Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.

13 Apr 2018

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

The Center for Regenerative Medicine at Boston University and Boston Medical Center has engineered two new categories of lung epithelial cells in vitro using pluripotent stem cells.

12 Apr 2018

New population of lung stem cells may be key for regenerating airways after injury

The human airway is a system of branching tubes that connects the nose and mouth with the lungs and allows us to inhale air, extract the vital oxygen, and exhale the waste product carbon dioxide.

12 Apr 2018

ATS Foundation and Insmed to provide $50,000 funding for NTM lung disease research

The ATS Foundation is pleased to announce a new ATS Foundation/Insmed Research Award in Non-Tuberculous Mycobacteria Lung Disease, which will provide one year of funding support in the amount of $50,000.

12 Apr 2018

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.

10 Apr 2018

Cardiac fibroblasts contribute to heart disease

An article published in Experimental Biology and Medicine reports that supporting cells in the heart, known as fibroblasts, are selectively activated by factors present in heart disease.

9 Apr 2018

Insilico to present recent advances in AI for aging biomarkers and age management research

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, biomarker development and aging research, is pleased to announce the presentation of its Director of Drug Discovery, Dr. Ivan Ozerov, at the 24th Clinical Applications for Age Management Medicine Conference, April 27, 2018, organized by Age Management Medicine Group.

6 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

NYU Langone Health surgeons successfully perform first lung transplant procedure

Shortly after receiving final regulatory approval to launch a new lung transplant program, NYU Langone Health surgeons successfully performed the institution's first procedure, giving two new lungs - and a new lease on life - to a Brooklyn woman with a complicated form of pulmonary fibrosis.

2 Apr 2018

Study shows limitations of AAV gene therapy in treating hereditary adrenal disorders

A new study has definitively shown that a single treatment with gene therapy using adeno-associated viral (AAV) vector gene delivery to replace the defective gene responsible for congenital adrenal hyperplasia (CAH) will only temporarily alleviate the hereditary disorder.

29 Mar 2018

Research highlights methods to identify antibiotic related kidney damage in children with CF

New research, published in Nature Scientific Reports, conducted by the University and partners highlights effective methods for identifying a common side effect in children receiving drug treatments for Cystic fibrosis.

28 Mar 2018

UC researcher granted patent for potential pulmonary infection treatment

A researcher in the University of Cincinnati (UC) College of Medicine has been granted a U.S. patent for a potential treatment for a pulmonary infection in patients with cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD).

27 Mar 2018

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

27 Mar 2018

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Neem Biotech, a Wales-based R&D biotech working in the field of novel antimicrobial drug development, announced today that it will be presenting results of its ongoing development work into the impact of NX-AS-401, its lead candidate,on biofilms in chronic cystic fibrosis lung infections at the 15th European Cystic Fibrosis Basic Science Conference taking place from 21st to 24th March 2018 in LoutrakiKorinthias, Greece.

From Neem Biotech 22 Mar 2018

Researchers develop way to sequence entire fetal genome by modifying prenatal testing method

For the first time, researchers have developed a way to sequence the entire genome of a fetus by modifying the prenatal testing method known as amniocentesis.

16 Mar 2018

Researchers find way to identify undiagnosed genetic diseases in electronic health records

Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases.

16 Mar 2018

Gastrointestinal hormone offers possible new treatment for NAFLD and NASH patients

Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

9 Mar 2018

Dentists mysteriously succumbing to lung disease finds the CDC

The U.S. Centers for Disease Control and Prevention (CDC) has found nine dentists and dental healthcare workers with a progressive lung disease of which seven died. This was published in the CDC’s Morbidity and Mortality Weekly Report yesterday (8th March 2018).

8 Mar 2018

Innovative program seeks to eliminate HCV in Iceland

A new Journal of Internal Medicine study describes an innovative program to eliminate hepatitis C virus (HCV) as a public health threat in Iceland.

7 Mar 2018

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Pulmonary fibrosis, an ongoing process of scarring that leaves patients chronically short of breath, can progress in severity until the only course of treatment is lung transplant.

6 Mar 2018

Fibrosis News and Research

Further Reading

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

New population of lung stem cells may be key for regenerating airways after injury

ATS Foundation and Insmed to provide $50,000 funding for NTM lung disease research

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Cardiac fibroblasts contribute to heart disease

Insilico to present recent advances in AI for aging biomarkers and age management research

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

NYU Langone Health surgeons successfully perform first lung transplant procedure

Study shows limitations of AAV gene therapy in treating hereditary adrenal disorders

Research highlights methods to identify antibiotic related kidney damage in children with CF

UC researcher granted patent for potential pulmonary infection treatment

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Researchers develop way to sequence entire fetal genome by modifying prenatal testing method

Researchers find way to identify undiagnosed genetic diseases in electronic health records

Gastrointestinal hormone offers possible new treatment for NAFLD and NASH patients

Dentists mysteriously succumbing to lung disease finds the CDC

Innovative program seeks to eliminate HCV in Iceland

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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