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Two proteins may be survival markers in some breast cancers

New research suggests that the presence or absence of two proteins may be important markers for long-term survival in some breast-cancer patients.

13 Nov 2007

Zinc transporters regulate pancreatic cancer

Zinc, an important trace element for healthy growth and development, can be related to pancreatic cancer. Too much ZIP4, a molecule that enables the transport of zinc into cells, promotes the growth and spread of pancreatic tumors cells, said a group of researchers from Baylor College of Medicine in Houston, The University of Texas M.D. Anderson Cancer Center and the University of Florida in Gainesville, in a report which appears online today in the Proceedings of the National Academy of Sciences.

13 Nov 2007

Synthetic compound promotes death of lung-cancer cells, tumors

Human lung-cancer tumors grown in mice have been shown to regress or disappear when treated with a synthetic compound that mimics the action of a naturally occurring "death-promoting" protein found in cells, researchers at UT Southwestern Medical Center report.

13 Nov 2007

Research highlights important indicators of early-stage ovarian cancer

New research explains why some ovarian cancer patients are dying, while others survive, despite similar surgical and post-operative treatment.

13 Nov 2007

Discovery of key pathway, potential drug targets in autoinflammatory disease

Molecular biologists at Jefferson's Kimmel Cancer Center in Philadelphia have detailed the cascade of cellular events behind some potentially dangerous autoinflammatory diseases.

13 Nov 2007

FDA strengthens warnings for erythropoiesis-stimulating agents

The U.S. Food and Drug Administration has approved revised boxed warnings and other safety-related product labeling changes for erythropoiesis-stimulating agents (ESAs), which treat certain types of anemia.

13 Nov 2007

Cell response to stress signals predicts tumors in women with common pre-breast cancer

A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS.

13 Nov 2007

Molecular markers predict risk for invasive breast cancer years before the tumor develops

A team of scientists from the University of California San Francisco has identified distinct molecular markers that predict whether or not a woman is likely to develop subsequent invasive cancer after initial diagnosis with a noninvasive form of early breast cancer.

13 Nov 2007

New guidelines on non-muscle invasive bladder cancer

The AUA is pleased to announce their new Guideline on the Management of Nonmuscle Invasive Bladder Cancer. Each year, more than 60,000 people are diagnosed with bladder cancer, which has been linked to a number of risk factors, including cigarette smoking and exposure to hazardous chemicals.

13 Nov 2007

UK study looks at obesity in women

The study shows that overweight and obese women in the UK are at a higher risk of developing and dying from cancer.

6 Nov 2007

Synthetic version of chlorotoxin shows promise in treatment of brain tumors

A drug developed and tested at UAB (University of Alabama at Birmingham) targeted at malignant brain tumors known as glioma has shown promising results in a Phase 1 trial, according to results presented at the American Society for Therapeutic Radiology and Oncology annual meeting.

6 Nov 2007

Early diagnosis of prostate cancer

Treating prostate cancer is a race against time. By the time the patient can feel the first symptoms, the disease has usually spread too far.

6 Nov 2007

New finding about the relationship between stress and cancer

One way environmental stress causes cancer is by reducing the activity level of an enzyme that causes cell death, researchers say.

6 Nov 2007

Li-Fraumeni syndrome found, for the first time, in Singapore

A rare hereditary disorder that strongly predisposes carriers to develop cancer at an early age has been found in an Asian female, report researchers at the American Association for Cancer Research Centennial Conference on Translational Cancer Medicine.

6 Nov 2007

Modified Curcumin demonstrates even greater tumor suppressive properties

Curcumin, the yellowish component of turmeric that gives curry its flavor, has long been noted for its potential anti-cancer properties.

6 Nov 2007

Osteopontin-c is a good biomarker of breast cancer.

Researchers have identified a molecule that may be more accurate than existing biological signposts used to predict which breast cancers will develop into advanced forms of the disease.

6 Nov 2007

Antioxidants inositol and inositol hexaphosphate could provide all-purpose radiation protection

Two common dietary molecules found in legumes and bran could protect DNA from the harmful effects of radiation, researchers from the University of Maryland report.

6 Nov 2007

Cancer victim comes up with a possible alternative to chemo

A cancer victim has invented a machine that could well replace traditional chemotherapy for the treatment of the disease.

5 Nov 2007

New view of lung cancer genome

An international team of scientists, supported in part by the National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), have announced that its systematic effort to map the genomic changes underlying lung cancer has uncovered a critical gene alteration not previously linked to any form of cancer.

5 Nov 2007

How does the antitumor drug get to the cell nucleus?

Platinum complexes such as the well-known cisplatin are powerful antitumor medications. They cross the cell membrane and reach the nucleus, where they attach to DNA and stop cell growth. But how does cisplatin get to the nucleus Italian researchers have now proven that a copper transport protein may play a critical role.

5 Nov 2007