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Pivotal study of dasotraline in adults with binge eating disorder meets primary endpoint

Sunovion Pharmaceuticals Inc. today announced that a study evaluating the efficacy and safety of dasotraline in adults with moderate to severe binge eating disorder met its primary endpoint, demonstrating a statistically significant decrease in number of binge days per week from baseline to Week 12 in the group treated with dasotraline 6 mg/day versus the placebo-treated group.

25 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Pediatric sepsis care within an hour increases chances of survival, shows study

More than one in 10 children hospitalized with sepsis die, but when a series of clinical treatments and tests is completed within an hour of its detection, the chances of survival increase considerably, according to a new analysis led by the University of Pittsburgh School of Medicine.

25 Jul 2018

New target for pneumonia seems to restore tight barriers and fluid clearance in the lungs

Severe pneumonia causes a buildup of fluid in the lungs that makes the basics of breathing and getting oxygen out to the body difficult to impossible.

25 Jul 2018

Omega-3 fatty acid supplements reduce disruptive behavior in children, shows study

Something as simple as a dietary supplement could reduce disruptive, even abusive behavior, according to newly released research by a team led by a UMass Lowell criminal justice professor.

25 Jul 2018

Single course of antibiotics early in childhood may increase risk for Type 1 diabetes

A single course of antibiotics early in childhood may increase risk for Type 1 diabetes. This is the finding of a study in mice led by researchers from NYU Medical School and published online July 24 in the journal eLife.

25 Jul 2018

Researchers find link between resilience to dyslexia and gray matter in the brain

Dyslexia, a reading disorder, is characterized by a difficulty in "decoding" -- navigating between the visual form and sounds of a written language.

24 Jul 2018

LGBQ teens at higher risk of diabetes than heterosexual youth, finds study

Lesbian, gay, bisexual and questioning youth are more likely to develop Type 2 diabetes, be obese and engage in less physical activity and more sedentary activities than heterosexual youth, a new Northwestern Medicine study has found.

24 Jul 2018

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows.

24 Jul 2018

Mutated gene linked to 3-year-old girl's severe neurological symptoms

A young girl with severe neurological symptoms finally has a diagnosis, following the discovery by the Translational Genomics Research Institute of a genetic mutation that likely caused the girl to experience a cascade of symptoms.

24 Jul 2018

Bioengineers build 3D model of human heart ventricle

Harvard University researchers have bioengineered a three-dimensional model of a human left heart ventricle that could be used to study diseases, test drugs and develop patient-specific treatments for heart conditions such as arrhythmia.

24 Jul 2018

So called "safe" food additives may not be so says AAP policy statement

The American Academy of Pediatrics (AAP) has released a new policy statement in the journal Pediatrics. Their statement says that at present there is little information regarding the cognitive and physiological effects of food additives and more information needs to be obtained.

23 Jul 2018

Outrage over China vaccines scandal

One of the largest vaccine manufacturers in China, Changchun Changsheng Bio-technology Ltd. was found to have falsified reports in connection with production and inspection of around 113,000 rabies vaccines.

23 Jul 2018

Researchers shed light on risks presented by residual disease for younger breast cancer patients

A new study from the Stanford Cancer Institute finds that young women who are treated with chemotherapy for breast cancer but have residual tumor in either the breast or lymph nodes have higher chances of recurrence compared to those with no evidence of any residual invasive tumor (pathologic complete response).

23 Jul 2018

Simple saliva test could lead to better prediction and prevention of diabetes

Diabetes assessment currently relies on measurement of blood sugar levels -- but a simple saliva sample could replace this, says new research.

23 Jul 2018

Children of mothers with type 1 diabetes at greater risk of being overweight

Children of mothers with type 1 diabetes are at significantly higher risk of being overweight and of exhibiting insulin resistance. This was published by scientists from Helmholtz Zentrum München and the Technical University of Munich in the journal 'Diabetologia'.

23 Jul 2018

New project explores health effects of dangerous chemicals

The EDC-MIXRISK project is exploring the health effects of a group of man-made substances that have been shown to disrupt the body’s endocrine system, the collection of hormone-producing glands that regulate growth and development, metabolism, reproduction and even mood and sleep patterns.

23 Jul 2018

Children News and Research

Pivotal study of dasotraline in adults with binge eating disorder meets primary endpoint

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Pediatric sepsis care within an hour increases chances of survival, shows study

New target for pneumonia seems to restore tight barriers and fluid clearance in the lungs

Omega-3 fatty acid supplements reduce disruptive behavior in children, shows study

Single course of antibiotics early in childhood may increase risk for Type 1 diabetes

Researchers find link between resilience to dyslexia and gray matter in the brain

LGBQ teens at higher risk of diabetes than heterosexual youth, finds study

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

Mutated gene linked to 3-year-old girl's severe neurological symptoms

Bioengineers build 3D model of human heart ventricle

So called "safe" food additives may not be so says AAP policy statement

Outrage over China vaccines scandal

Researchers shed light on risks presented by residual disease for younger breast cancer patients

Simple saliva test could lead to better prediction and prevention of diabetes

Children of mothers with type 1 diabetes at greater risk of being overweight

New project explores health effects of dangerous chemicals

Researchers investigate recessive genetic disorder that leads to childhood blindness

Study reports data on dementia prevalence in sexual minority older adults

Scientists create wearable device that measures cortisol in sweat

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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