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Labeling update for Tibotec Therapeutics' PREZISTA tablets approved

Tibotec Therapeutics announced today that the U.S. Food and Drug Administration (FDA) has approved a labeling update for PREZISTA® (darunavir) tablets to include 96-week data from the ARTEMIS and TITAN studies.

29 Jan 2010

AIDS Healthcare Foundation bans Merck's sales representatives for unwarranted pricing of Isentress

AIDS Healthcare Foundation, the largest global AIDS organization which operates free AIDS treatment clinics in the US, Africa, Latin America/Caribbean, the Asia/Pacific Region and Eastern Europe, including 18 healthcare centers in California, Florida, and Washington, DC, has banned pharmaceutical sales representatives from Merck and Co. Pharmaceuticals, from calling on AHF’s medical providers and staff in its US healthcare centers.

27 Jan 2010

OHAfrica reaches significant milestone in HIV/AIDS treatment program in Africa

For more than five years, OHAfrica - through Tšepong Clinic - has helped support HIV/AIDS treatment and testing in Lesotho, a small country in southern Africa with the third highest HIV infection rate in the world.

22 Jan 2010

Controversy around Merck's pricing for its AIDS drug Isentress

The controversy around Merck and Co. Pharmaceuticals’ pricing for its key AIDS drug Isentress — at nearly $13,000 per patient yearly, the most expensive first line AIDS therapy on the US market today — continued this week following Merck’s reaction to recent public criticism of its AIDS drug pricing. Merck ramped up its damage control PR efforts, issuing a press release that sought to rewrite the history of Isentress and deflect attention by claiming AIDS Healthcare Foundation has been unfairly attacking them.

22 Jan 2010

New research suggests prolong breastfeeding is critical for reducing risk of gastroenteritis in infants

For African infants with HIV-positive mothers, reducing exposure to breast milk can lower the rate of HIV transmission. But new research suggests that longer periods of breastfeeding—at least 6 months—are critical for reducing the risk of potentially fatal gastroenteritis.

21 Jan 2010

Study: PrEP treatment offers protection against HIV transmission in humanized mice

Systemic pre-exposure administration of antiretroviral drugs provides protection against intravenous and rectal transmission of HIV in mice with human immune systems, according to a new study published January 21, 2010 in the online journal PLoS ONE.

21 Jan 2010

Acyclovir does not reduce risk of HIV transmission for people infected with both HIV and HSV-2

A five-year international multi-center clinical trial has found that acyclovir, a drug widely used as a safe and effective treatment taken twice daily to suppress herpes simplex virus-2 (HSV-2), which is the most common cause of genital herpes, does not reduce the risk of HIV transmission when taken by people infected with both HIV and HSV-2.

21 Jan 2010

National Institutes of Mental Health awards $8M for HIV research

A multidisciplinary research team at the Johns Hopkins University School of Medicine has been awarded $8 million in funding by the National Institutes of Mental Health to develop methods to rid the body of HIV.

20 Jan 2010

Preliminary data from Phase 1 study of Sangamo BioSciences' SB-728-T announced

Sangamo BioSciences, Inc. announced today that preliminary data from the University of Pennsylvania investigator sponsored Phase 1 safety study of Sangamo's zinc finger nuclease (ZFN) based product, SB-728-T, for HIV/AIDS were presented on Friday, January 15, 2010 at the Keystone Symposium Session "HIV Biology and Pathogenesis."

20 Jan 2010

CytoDyn commences enrollment in Cytolin clinical trial

Following approval of the Institutional Review Board, CytoDyn, Inc. has discharged its duty to register a clinical trial of Cytolin®, the Company’s lead product, with the government’s website at www.clinicaltrials.gov, ID NCT01048372. The public has online access to this federal database, which describes the key elements of clinical trials and their status.

