Genetic News and Research

RSS

Yale study identifies racial and ethnic disparities in Oncotype DX testing for women with breast cancer

In a simple definition, cancer is a disease of the cells, which is caused by gene mutations. For a proportion of patients, including women with hormone receptor positive (HR+) breast cancer, gene expression profiling has a substantial impact on treatment decision-making by determining which patients might—or might not—respond to particular treatment options.

17 Mar 2017

Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

UT Southwestern researchers develop computer model to predict most deadly lung cancers

After evaluating more than 900 differences in the shape and structure of cancer cells, UT Southwestern Medical Center researchers developed a computer model able to predict the most deadly lung cancers based on a fraction of those features.

16 Mar 2017

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

A Maryland woman traveled to the Dominican Republic early in her pregnancy, spending three weeks with family. She felt dizzy and tired and, at first, attributed the lethargy to jet lag.

16 Mar 2017

Penn studies provide new understanding of lung cancer progression and prevention

Treating the brain with a preventative course of radiation may help Small Cell Lung Cancer (SCLC) patients - whose tumors often spread to their brain -- live longer, according to a new study from researchers in the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania.

16 Mar 2017

First physiological test opens door to early diagnosis of autism

An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study.

16 Mar 2017

Study uncovers genetic link to aggressive form of prostate cancer

An international study published in the Journal of the National Cancer Institute has identified a genetic connection to the aggressive form of prostate cancer.

16 Mar 2017

Dietary anti-cancer compound from broccoli may work by influence on long non-coding RNAs

Researchers have discovered one of the reasons why broccoli may be good for your health.

16 Mar 2017

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting healthy tissues.

16 Mar 2017

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Researchers at Beth Israel Deaconess Medical Center have gained new insight into the genetic and neuronal circuit mechanisms that may contribute to impaired sociability in some forms of Autism Spectrum Disorder.

16 Mar 2017

Study shows how mutations allow HCV to elude immune responses and vaccines

Unlike its viral cousins hepatitis A and B, hepatitis C virus (HCV) has eluded the development of a vaccine and infected more than 170 million people worldwide.

16 Mar 2017

Researchers unravel protein dosage compensation mechanism in genes

Researchers at Okayama University report in PLOS Genetics which genes from the yeast genome exhibit dosage compensation — the ability to temper protein production when the corresponding encoding gene’s copy number increases.

16 Mar 2017

Research findings advance development of HIV vaccines that induce broadly neutralizing antibodies

A Duke Health-led research team has described both the pathway of HIV protective antibody development and a synthetic HIV outer envelope mimic that has the potential to induce the antibodies with vaccination.

16 Mar 2017

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

Not all melanomas are created equal. While most melanomas appear on the skin as the result of sun exposure, a small subset of melanomas arise spontaneously from mucosal tissues.

15 Mar 2017

UB research yields neural crest cells from adult skin cells without genetic modification

A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.

15 Mar 2017

CUMC researchers discover common genetic variant that impacts brain aging

Columbia University Medical Center researchers have discovered a common genetic variant that greatly impacts normal brain aging, starting at around age 65, and may modify the risk for neurodegenerative diseases.

15 Mar 2017

LCSB researchers identify how the body influences differentiation of progenitor cells

Stem cells are unspecialised cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will differentiate, for example, into a blood, liver or nerve cell.

15 Mar 2017

Study findings could lead to novel therapies for preventing vision loss from degenerative retinal diseases

Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study.

15 Mar 2017

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder.

14 Mar 2017

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

Genetic News and Research

Yale study identifies racial and ethnic disparities in Oncotype DX testing for women with breast cancer

Scientists identify genetic clues to chronic kidney disease

UT Southwestern researchers develop computer model to predict most deadly lung cancers

Young researchers explore impact of prolonged Zika viremia in pregnant women, fetuses and infants

Penn studies provide new understanding of lung cancer progression and prevention

First physiological test opens door to early diagnosis of autism

Study uncovers genetic link to aggressive form of prostate cancer

Dietary anti-cancer compound from broccoli may work by influence on long non-coding RNAs

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Study provides insights into genetic, neuronal circuit mechanisms linked to autism's impaired sociability

Study shows how mutations allow HCV to elude immune responses and vaccines

Researchers unravel protein dosage compensation mechanism in genes

Research findings advance development of HIV vaccines that induce broadly neutralizing antibodies

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

UB research yields neural crest cells from adult skin cells without genetic modification

CUMC researchers discover common genetic variant that impacts brain aging

LCSB researchers identify how the body influences differentiation of progenitor cells

Study findings could lead to novel therapies for preventing vision loss from degenerative retinal diseases

Scientists create first model of anorexia nervosa using iPSCs derived from adolescent females

York researchers move closer to finding new treatments for chronic bladder diseases

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News