Blindness News and Research

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Insight into mechanical properties that break the outer segment of photoreceptors

Light-sensing cells in the eye rely on their outer segment to convert light into neural signals that allow us to see. But because of its unique cylindrical shape, the outer segment is prone to breakage, which can cause blindness in humans. A study published by Cell Press on January 22nd in the Biophysical Journal provides new insight into the mechanical properties that cause the outer segment to snap under pressure.

23 Jan 2013

Hearing loss is associated with accelerated cognitive decline and impairment in older adults

Hearing loss appears to be associated with accelerated cognitive decline and cognitive impairment in a study of older adults, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

22 Jan 2013

Gene therapy improves vision but does not halt progression of cell loss

Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused by mutations in a gene (RPE65) required for recycling vitamin A in the retina.

22 Jan 2013

Regular aspirin use appears to be associated with increased risk of neovascular AMD

Regular aspirin use appears to be associated with an increased risk of neovascular age-related macular degeneration (AMD), which is a leading cause of blindness in older people, and it appears to be independent of a history of cardiovascular disease and smoking, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

22 Jan 2013

New report highlights links between NTDs and socio-economic prosperity

A recently released report, entitled "Social and Economic Impact Review on Neglected Tropical Diseases," highlights links between neglected tropical diseases (NTDs) and socio-economic prosperity.

19 Jan 2013

SF3B1 gene mutations in uveal melanoma linked to favorable features

Melanomas that develop in the eye often are fatal. Now, scientists at Washington University School of Medicine in St. Louis report they have identified a mutated gene in melanoma tumors of the eye that appears to predict a good outcome.

17 Jan 2013

Eyes also need light to develop normally during pregnancy

New research in Nature concludes the eye – which depends on light to see – also needs light to develop normally during pregnancy.

17 Jan 2013

WHO reports unprecedented progress against 17 neglected tropical diseases

WHO reports unprecedented progress against 17 neglected tropical diseases, thanks to a new global strategy, a regular supply of quality assured, cost-effective medicines and support from global partners.

17 Jan 2013

UCSF teams to study new ways to reduce childhood mortality and disease in developing nations

Two UCSF teams have received a total of $16 million from the Bill & Melinda Gates Foundation to study new ways to significantly reduce childhood mortality and disease in developing nations.

11 Jan 2013

New information on insulin and cell bonding mechanics

The discovery of insulin nearly a century ago changed diabetes from a death sentence to a chronic disease. Today a team that includes researchers from Case Western Reserve University School of Medicine announced a discovery that could lead to dramatic improvements in the lives of people managing diabetes.

11 Jan 2013

RPB honors Mass. Eye and Ear ophthalmologist with Senior Scientific Investigator Award

Reza Dana, M.D., M.P.H., M.Sc. of Mass. Eye and Ear/Harvard Medical School, was awarded the Research to Prevent Blindness (RPB) Senior Scientific Investigator Award in the amount of $150,000 to support research into the causes, treatment and prevention of blinding diseases.

9 Jan 2013

New study finds that adults with diabetes in Ontario get fewer government-funded eye exams

A new study has found that adults with diabetes in Ontario are getting significantly fewer government-funded eye exams than they were a decade ago, a key component of high-quality diabetes care essential to preventing diabetes-related eye complications.

8 Jan 2013

Study highlights role of Protein S in maintenance of healthy retina

Researchers at the Hebrew University of Jerusalem, in collaboration with researchers at the Salk Institute in California, have found for the first time that a specific protein is essential not only for maintaining a healthy retina in the eye, but also may have implications for understanding and possibly treating other conditions in the immune, reproductive, vascular and nervous systems, as well as in various cancers.

7 Jan 2013

UCSB scientists publish groundbreaking study results of Type 2 diabetes

While legions of medical researchers have been looking to understand the genetic basis of disease and how mutations may affect human health, a group of biomedical researchers at UC Santa Barbara is studying the metabolism of cells and their surrounding tissue, to ferret out ways in which certain diseases begin.

7 Jan 2013

Researchers identify four new genetic regions associated with Behcet's disease

Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road.

7 Jan 2013

Scientists develop two novel model systems for human corneal endothelium

Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. Cell loss due to aging or corneal endothelial disorders, such as Fuchs dystrophy, can lead to cornea edema and blindness, resulting in the need for cornea transplants.

28 Dec 2012

Two recent experimental treatments improve visual function in mouse models of retinitis pigmentosa

Two recent experimental treatments - one involving skin-derived induced pluripotent stem (iPS) cell grafts, the other gene therapy - have been shown to produce long-term improvement in visual function in mouse models of retinitis pigmentosa (RP), according to the Columbia University Medical Center (CUMC) scientists who led the studies. At present, there is no cure for RP, the most common form of inherited blindness.

20 Dec 2012

Aspirin use may increase risk of age-related macular degeneration

People who regularly took aspirin 10 years prior to examination had a small but statistically significant increase in the risk of a subtype of age-related macular degeneration (AMD), according to a study by University of Wisconsin-Madison researchers.

20 Dec 2012

Guardian examines challenges of eliminating river blindness in Africa

The Guardian's "Global Development Professionals Network" blog "reports on the challenges of eliminating river blindness from Africa by 2025."

18 Dec 2012

Consuming whole eggs may improve blood lipids, new research suggests

It is estimated that 34% of Americans are affected by an increasingly prevalent condition known as metabolic syndrome which is a combination of at least three of the following risk factors: large waistline, high triglycerides, low HDL cholesterol, high blood pressure and elevated blood sugar.

15 Dec 2012

Blindness News and Research

Insight into mechanical properties that break the outer segment of photoreceptors

Hearing loss is associated with accelerated cognitive decline and impairment in older adults

Gene therapy improves vision but does not halt progression of cell loss

Regular aspirin use appears to be associated with increased risk of neovascular AMD

New report highlights links between NTDs and socio-economic prosperity

SF3B1 gene mutations in uveal melanoma linked to favorable features

Eyes also need light to develop normally during pregnancy

WHO reports unprecedented progress against 17 neglected tropical diseases

UCSF teams to study new ways to reduce childhood mortality and disease in developing nations

New information on insulin and cell bonding mechanics

RPB honors Mass. Eye and Ear ophthalmologist with Senior Scientific Investigator Award

New study finds that adults with diabetes in Ontario get fewer government-funded eye exams

Study highlights role of Protein S in maintenance of healthy retina

UCSB scientists publish groundbreaking study results of Type 2 diabetes

Researchers identify four new genetic regions associated with Behcet's disease

Scientists develop two novel model systems for human corneal endothelium

Two recent experimental treatments improve visual function in mouse models of retinitis pigmentosa

Aspirin use may increase risk of age-related macular degeneration

Guardian examines challenges of eliminating river blindness in Africa

Consuming whole eggs may improve blood lipids, new research suggests

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