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Researchers define new treatment for potentially fatal lung disease in patients with CVID

A team of researchers at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute defined a new treatment for a potentially fatal lung disease in patients with a primary immunodeficiency known as common variable immunodeficiency (CVID).

1 Sep 2012

French data highlight women under 60 at risk for heart disease

An analysis of four French registries has shown a dramatic drop in ST-segment-elevation myocardial infarction mortality from 1995 to 2010, accompanied by a significant change in patient characteristics.

31 Aug 2012

Tunes and T-shirts for cardiac rehabilitation

Two studies presented at the European Society of Cardiology Congress in Munich, Germany, showed how researchers are developing innovative approaches to help patients get the most out of cardiac rehabilitation.

31 Aug 2012

Less than half of U.S. schools address pandemic preparedness in their school plan

Less than half of U.S. schools address pandemic preparedness in their school plan, and only 40 percent have updated their school plan since the 2009 H1N1 pandemic, according to a study published in the September issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

31 Aug 2012

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Ironwood Pharmaceuticals, Inc. and Forest Laboratories, Inc. announced today that LINZESS (linaclotide) was approved by the U.S. Food and Drug Administration (FDA) as a once-daily treatment for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC).

31 Aug 2012

Sosei’s QVA149 Phase III study on COPD meets primary endpoint

Sosei Group Corporation confirms the information released today by Novartis that results from the fifth QVA149 (indacaterol maleate / glycopyrronium bromide) Phase III study, SPARK, met its primary endpoint of a reduced rate of moderate-to-severe COPD exacerbations compared to glycopyrronium bromide.

31 Aug 2012

Physical, verbal reminders could improve preoperative preparation

Patients may be unable to recall much of the preoperative information they are given by anesthesiologists, suggesting the need for reminders such as printed instructions, and telephone calls the night before their procedure is scheduled, says a US research team.

30 Aug 2012

Emergency readmission after endoscopy linked to mortality risk

The risk for mortality is significantly increased among patients who are readmitted urgently following endoscopy, compared with other endoscopy patients, a UK study shows.

30 Aug 2012

Anastomotic leakage does not increase rectal cancer recurrence risk

Incidence of clinical anastomotic leak after anterior resection for patients with rectal adenocarcinoma does not increase the risk for local disease recurrence, despite previous studies indicating the opposite, report US researchers.

30 Aug 2012

Janssen receives FDA Priority Review for ZYTIGA sNDA to treat mCRPC

Janssen Research & Development, LLC, announced today that the U.S. Food and Drug Administration (FDA) has granted Priority Review to the supplemental New Drug Application (sNDA) for ZYTIGA (abiraterone acetate) administered in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy.

30 Aug 2012

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

The U.S. Food and Drug Administration today approved Afinitor Disperz (everolimus tablets for oral suspension), a new pediatric dosage form of the anti-cancer drug Afinitor (everolimus) used to treat a rare brain tumor called subependymal giant cell astrocytoma.

30 Aug 2012

Vitamin to the rescue in fight with ‘superbugs’

High doses of vitamin B3 may help fight against so called “superbugs” such as methicillin-resistant Staphylococcus aureus, show study results.

29 Aug 2012

Physicians’ emotional, institutional barriers prolong medical futility at end of life

The most common reasons that clinicians give to explain medically futile treatment at the end of life are emotional difficulties, such as a fear of talking about death, and institutional barriers, such as hospital departments expecting them to “do everything possible,” report German researchers.

29 Aug 2012

AstraZeneca’s ticagrelor receives Class I recommendation from ESC

AstraZeneca today announced that ticagrelor, an oral antiplatelet medicine, received a Class I recommendation from the European Society of Cardiology (ESC) in the revised "Guidelines on the Management of Acute Myocardial Infarction in Patients Presenting with Persistent ST-Segment Elevation (STEMI)" guidelines.

29 Aug 2012

New Wilderness Medical Society guidelines for prevention and treatment of lightning injuries

About 24,000 people are killed by lightning every year, with about 10 times as many people injured. The Wilderness Medical Society has issued important new practice guidelines for precautions that can lower the likelihood of being killed or injured and recommendations for effective medical treatments post-strike.

29 Aug 2012

NUI Galway project hopes to deliver cost effective tool for rapid diagnosis of pneumonia

Researchers at NUI Galway are involved in a new European project which hopes to deliver a cost effective tool for the speedy diagnosis of infections such as pneumonia. The test would reduce diagnosis time from days to hours, so that the appropriate treatments can be administered as early as possible for the best possible outcome.

29 Aug 2012

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Pulmatrix, Inc., a clinical stage biotechnology company creating novel inhaled therapeutics, announced today that three posters on its lead iCALM therapeutic, the first treatment developed utilizing its iSPERSE inhaled drug platform, will be presented at the European Respiratory Society (ERS) Annual Congress taking place September 1-5, 2012, in Vienna, Austria.

28 Aug 2012

South Sudan refugee health situation 'alarming,' U.N. warns

"The situation of 170,000 Sudanese refugees living in camps and settlements across South Sudan's Unity and Upper Nile states is alarming and there are worries about an outbreak of cholera, U.N. refugee agency officials said on Friday," the Associated Press/Washington Post reports.

28 Aug 2012

Allegro Diagnostics announces results from BronchoGen genomic test trial on lung cancer

Allegro Diagnostics today announced that results from its AEGIS (Airway Epithelium Gene Expression In the Diagnosis of Lung Cancer) clinical trials, to determine the accuracy of the BronchoGen genomic test, have been accepted for an oral presentation during the late-breaking abstract session at CHEST 2012 on Tuesday, October 23, 2012 at 4:30 p.m. The abstract will also be published in a supplement of the October 2012 issue of CHEST.

28 Aug 2012

Study explains how breast milk fosters colonies of microbiotic flora in a newborn's intestinal tract

The benefits of breast milk have long been appreciated, but now scientists at Duke University Medical Center have described a unique property that makes mother's milk better than infant formula in protecting infants from infections and illnesses.

28 Aug 2012

Respiratory News and Research

Researchers define new treatment for potentially fatal lung disease in patients with CVID

French data highlight women under 60 at risk for heart disease

Tunes and T-shirts for cardiac rehabilitation

Less than half of U.S. schools address pandemic preparedness in their school plan

FDA approves Ironwood’s LINZESS to treat irritable bowel syndrome with constipation

Sosei’s QVA149 Phase III study on COPD meets primary endpoint

Physical, verbal reminders could improve preoperative preparation

Emergency readmission after endoscopy linked to mortality risk

Anastomotic leakage does not increase rectal cancer recurrence risk

Janssen receives FDA Priority Review for ZYTIGA sNDA to treat mCRPC

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

Vitamin to the rescue in fight with ‘superbugs’

Physicians’ emotional, institutional barriers prolong medical futility at end of life

AstraZeneca’s ticagrelor receives Class I recommendation from ESC

New Wilderness Medical Society guidelines for prevention and treatment of lightning injuries

NUI Galway project hopes to deliver cost effective tool for rapid diagnosis of pneumonia

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

South Sudan refugee health situation 'alarming,' U.N. warns

Allegro Diagnostics announces results from BronchoGen genomic test trial on lung cancer

Study explains how breast milk fosters colonies of microbiotic flora in a newborn's intestinal tract

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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