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Experts call for rigorous clinical trials in use of experimental fetal therapy

Citing uncertainties about the risks and benefits of an experimental therapy for fetuses whose kidneys do not develop, bioethicists at Johns Hopkins and a team of medical experts are calling for rigorous clinical trials in the use of a potential treatment, known as amnioinfusion.

12 Dec 2017

Researchers developing smartphone app to help patients with eating disorders

With a new $50,000 award from the National Eating Disorders Association, a research team at the University of Kansas is developing a smartphone app for clinical use with patients receiving treatment for an eating disorder -- the deadliest of all mental disorders.

12 Dec 2017

Chemical found in marijuana could help HIV patients maintain their mental function

A chemical found in marijuana, known as tetrahydrocannabinol, or THC, has been found to potentially slow the process in which mental decline can occur in up to 50 percent of HIV patients, says a new Michigan State University study.

12 Dec 2017

Scientists develop new method for more effective photothermal treatment of tumors

Nanorods made of bismuth sulfide kill tumor cells with heat when they are irradiated with near-infrared light. Chinese scientists are now making these weapons more powerful by remodeling the defect state of the nanorod crystal lattice by adding gold nanodots.

12 Dec 2017

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced new results from two studies with EndoPredict are being featured at the 2017 San Antonio Breast Cancer Symposium in San Antonio, Texas.

12 Dec 2017

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells.

12 Dec 2017

High-intensity exercise decreases worsening of motor symptoms in Parkinson's patients

High-intensity exercise three times a week is safe for individuals with early-stage Parkinson's disease and decreases worsening of motor symptoms, according to a new phase 2, multi-site trial led by University of Colorado Anschutz Medical Campus and Northwestern Medicine scientists.

12 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer.

11 Dec 2017

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Novel compound along with checkpoint inhibitors may enhance immune response in melanoma patients

A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

Modern non-invasive diagnostics can get clear picture of the heart’s condition

By no means are only elderly people at risk from heart diseases. Physically active individuals can also be affected, for example if a seemingly harmless flu bug spreads to the heart muscle. Should this remain undetected and if, for example, a builder continues with his strenuous job or an athlete carries on training, this can lead to chronic inflammation and in the worst case even to sudden death.

8 Dec 2017

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

Although combination antiretroviral therapy (cART) has improved survival of patients infected with HIV and has reduced the incidence of severe neurologic complications, almost half of cART-treated HIV patients experience some degree of neurocognitive impairment (neuroHIV).

8 Dec 2017

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

Researchers have discovered a mechanism of resistance to checkpoint inhibitors and how to reverse it. The biomarker results from the IMvigor210 study are reported at the ESMO Immuno Oncology Congress 2017.

8 Dec 2017

Therapy News and Research

Experts call for rigorous clinical trials in use of experimental fetal therapy

Researchers developing smartphone app to help patients with eating disorders

Chemical found in marijuana could help HIV patients maintain their mental function

Scientists develop new method for more effective photothermal treatment of tumors

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

High-intensity exercise decreases worsening of motor symptoms in Parkinson's patients

Study: Combination targeted therapy has high response rates in AML patients

Study provides new insights into mechanism of tumor survival in glioblastoma

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Combination of chemotherapy and targeted drug improves response in younger CLL patients

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Two immunotherapy approaches for multiple myeloma show hope

Novel compound along with checkpoint inhibitors may enhance immune response in melanoma patients

Modern non-invasive diagnostics can get clear picture of the heart’s condition

Study: Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients

Study finds mechanism of resistance to checkpoint inhibitors and way to reverse it

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