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Researchers use molecular simulations to understand lung cancer drug resistance

Scientists from the Universities of Bristol and Parma, Italy, have used molecular simulations to understand resistance to osimertinib - an anticancer drug used to treat types of lung cancer.

12 Feb 2018

Professor Jean-Charles Soria granted award for pioneering role in cancer drug development

The TAT 2018 Honorary Award for cancer drug development has been granted to Professor Jean-Charles Soria, for his pioneering role in cancer drug development across molecular targeted agents, precision medicine, and immunotherapy.

12 Feb 2018

New biomarker may indicate success of popular treatment for atrial fibrillation

Johns Hopkins researchers report successful use of heart imaging to predict the benefit or futility of catheter ablation, an increasingly popular way to treat atrial fibrillation, a common heart rhythm disorder.

12 Feb 2018

New tool measures cell strength 100 times faster than current technologies

Engineers, doctors and scientists at UCLA and Rutgers University have developed a tool that measures the physical strength of individual cells 100 times faster than current technologies.

12 Feb 2018

New imaging system helps predict chemotherapy responses in breast cancer

A new optical imaging system which uses infrared light has shown promise in predicting early responses to chemotherapy in breast cancer patients.

12 Feb 2018

Could a rare, deadly ‘superbug’ fungus be gaining a foothold?

The number of U.S. patients infected with a rare but dangerous fungal "superbug" called Candida auris has climbed quickly to 200 as of Dec. 31, according to the latest figures from the federal Centers for Disease Control and Prevention.

12 Feb 2018

Expert lists 5 common indications that a co-worker could be suffering from addiction

Alcohol and drug-related deaths continue to be a problem in the UK, with the Office for National Statistics reporting that the number of people dying from alcohol and drug abuse has continued to increase over the last decade.

12 Feb 2018

Chemist finds how to control blood sugar without usual side effects

Chemist Robert Doyle in the College of Arts and Sciences at Syracuse University has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.

11 Feb 2018

UA scientist develops database to alert physicians about carbohydrate count in medications

A physician-scientist at the University of Arizona College of Medicine-Phoenix has developed a new database to ensure that individuals on ketogenic diets to help treat a certain kind of epilepsy are not prescribed potentially life-threatening medications that contain carbohydrates.

11 Feb 2018

Researchers create new device to accelerate, improve accuracy of drug screening process

McMaster University engineers have devised a way to make testing for new drugs more efficient and affordable, and reduce the time for helpful medications to reach the public.

9 Feb 2018

Gene expression is rhythmic in most tissue types

Researchers have mapped primate gene expression throughout the day and discovered that the majority of critical gene activity is time dependent, which may aid the development of new treatments for many diseases.

9 Feb 2018

New faster and cheaper method developed to drug test athletes

It will now be easier, faster and cheaper to catch athletes who take performance-enhancing drugs. A new way of testing blood and urine developed by University of Waterloo researchers cuts down the time required to analyze samples from 30 minutes to 55 seconds. They're working to reduce it even further to 10 seconds per sample by using a fully automated workflow.

8 Feb 2018

Scientists design new triple labeling technique to analyze stem cell division

A joint team of scientists from Russia and the United States designed a method for marking dividing stem cells with three different labels.

8 Feb 2018

Scientists develop new technique to 'turn off' multi-drug resistance capabilities in cancer cells

The ability for cancer cells to develop resistance to chemotherapy drugs - known as multi-drug resistance - remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists could one day direct cancer cells to "turn off" their resistance capabilities.

8 Feb 2018

Researchers fabricate artificial device mimicking blood-brain barrier

Researchers at IIT-Istituto Italiano di Tecnologia fabricated an artificial device reproducing a 1:1 scale model of the blood-brain barrier, the anatomical and functional structure that protects the central nervous system from external substances, such as contaminants, but also drugs when they are injected intravenously into the body.

8 Feb 2018

Biomedical engineers develop miniature self-sealing wound model

Biomedical engineers have developed a miniature self-sealing model system for studying bleeding and the clotting of wounds. The researchers envision the device as a drug discovery platform and potential diagnostic tool.

8 Feb 2018

Researchers describe human blood-nerve barrier transcriptome for the first time

Human peripheral nerves -- all the nerves outside of the central nervous system -- are protected by the blood-nerve barrier. This is a tight covering of endothelial cells that maintains the microenvironment within the nerves by restricting the amounts or types of water, ions, solutes and nutrients that can reach the axons, or electric cables within the nerves, from the blood circulation system.

8 Feb 2018

Research project succeeds in palliating kidney disease caused by diabetes in mice

Diabetes has become a major health problem worldwide; some estimates suggest that in twenty years' time there will be around 600 million diabetics. The disease is caused by impaired insulin secretion, which in turn hinders cell glucose uptake; as a result, sugar levels in the bloodstream remain excessively high.

8 Feb 2018

New blood test offers quick, accurate diagnosis of deadly yeast infection

A new blood test seems to perform as well as, if not better than, traditional blood cultures at detecting a type of fungal yeast infection that commonly strikes hospital patients, according to an analysis led by UPMC.

8 Feb 2018

Researchers test effectiveness of investigational drug in treating diastolic dysfunction of the heart

Researchers at the University of Colorado School of Medicine have identified a potential treatment target for patients with a common type of heart failure.

8 Feb 2018