term, significant effects on the brain

Changes in a person's environment can have long-term, significant effects on the brain, whether it's the inhalation of wildfire smoke or the experience of childhood trauma.

13 Nov 2023

Medical School News and Research

Ingestible capsule can monitor vital signs from within the patient's GI tract

Study suggests optimal blood pressure targets for Asian adults with type 2 diabetes

Long-term monitoring of gene therapy patients crucial for safety, study says

Air filtration systems do not reduce risk of viral infections, study finds

Compensation is key to fixing primary care shortage

Shrinkage in the brain's hippocampus area associated with cognitive decline

Breast cancer survivors use peer-recommended or self-discovered techniques to improve sexual functioning

Study sheds new light on key cellular processes involved in Parkinson's disease progression

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

Sir Peter Barnes on World COPD Day: Awareness, Advances, and the Road Ahead

Gene therapy for rare diseases: A decade of progress and remaining challenges

New app aims to ease burden on caregivers of dementia patients

IU researchers receive $5 million grant to improve care for adolescents with opioid use disorder

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Abelacimab significantly reduces bleeding risk in atrial fibrillation patients with stroke risk

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

Changing environment can have long-term, significant effects on the brain

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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