Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.

27 Jan 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017

Caspase-2 enzyme deficiency linked to higher cancer risk

Researchers from the Centre for Cancer Biology at the University of South Australia have found that a deficiency of caspase-2 enzymes place people at a higher risk of developing tumours.

25 Jan 2017

New stem cell method could lead to powerful treatments for skeletal system injuries

A recent study, affiliated with UNIST has developed a new method of repairing injured bone using stem cells from human bone marrow and a carbon material with photocatalytic properties, which could lead to powerful treatments for skeletal system injuries, such as fractures or periodontal disease.

23 Jan 2017

Study provides link between common mutations in blood cells of older adults and atherosclerosis

A new study provides some of the first links between relatively common mutations in the blood cells of elderly humans and atherosclerosis.

19 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Research offers new clues to prolong lifespan of the body's disease-fighting NK cells

A team of researchers from Australia and France have uncovered new insights into how to prolong the lifespan of the body's disease-fighting natural killer (NK) cells.

17 Jan 2017

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body.

17 Jan 2017

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer.

17 Jan 2017

Study reveals brain activity may be key to link between stress and heart disease

Increased activity in a deep-lying region of the brain called the amygdala is associated with a higher risk of heart attack and stroke, according to a study published in The Lancet. The amygdala is known to process emotions such as fear and anger and the finding sheds light on the possible mechanism by which stress can lead to cardiovascular disease (CVD), say the study authors.

12 Jan 2017

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease.

12 Jan 2017

New review finds successful outcomes for Achilles tendon tear with surgical and nonsurgical treatments

A new literature review published in the Journal of the American Academy of Orthopaedic Surgeons found successful outcomes for an Achilles tendon tear with either minimally invasive surgery or nonsurgical bracing with a removable boot, especially in recreational athletes.

10 Jan 2017

Researchers identify possible treatment targets for myelodysplasia syndromes

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells.

30 Dec 2016

Blocking protein that initiates immune response against viral infections may help combat HIV

In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help combat HIV.

23 Dec 2016

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

22 Dec 2016

Clinical study tests adult stem cell therapy for infants with congenital HLHS

In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine and the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).

21 Dec 2016

Bone Marrow News and Research

Further Reading

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

Researchers design antibody that recognizes and destroys blood cancer stem cells

Caspase-2 enzyme deficiency linked to higher cancer risk

New stem cell method could lead to powerful treatments for skeletal system injuries

Study provides link between common mutations in blood cells of older adults and atherosclerosis

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Research offers new clues to prolong lifespan of the body's disease-fighting NK cells

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Knowledge bank approach could help find best treatment option for AML patients

Study reveals brain activity may be key to link between stress and heart disease

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

New review finds successful outcomes for Achilles tendon tear with surgical and nonsurgical treatments

Researchers identify possible treatment targets for myelodysplasia syndromes

Blocking protein that initiates immune response against viral infections may help combat HIV

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Clinical study tests adult stem cell therapy for infants with congenital HLHS

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

FDA awards accelerated approval to new ovarian cancer drug

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

New clinical study for children with AML aims to kill leukemia cells and minimize cardiac damage

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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