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Applying more stringent ozone standards would minimize premature mortality and morbidity

Establishing a more stringent ozone standard in the U.S. would significantly reduce ozone-related premature mortality and morbidity, according to a new study published online July 18 in the journal Environmental Health Perspectives.

18 Jul 2012

PPAHS releases safety checklist that targets Patient-Controlled Analgesia

The Physician-Patient Alliance for Health & Safety (PPAHS), an advocacy group devoted to improving patient health and safety, today announced the release of a concise checklist that reminds caregivers of the essential steps needed to be taken to initiate Patient-Controlled Analgesia (PCA) with a patient and to continue to assess that patient's use of PCA.

18 Jul 2012

Ticagrelor ‘now on equal footing’ with other antiplatelets

The platelet aggregation inhibitor ticagrelor is now considered of equal effectiveness to clopidogrel and prasugrel for patients who have experienced a heart attack or have unstable angina, a report states.

17 Jul 2012

Hypomagnesemia signals nonrecovery of renal function in AKI

Researchers have identified hypomagnesemia as a risk factor for nonrecovery of renal function among critically ill patients with acute kidney injury.

17 Jul 2012

Arrhythmia finding could enhance COPD management

Arrhythmias could precede exacerbations in chronic obstructive pulmonary disease, raising the possibility of a new target for management and treatment, say researchers.

17 Jul 2012

Specific therapy may cut pneumonia mortality in HIV babies

The high mortality rate associated with acute severe pneumonia-related respiratory failure in infants exposed to or infected with HIV can be reduced to 30% if a treatment plan involving antibiotics, ventilation, and fluid restriction is used, researchers report.

17 Jul 2012

Light reflexes during CPR may indicate survival chances

The presence of the papillary light reflex during cardiopulmonary resuscitation is associated with early survival and favorable neurologic status during recovery, suggest findings from a case series.

17 Jul 2012

Sorting rhinosinusitis symptoms by ‘SNOT-22’

The three leading symptoms for chronic rhinosinusitis are nasal blockage, alterations to smell/taste, and needing to blow the nose, report UK researchers.

17 Jul 2012

AstraZeneca plans to conduct ticagrelor plus clopidogrel clinical trial for PAD

AstraZeneca today announced plans to conduct the EUCLID study, a global clinical trial involving 11,500 patients with peripheral artery disease (PAD), a condition affecting approximately 27 million people in Europe and North America.

17 Jul 2012

Athletes return to elite sport after hip reconstruction

Around three-quarters of elite athletes who undergo arthroscopic labral reconstruction of the hip successfully return to their sport at the same level of competition they were at prior to surgery, a review shows.

16 Jul 2012

Treatment deteriorates giant cell arteritis imaging sensitivity

Patients with suspected giant cell arteritis should undergo imaging before or as soon as possible after treatment has started to minimize the chance of a false–negative result, advise German researchers.

16 Jul 2012

Prostate cancer treatment regrets linked to comorbidity

Men with cardiovascular disease are significantly more likely to regret their prostate cancer treatment choice than men without this comorbidity and have an increased risk for adverse effects, US researchers warn.

16 Jul 2012

Positive results from Alnylam’s ALN-TTR02 Phase I trial on TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive clinical results from its Phase I trial with ALN-TTR02, an RNAi therapeutic targeting the transthyretin (TTR) gene for the treatment of TTR-mediated amyloidosis.

16 Jul 2012

UMMS scientists identify new genetic mutation that causes familial ALS

A new genetic mutation that causes familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease, has been identified by a team of scientists led by researchers at the University of Massachusetts Medical School (UMMS).

16 Jul 2012

Researchers discover HVEM’s unknown role in fighting off E. coli infections

Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the world. But the research community is gaining ground. In a major finding, published today in the scientific journal Nature, researchers from the La Jolla Institute for Allergy & Immunology have discovered a molecule's previously unknown role in fighting off E. coli and other bacterial infections, a discovery that could lead to new ways to protect people from these dangerous microorganisms.

16 Jul 2012

Researchers link newly discovered gene mutations to ALS

Researchers have linked newly discovered gene mutations to some cases of the progressive fatal neurological disease amyotrophic lateral sclerosis - ALS, also known as Lou Gehrig's disease. Shedding light on how ALS destroys the cells and leads to paralysis, the researchers found that mutations in this gene affect the structure and growth of nerve cells.

16 Jul 2012

College-age children also need immunizations, says UMDNJ professor

Most parents take their young children regularly for immunization shots that protect against polio, diphtheria, measles, mumps and other diseases. But many do not consider that their college-age children also need immunizations.

14 Jul 2012

New paper documents discovery of novel lipids, including MC3

Alnylam Pharmaceuticals, a leading RNAi therapeutics company, and collaborators announced today the publication of a scientific paper documenting the discovery of novel lipids used in second generation lipid nanoparticles (LNPs) for systemic delivery of RNAi therapeutics.

14 Jul 2012

Vitamin D deficiency may impair lung function in asthmatic children treated with budesonide

Vitamin D deficiency is associated with poorer lung function in asthmatic children treated with inhaled corticosteroids, according to a new study from researchers in Boston.

14 Jul 2012

Caution advised with succinylcholine in critically ill

The risk for hyperkalemia after succinylcholine use for urgent tracheal intubation increases the longer patients remain in the intensive care unit, research shows.

13 Jul 2012