19 Jan 2010

New issue from Annals of Internal Medicine

Prescriptions of some opioids, such as oxycodone, have increased significantly over the past decade. As long-term opioid therapy for chronic noncancer pain becomes more common, the deaths associated with opioids increase.

19 Jan 2010

Tragic consequences of AIDS denialism in South Africa

Despite irrefutable proof that HIV treatments have proven benefits, AIDS denialists continue to deny their value. In a paper just published online in Springer's journal AIDS and Behavior, Professor Myron Essex and Dr. Pride Chigwedere, from the Harvard School of Public Health AIDS Initiative in the US, provide additional proof that withholding HIV treatments with proven benefits led to the death of 330,000 people in South Africa as the result of AIDS denialist policies. They also show that the harm has not been reversed and highlight that when denialism enters public health practice, as in South Africa, the consequences are disastrous.

19 Jan 2010

Longer breastfeeding can prevent postnatal HIV transmission

A new study from Zambia suggests that halting breastfeeding early causes more harm than good for children not infected with HIV who are born to HIV-positive mothers.

18 Jan 2010

Study raises concerns about drug-resistant HIV

The emergence of drug-resistant strains of HIV could one day threaten efforts to control the global HIV pandemic, according to a study published online Thursday in the journal Science, HealthDay News/U.S. News & World Report reports. The researchers based their findings on "a mathematical model that tracks the transmission of multiple strains of HIV" in San Francisco, the news service writes (1/14).

18 Jan 2010

NIH, D.C. Department of Health partner to decrease the rate of new HIV infections

Officials from the National Institutes of Health and the city of Washington, D.C. today announced the new D.C. Partnership for HIV/AIDS Progress, a collaborative research initiative between NIH and the D.C. Department of Health designed to decrease the rate of new HIV infections in the city, improve the health of district residents living with HIV infection, and strengthen the city's response to the HIV/AIDS epidemic.

13 Jan 2010

UNAIDS chief calls for reduction in MTCT in Africa

UNAIDS Executive Director Michel Sidibe on Monday during a five-day trip in Kenya, called for a drastic reduction in mother-to-child transmission (MTCT) of HIV in sub-Saharan Africa, Capital News reports. "In our continent we still have 400,000 babies born every year with HIV and we know if we are capable of making sure that testing will become available universally to all our pregnant women, (and) that pregnant women also have access to treatment, we will prevent the transmission," Sidibe said (Karong'o, 1/11).

13 Jan 2010

AHF to host protest targeting Merck over the steep price for its key HIV/AIDS drug, Isentress

AIDS Healthcare Foundation (AHF) will host a protest Tuesday, January 12, at 10:30am targeting Merck and Co. Pharmaceuticals over the steep price for its key HIV/AIDS drug, Isentress, during the 28th Annual J.P. Morgan Healthcare Conference in San Francisco.

12 Jan 2010

Recent releases in Global Health

A Lancet Comment examines the "grossly insufficient" progress towards meeting the Millennium Development Goal (MDG) of reducing under-5 child mortality. "Accelerated progress can be achieved, even in the poorest environments, through: integrated, evidence-driven, and community-based programmes that focus on addressing the major causes of death, including pneumonia, diarrhoea, newborn disorders, malaria, HIV, and undernutrition; reaching the unreached with a basic package of interventions at large scale and achieving coverage with equity; and using data for action and advocacy," the comment concludes (You et al., 1/9).

9 Jan 2010

Young men with HIV infection have coronary atherosclerotic plaques: MGH study

A Massachusetts General Hospital (MGH) study has found that relatively young men with longstanding HIV infection and minimal cardiac risk factors had significantly more coronary atherosclerotic plaques - some involving serious arterial blockage - than did uninfected men with similar cardiovascular risk.

8 Jan 2010

Antiretroviral therapy improves health outcomes for HIV patients

High antiretroviral therapy adherence, which has been shown to be a major predictor of HIV disease progression and survival, is now associated with lower health care costs, according to researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Jan 2010