Tumor News and Research

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MicroRNA switches off tumor protection

The microRNA miR-21 suppresses the production of tumor suppressor Pdcd4, which protects cells from cancer development.

29 Nov 2007

Scientists observe gene activity outside the body

Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer Center in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body.

29 Nov 2007

Positron emission tomography may improve lung cancer diagnosis

Tumor imaging with positron emission tomography (PET) may improve the diagnosis and subsequent treatment of lung cancer patients, according to a review published online November 27 in the Journal of the National Cancer Institute.

27 Nov 2007

MIT radar technology fights breast cancer

Treating breast cancer with a type of heat therapy derived from MIT radar research can significantly increase the effectiveness of chemotherapy, according to results from the fourth clinical trial of the technique reported online Nov. 25 in the journal Cancer Therapy.

27 Nov 2007

Discovery of key acute myeloid leukemia gene

A gene called N-Myc leads a double life in certain white blood cells, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.

27 Nov 2007

Cryoablation for bone cancer tumors reduces pain, study shows

Cryoablation, a procedure most commonly associated with destroying kidney and prostate tumors by freezing them, has been shown to offer durable pain relief of cancer that has spread to bone.

27 Nov 2007

Alcohol and tobacco use doesn't boost HPV-related cancer risk

Heavy smoking and drinking are known to cause head and neck cancer. Infection with human papillomavirus type 16 (HPV16), a common strain of the sexually-transmitted HPV virus, is another known risk factor for head and neck cancer, which affects about 500,000 people each year worldwide.

27 Nov 2007

Scientists create mouse resistant to cancer

A mouse resistant to cancer, even highly-aggressive types, has been created by researchers at the University of Kentucky.

27 Nov 2007

Blood-vessel blocker aids cancer-killing virus

Cancer-killing viruses are a promising therapy for incurable brain tumors, but their effectiveness has been limited in part because immune cells rapidly move in and eliminate them.

27 Nov 2007

Adding water-soluble polymer to anti-cancer drug helps reach brain tumors

Bioengineers at Yale and Cornell have created a modified chemotherapy that more effectively reaches and remains at the site of brain tumors — by adding a water-soluble polymer to the anti-cancer drug, according to a report in the November-December issue of Bioconjugate Chemistry.

27 Nov 2007

Non-Caucasians at higher risk for severe metastatic breast cancer pain

A new study finds significant racial differences in the risk of pain related to metastatic breast cancer.

26 Nov 2007

Discovery of new signaling molecule could lead to the development of new treatments for cancer

Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.

21 Nov 2007

Serum carcinoembryonic antigen level can reflect adrenal adenoma

The female patient, reported on the December 7 issue 45 of World J Gastroenterology, presented a rare case, with symptoms consistent with hyperadrenocorticism and hypercatecholaminism, and also had a Cushingoid appearance.

21 Nov 2007

How can we know early who will benefit from tumor target therapy?

The precise tailoring of tumor target treatment for patients with cancer is an unmet challenge.

21 Nov 2007

Whole-body positron emission tomography can reassure cervical cancer patients

Whole-body PET (positron emission tomography) scans done three months after completion of cervical cancer therapy can ensure that patients are disease-free or warn that further interventions are needed, according to a study at Washington University School of Medicine in St. Louis.

21 Nov 2007

FDA clears Veridex test for the monitoring of metastatic colorectal cancer

Veridex, LLC has announced that the U.S. Food and Drug Administration (FDA) has granted an expanded clearance for the CellSearch System to be used as an aid in the monitoring of metastatic colorectal cancer.

21 Nov 2007

The science of cancer health disparities in racial/ethnic minorities and the medically underserved

The latest biological, clinical and social research behind how cancer affects different racial and ethnic groups will be the focus of the first American Association for Cancer Research conference on the topic, entitled "The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved."

21 Nov 2007

Bortezomib pushes cancer cells into overdrive, so that they self-destruct

University of Michigan Comprehensive Cancer Center researchers have discovered that bortezomib, a promising cancer drug, is able to strike a blow against melanoma tumor cells by revving up the action of a cancer-promoting gene.

21 Nov 2007

Dyslexia expert Dr. Bruce McCandliss awarded Presidential honor

Dr. Bruce McCandliss, a psychologist at the Sackler Institute for Developmental Psychobiology and associate professor of psychology in psychiatry at Weill Cornell Medical College, has received a commendation by the President of the United States in the form of a Presidential Early Career Award for Scientists and Engineers (PECASE).

20 Nov 2007

Hormone norepinephrine may hasten the progression of certain blood cancers

Researchers here have shown that in cell cultures, the stress hormone norepinephrine appears to promote the biochemical signals that stimulate certain tumor cells to grow and spread.

20 Nov 2007