Omicron News and Research

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Hospitalization for COVID-19 may increase the risk of later readmission or death

People who had been hospitalized for COVID-19 in 2020 - and survived for at least one week after discharge - were more than twice as likely to die or be readmitted to the hospital in the next several months compared to the general population, according to new research in PLOS Medicine.

26 Jan 2022

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

In a new study, researchers evaluated SARS-CoV-2 vaccination-induced T cell responses cross-recognition among the early and novel SARS-CoV-2 variants.

26 Jan 2022

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

An interdisciplinary team of researchers from Europe analyzed the alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients.

26 Jan 2022

The new Omicron subvariant BA.2: what we know so far

Presently, an Omicron subvariant known as BA.2, first identified in late 2021, has made headlines due to its rapid spread.

26 Jan 2022

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

In a new study, scientists have compared the Omicron variant with the Delta VOC (B.1.617.2) as well as the wildtype strain (B.1), with respect to their interaction with the antiviral type 1 interferon response in infected cells.

26 Jan 2022

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

A recent study analyzed the effects of the interaction between SARS-CoV-2 Omicron spike amino acid and the human ACE2 receptor or with human antibodies.

26 Jan 2022

DoD Awards Contract to Siemens Healthineers to Purchase COVID-19 Antigen Over-the-Counter Test Kits in Support of POTUS' 500 Million Free At-Home COVID-19 Tests

On Jan. 21, 2022, the Department of Defense (DoD) awarded a contract to Siemens Healthineers to procure 50 million over-the-counter COVID-19 test kits.

From Siemens Healthineers 26 Jan 2022

SARS-CoV-2 infection and vaccination-induced T cells cross-recognize Omicron

In a recent study posted to the Nature In Review* preprint server, researchers performed a comprehensive, in-depth comparison of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell epitope repertoire following natural infection of coronavirus disease 2019 (COVID-19) compared to messenger ribonucleic acid (mRNA) vaccinations.

25 Jan 2022

Heterologous vaccine schedule provides extraordinary response to third dose of coronavirus vaccines

A third, booster dose of either the ChAdOx1 nCoV-19 (Oxford-AstraZeneca), BNT162b2 (Pfizer-BioNTech), AD26.COV2-S (Janssen) or CoronaVac (SinoVac) coronavirus vaccine induce a significant increase in antibody levels in those who have previously received two doses of CoronaVac.

25 Jan 2022

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

A new study assesses the effectiveness of two and three doses of the BNT162b2 vaccine against Omicron-related hospitalizations.

25 Jan 2022

Scientists find reduced vaccine efficacy against Omicron in South Africa and 50 other countries

In a new study, researchers evaluated the impact of the SARS-CoV-2 Omicron variant on the prevalence of SARS-CoV-2 infections among unvaccinated and vaccinated populations of South Africa and 50 other countries.

25 Jan 2022

Growth advantage of SARS-CoV-2 Omicron variant found to be partly due to shorter serial interval

In a new study, a team of researchers assessed how serial intervals of SARS-CoV-2 Omicron and Delta variants varied during the same time period in the Netherlands.

25 Jan 2022

Humoral correlate of protection for SARS-CoV-2 may reduce COVID-19 infection risk

In a new study, a team of researchers reviewed the published literature to find evidence for humoral SARS-CoV-2 correlate of protection (CoP).

25 Jan 2022

Accelerating the COVID-19 booster vaccination rate to prevent Omicron variant hospitalizations and deaths

A new study investigates the impact of accelerating the pace of COVID-19 booster vaccination rates in the US in reducing COVID-19-related hospitalizations and mortalities.

25 Jan 2022

Broad and potent neutralizing activity of human IgG1 LALA antibody against SARS-CoV-2 variants

A new study has focused on the identification, in vitro binding, and potent neutralizing activity of STI-9167 (plutavimab) against live viruses and pseudotype viruses.

25 Jan 2022

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

In a new study, researchers assessed the extent and duration of the neutralization of SARS-CoV-2 Omicron variant of concern after the administration of two and three doses of the BNT162b2 mRNA vaccine.

25 Jan 2022

Immunogenicity to BNT162b2 booster in adults who had previously received inactivated COVID-19 vaccination

A new preprint available on medRxiv* demonstrates the marked improvement in the immune response when the mRNA vaccine BNT162b2, from Pfizer/BioNTech, is used for the third dose after a primary two-dose series of an inactivated whole virus vaccine.

25 Jan 2022

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors.

25 Jan 2022

Protection against SARS-CoV-2 Omicron afforded by Pfizer-BioNTech and Moderna boosters compared to two-dose primary series

The current paper compares the effectiveness of two vs. three doses of these vaccines against Omicron compared to Delta.

25 Jan 2022

Scientists develop a model to rapidly identify vaccine breakthrough SARS-CoV-2 variants

In a new study, scientists have recently developed a computational model to predict the antigenicity and immune escape ability of emerging variants of SARS-CoV-2.

25 Jan 2022

Omicron News and Research

Hospitalization for COVID-19 may increase the risk of later readmission or death

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

The new Omicron subvariant BA.2: what we know so far

SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

Effects of the Omicron spike amino acid changes in the interaction with human ACE2 receptor or human antibodies

DoD Awards Contract to Siemens Healthineers to Purchase COVID-19 Antigen Over-the-Counter Test Kits in Support of POTUS' 500 Million Free At-Home COVID-19 Tests

SARS-CoV-2 infection and vaccination-induced T cells cross-recognize Omicron

Heterologous vaccine schedule provides extraordinary response to third dose of coronavirus vaccines

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

Scientists find reduced vaccine efficacy against Omicron in South Africa and 50 other countries

Growth advantage of SARS-CoV-2 Omicron variant found to be partly due to shorter serial interval

Humoral correlate of protection for SARS-CoV-2 may reduce COVID-19 infection risk

Accelerating the COVID-19 booster vaccination rate to prevent Omicron variant hospitalizations and deaths

Broad and potent neutralizing activity of human IgG1 LALA antibody against SARS-CoV-2 variants

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

Immunogenicity to BNT162b2 booster in adults who had previously received inactivated COVID-19 vaccination

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

Protection against SARS-CoV-2 Omicron afforded by Pfizer-BioNTech and Moderna boosters compared to two-dose primary series

Scientists develop a model to rapidly identify vaccine breakthrough SARS-CoV-2 variants

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