Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

New study shows advantages of DNA barcoding technique for identifying nanoparticles

The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn't much help in predicting which nanoparticles will successfully enter the cells of living animals.

5 Mar 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

New research project to determine why mine dust-related lung diseases are on the rise

The passage of critical mine health and safety legislation in the late 1960s, along with advances in technology and safety practices, helped to decrease the prevalence of lung diseases for miners. But starting in the mid-1990s, there was a significant documented increase in lung diseases among coal workers, especially among younger workers.

24 Feb 2018

Replenishing a protein could improve healing properties of stem cell therapy after heart attack

Researchers may have found a way to reduce ongoing heart damage that occurs long after a severe heart attack by improving the longevity of stem cells injected into the heart.

13 Feb 2018

Researchers test effectiveness of investigational drug in treating diastolic dysfunction of the heart

Researchers at the University of Colorado School of Medicine have identified a potential treatment target for patients with a common type of heart failure.

8 Feb 2018

Researchers develop novel antibody-based therapy to treat organ fibrosis

Fibrosis can be triggered by many events- surgery, injury, disease- but regardless of the cause, it's characterized by accumulating masses of collagen-packed scar tissue that can permanently damage compromised organs.

6 Feb 2018

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Researchers have successfully identified the genetic cause of idiopathic pulmonary fibrosis and have shown success in trials of a new gene therapy.

1 Feb 2018

Discovery of molecular nets may lead to new treatment approach for heart failure

Local researchers have discovered that a group of molecules, called chondroitin sulfate, normally found only in connective tissues such as the cartilage, accumulates and causes inflammation in the hearts of patients with heart failure.

31 Jan 2018

Long-term intake of sunflower, fish oils affects the liver

An international group of scientists led by the University of Granada (UGR) has demonstrated that the long-term intake of sunflower or fish oils damages the liver and can cause a series of alterations in it, giving rise to non-alcoholic steatohepatitis.

31 Jan 2018

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment.

30 Jan 2018

Scientists use synthetic protein to disrupt bacteria’s ability to perform basic life functions

A synthetic protein that disrupts the ability of bacteria to perform basic life functions - moving, eating, attaching to hosts - could be a key to fighting infectious disease and preventing bacteria from evolving into drug-resistant pathogens.

27 Jan 2018

IPF Catalyst Challenge recognizes Owlstone Medical’s Breath Biopsy platform

Owlstone Medical Ltd, a diagnostics company developing a breathalyzer for disease, today announced it is one of the three winners of the global Idiopathic Pulmonary Fibrosis (IPF) Catalyst Challenge, sharing the $1,000.000 (£720,000 GBP) award, each receiving $333,333 (£240,000 GBP).

27 Jan 2018

Study offers way to predict onset of lung disease in children with cystic fibrosis

Cystic fibrosis (CF) shortens life by making the lungs prone to repeated bacterial infections and associated inflammation.

19 Jan 2018

LJI study reveals key player that promotes skin inflammation in atopic dermatitis

Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes skin inflammation in atopic dermatitis and the characteristic thickening of the skin.

18 Jan 2018

Computer model based on AI improves analysis of kidney biopsies

The ability to quantify the extent of kidney damage and predict the life remaining in the kidney, using an image obtained at the time when a patient visits the hospital for a kidney biopsy, now is possible using a computer model based on artificial intelligence.

11 Jan 2018

New HSS study may signal hope for patients suffering from scleroderma

Scleroderma is a terribly debilitating disease with no effective treatments and the mortality rates are still upwards of 20%-50%, the highest of any rheumatic disease.

11 Jan 2018

Malnutrition remains underdiagnosed, undertreated for decades among hospitalized patients

Malnutrition among hospitalized patients remains a serious issue that has been underdiagnosed and undertreated for decades.

9 Jan 2018

Researchers uncover powerful new model for studying hallmark of vascular disease

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin-Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.