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Suspect protein HMGB1 found to promote DNA repair, prevent cancer

An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science.

21 Jul 2008

21 new genes found for Crohn's disease

A consortium of researchers from the United States, Canada, and Europe has identified 21 new genes for Crohn's disease, a chronic disease of the large and small intestines.

21 Jul 2008

Could arthritis wonder drugs provide clues for all disease?

Drugs that have helped treat millions of rheumatoid arthritis sufferers may hold the key to many more medical conditions, including atherosclerosis - a leading cause of heart disease - says the researcher who jointly invented and developed them.

From The University of Manchester 17 Jul 2008

An inflamed response

Paul Martin, Professor of Cell Biology in the University of Bristol Departments of Physiology and Pharmacology, and Biochemistry, talked to Cherry Lewis about the discovery made in his lab that speeds up wound healing and reduces the size of the wound scar. She was interested not only in the discovery itself, but also in the processes and years of research that led up to it.

15 Jul 2008

Huntington's disease brain damage linked to overactive immune response in the bloodstream

The damage to brain tissue seen in Huntington's disease may be caused by an overactive immune response in the bloodstream and the brain, according to new findings from two teams of researchers at the University of Washington in Seattle and University College London. The findings will be published online July 14 in the Journal of Experimental Medicine.

14 Jul 2008

Insulin suppresses receptors that cause cascade of inflammation

Researchers at the University at Buffalo -- the first to identify the anti-inflammatory and cardioprotective properties of insulin -- now have discovered one pathway through which the hormone produces this effect.

13 Jul 2008

Liver protein fetuin-A linked to type 2 diabetes in seniors

The presence of a protein expressed by the liver which inhibits insulin action may identify individuals more likely to develop type 2 diabetes, according to a new study led by a researcher from the UCSD School of Medicine, to be published July 9 in the Journal of the American Medical Association.

9 Jul 2008

Fish oil supplements taken in last trimester could reduce risk of child developing asthma

Mothers who take fish oil supplements during the last trimester of their pregnancy could be reducing the risk of their child going on to develop asthma, claims a study published today (9th July) in the American Journal of Clinical Nutrition (Am J Clin Nutr 2008;88:167-175).

9 Jul 2008

Farm-raised tilapia fish contains potentially dangerous fatty acid combination

"Farm-raised tilapia, one of the most highly consumed fish in America, has very low levels of beneficial omega-3 fatty acids and, perhaps worse, very high levels of omega-6 fatty acids, according to new research from Wake Forest University School of Medicine.

8 Jul 2008

Post-traumatic stress disorder causes early death from heart disease

Vietnam veterans who experienced posttraumatic stress disorder (PTSD) were twice as likely to die from heart disease as veterans without PTSD, a new Geisinger study finds.

8 Jul 2008

Resveratrol improves health, but not longevity in aging mice

Scientists have found that the compound resveratrol slows age-related deterioration and functional decline of mice on a standard diet, but does not increase longevity when started at middle age.

3 Jul 2008

Statins have unexpected effect on pool of powerful brain cells

Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.

3 Jul 2008

New insight into role of statins in dementia

3 Jul 2008

Genetic link between Crohn's and asthma discovered

Research into the genetic causes of Crohn's disease has revealed that the gene ORMDL3, known to be a risk factor for childhood asthma, is also associated with Crohn's disease, and in the process links between the condition and other diseases have been found.

2 Jul 2008

GILZ protein may have big role in making more bone and less fat

A small protein may have a big role in helping you make more bone and less fat, researchers say. "The pathways are parallel, and the idea is if you can somehow disrupt the fat production pathway, you will get more bone," says Dr. Xingming Shi, bone biologist at the Medical College of Georgia Institute of Molecular Medicine and Genetics.

1 Jul 2008

Asthma risk increases in children treated for HIV

Children whose immune systems rebound after treatment with potent anti-viral drugs for HIV infection face an increased risk of developing asthma, said a federally funded consortium of researchers led by those from Baylor College of Medicine in a report that appears online in the Journal of Allergy and Clinical Immunology.

1 Jul 2008

Being born over 10 pounds increases risk of developing rheumatoid arthritis

People who have a birthweight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birthweight, according to a study published by researchers from Hospital for Special Surgery online in advance of print in the Annals of the Rheumatic Diseases. While the mechanism for this association is unclear, the study identifies a potentially modifiable risk factor and highlights a potential way to decrease the incidence of the disease.

30 Jun 2008