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Mallinckrodt receives FDA approval for 32 mg tablet strength of EXALGO

The U.S. Food and Drug Administration (FDA) has notified Mallinckrodt, the pharmaceuticals business of Covidien, that it has approved a 32 mg tablet strength of EXALGO (hydromorphone HCI) Extended-Release Tablets (CII) for opioid-tolerant patients with moderate-to-severe chronic pain requiring continuous around-the-clock opioid analgesia for an extended period of time.

27 Aug 2012

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

New data to be presented at the Annual Congress of the European Respiratory Society (ERS 2012), in Vienna, Austria, will shed light on the current and potential future role of tiotropium, the first once-daily long-acting inhaled anticholinergic for patients with Chronic Obstructive Pulmonary Disease (COPD).

27 Aug 2012

Profilin-1 gene influences survival time in Lou Gehrig's disease

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

27 Aug 2012

PEI adjuvant improves effect of vaccines against flu, HIV and herpes

Oxford University scientists have discovered a compound that greatly boosts the effect of vaccines against viruses like flu, HIV and herpes in mice.

26 Aug 2012

Revision surgery improves upper limb amputation outcome

Revision surgery can significantly reduce pain and increases prosthesis use in veterans who undergo combat-related major upper-extremity amputation, US research demonstrates.

24 Aug 2012

Radiating fears over diabetes in childhood cancer survivors

People who undergo pancreatic irradiation during childhood cancer therapy are at an increased risk for developing diabetes later in life, report researchers.

24 Aug 2012

Sleep apnea is not necessarily a male disorder

Women, particularly those with hypertension or obesity, have high rates of sleep apnea, study findings show.

24 Aug 2012

Bleeding risk from aneurysm high in hemorrhagic AVM radiosurgery

In patients undergoing stereotactic radiosurgery for hemorrhagic arteriovenous malformations, endovascular or surgical strategies that reduce bleeding risk should be used if an aneurysm is found, advise US researchers.

24 Aug 2012

Guidelines for parents to beat back-to-school bugs

School bells are beginning to sound again across the country, so it will only be a matter of time until every parent comes face-to-face with a child who wakes up with a cold, fever or upset stomach.

24 Aug 2012

Influenza virus can change microRNA expression to control immune responses in human lung cells

When you are hit with the flu, you know it immediately -- fever, chills, sore throat, aching muscles, fatigue. This is your body mounting an immune response to the invading virus. But less is known about what is happening on the molecular level.

24 Aug 2012

Concern over ameba-infested tap water deaths

People with sinusitis who regularly treat their condition using nasal irrigation should be aware of a potential contamination risk associated with using inadequately filtered tap water, say US researchers.

23 Aug 2012

Adult surgery rescues overcorrected club foot deformity

Study findings support the use of supramalleolar osteotomy for patients with hindfoot valgus or subtalar joint deformity following an overcorrected clubfoot.

23 Aug 2012

Annual follow up after ESD for early gastric cancer recommended

Almost all recurrent lesions in gastric epithelial cancer could be cured by endoscopic submucosal resection with annual follow-up exams, say the authors of a Japanese study.

23 Aug 2012

Nonoperative management of inflamed gallbladder may be best for elderly

Medical rather than surgical management of acute cholecystitis – or inflamed gallbladder – may be the most appropriate option for elderly patients who may be unsuitable for surgery, report researchers.

23 Aug 2012

Lung cells not affected by tiny fibres: Study

Health risks posed to people who work with tiny fibres used in manufacturing industries could be reduced, thanks to new research.

23 Aug 2012

New results describe development of DC cancer vaccine with enhanced immunogenic potential

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Radboud University Nijmegen Medical Centre in the Netherlands announced today that they have published new pre-clinical results in the journal Cancer Immunology Immunotherapy describing the development of a dendritic cell (DC) cancer vaccine with enhanced immunogenic potential.

23 Aug 2012