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PET images of microglial activation levels could better predict Alzheimer's disease progression

Researchers have discovered a way to better predict progression of Alzheimer's disease. By imaging microglial activation levels with positron emission tomography, researchers were able to better predict progression of the disease than with beta-amyloid PET imaging, according to a study published in the April issue of the Journal of Nuclear Medicine.

4 Apr 2019

Research identifies first case of a person without vitamin D binding protein

Research identifying the first case of a person living without the protein needed to bind and transport vitamin D in the bloodstream has been published in the New England Journal of Medicine.

4 Apr 2019

Study offers new hope for patients with decompensated cirrhosis

Decompensated cirrhosis is a chronic disease linked to numerous complications in its final stage. Professor Jonel Trebicka from Goethe University was involved in carrying out a pilot study demonstrating that the long-term administration of albumin in high doses stabilizes the circulatory function of these patients and protects them from sepsis.

4 Apr 2019

New genetic information behind urogenital track anomalies uncovered

About one in every 100 babies is born with some kind of developmental anomaly in the urogenital tract. In most cases abnormalities are mild, but sometimes life-long and even life-threatening disease develops.

4 Apr 2019

Bronchiectasis patients often display high sensitivity to airborne allergens

An international research team led by Nanyang Technological University, Singapore (NTU Singapore) has found that patients with the lung disease bronchiectasis also often display sensitivity to airborne allergens, and has highlighted the particular role that fungi appear to play.

4 Apr 2019

New computational model of human kinase may provide insights for cancer drug development

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers.

4 Apr 2019

New immune-based therapy eliminates HPV in one-third of women with cervical precancerous lesions

A potential new immune-based therapy to treat precancers in the cervix completely eliminated both the lesion and the underlying HPV infection in a third of women enrolled in a clinical trial.

4 Apr 2019

Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Since 1993, when the gene that causes Huntington's disease was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration.

4 Apr 2019

New technology could change the way gene editing is approached in future

Gene editing has been a much sought after and controversial technology. Last month, part of the World Health Organization called for an international registry to track all research into editing the human genome.

4 Apr 2019

Scientists identify new cell population that can help in regenerative processes

When organs or tissues are damaged, new blood vessels must form as they play a vital role in bringing nutrients and eliminating waste. This is the only way for organs and tissues to resume their normal function.

4 Apr 2019

Novel strategy to ameliorate symptoms of mitochondrial disease

Diseases affecting mitochondria, the powerhouses of our cells, are often caused by mutations in the mitochondrial DNA. Symptoms of such mitochondrial diseases in mice can be ameliorated by increasing their levels of mitochondrial DNA, according to a study by researchers at Karolinska Institutet.

3 Apr 2019

UCR study: Surgery associated with higher survival of patients with HER2-positive stage 4 breast cancer

A student at the University of California, Riverside, presented research results at the annual meeting of the American Association for Cancer Research, or AACR, in Atlanta showing that surgery is associated with higher survival rates for patients with HER2-positive stage 4 breast cancer compared with those who did not undergo surgery.

3 Apr 2019

New study debunks link between depression risk and 18 genes

Over the past quarter-century, researchers have published hundreds of studies suggesting a small set of particular genes or gene-variants plays a substantial role in boosting susceptibility to depression.

3 Apr 2019

Salk researchers reveal new role for a driver of metastatic cancers

Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print version of Genes & Development on April 1, 2019.

3 Apr 2019

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

Syngene, a world-leading manufacturer of image analysis solutions, today announced its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at a major London university to speed up analysis of proteins, DNA and cells associated with breast and a range of other cancer types.

From Syngene 3 Apr 2019

Postnova Analytics offers customer-friendly high performance MALS detector

The PN3621 Multi-Angle Light Scattering detector from Postnova Analytics combines outstanding performance, high precision and reliability design features to facilitate advanced characterization of proteins, conjugates, macromolecules, and nanoparticles.

From Postnova Analytics 3 Apr 2019