Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

ACR announces revised classification criteria for rheumatoid arthritis

The American College of Rheumatology announced the release of revised classification criteria (created in collaboration with the European League Against Rheumatism) for rheumatoid arthritis, which will allow the study of treatments for RA at much earlier stages of the disease—before joint damage occurs—ultimately leading to better patient outcomes.

11 Aug 2010

CADTH Review Panel releases recommendations for Biologic Response Modifier Agents for Adults with RA

The Canadian Agency for Drugs and Technologies in Health's (CADTH) Therapeutic Review Panel released last week their recommendations for Biologic Response Modifier Agents for Adults with Rheumatoid Arthritis (RA).

10 Aug 2010

Ardea Biosciences second-quarter total revenues decline to $3.5 million

Ardea Biosciences, Inc., a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases, reported recent accomplishments and financial results for the second quarter and six months ended June 30, 2010.

7 Aug 2010

Incyte second-quarter total revenues increase to $49.8 million

Incyte Corporation today reported second quarter 2010 financial results and described progress for several of its clinical programs.

5 Aug 2010

Savient second-quarter net loss decreases to $5.0 million

Savient Pharmaceuticals, Inc. reported financial results for the three and six months ended June 30, 2010. The net loss for the second quarter of 2010 was $5.0 million, or $0.07 per basic and diluted share, on total revenues of $1.0 million, compared with a net loss of $54.8 million, or $0.92 per basic and diluted share on total revenues of $0.7 million for the second quarter of 2009.

4 Aug 2010

$International study of more than 60,000 women highlights additional risk associated with fractures$

International study of more than 60,000 women highlights additional risk associated with fractures

Researchers seeking to understand the impact of osteoporosis and fractures on various aspects of health have found that women who had previous fractures experienced a significant reduction in health-related quality of life similar to or worse than that experienced by patients with diabetes, arthritis, lung disease and other chronic illnesses. This latest study from the Global Longitudinal Study of Osteoporosis in Women (GLOW), which is based at the Center for Outcomes Research at the University of Massachusetts Medical School, was published online.

3 Aug 2010

Osteologix grants Servier Research Group exclusive license to develop, commercialize NB S101

Osteologix, Inc. through its wholly owned Irish subsidiary Osteologix Limited and the Servier Research Group, the leading French independent pharmaceutical company, today announced that Osteologix has granted Servier an exclusive royalty bearing license to develop and commercialize NB S101 (strontium malonate) to treat post menopausal osteoporosis, other bone and joint disorders and dental indications worldwide, except in the U.S. NB S101 is an innovative molecule acting on both bone formation and bone resorption.

2 Aug 2010

Mental-health treatment could reduce pain in osteoarthritis patients: Study

How much pain osteoarthritis sufferers feel is directly related to their mental health, a new study by researchers at UC Davis School of Medicine has found. In the study, people with better mental health felt less pain, and people with worse mental health felt more.

31 Jul 2010

Intrinsic brain connectivity in fibromyalgia associated with chronic pain intensity

A recent study from researchers at Massachusetts General Hospital and University of Michigan provides the first direct evidence of linkage between elevated intrinsic (resting-state) brain connectivity and spontaneous pain intensity in patients with fibromyalgia (FM). This research shows an interaction of multiple brain networks, offering greater understanding of how pain arises. Details of the study appear online and in the August issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

30 Jul 2010

Immunosuppressive properties of TNF blockers may increase risk of malignancy in children

The Food and Drug Administration (FDA) received reports of malignancies in children using tumor necrosis factor (TNF) blockers, raising concerns of an associated risk and prompting an investigation. Researchers from the FDA set out to identify all reports of malignancy in children using infliximab, etanercept, and adalimumab and their report is published in the August issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology.

30 Jul 2010

Amgen second-quarter total revenue increases 2% to $3,804 million

Amgen reported adjusted earnings per share (EPS) of $1.38 for the second quarter of 2010, an increase of 7 percent compared to $1.29 for the second quarter of 2009. Adjusted net income increased 1 percent to $1,326 million for the second quarter of 2010 compared to $1,311 million for the second quarter of 2009.

30 Jul 2010

Resting brain activity associated with spontaneous fibromyalgia pain

29 Jul 2010

TNF blockers may increase the risk of malignancy in children

The Food and Drug Administration (FDA) received reports of malignancies in children using tumor necrosis factor a (TNF) blockers, raising concerns of an associated risk and prompting an investigation.

29 Jul 2010

Bioniche, Synerx announce FDA approval and launch of Isosulfan Blue Injection 1%

Bioniche Pharma, a leading developer and manufacturer of injectable pharmaceuticals, and Synerx Pharma, LLC announced today the FDA approval and launch of Isosulfan Blue Injection 1%.

29 Jul 2010

Alcohol consumption reduces risk of rheumatoid arthritis: Study

Drinking alcohol may reduce the severity of rheumatoid arthritis according to new research published today. It is the first time that this effect has been shown in humans. The study also finds that alcohol consumption reduces the risk of developing the disease, confirming the results of previous studies.

28 Jul 2010

Adherence improves long-term effectiveness of exercise therapy in OA patients

Patients with osteoarthritis (OA) of the knee or hip who adhere to the recommended home physical therapy exercises and physically active lifestyle experience more improvement in pain, physical function, and self-perceived effect according to a study from researchers in The Netherlands. Research also shows that maintenance of exercise behavior and physically active lifestyle after discharge of physical therapy improves the long-term effectiveness of exercise therapy in patients with knee or hip OA.

27 Jul 2010

Researchers reveal biological rationale for why corticosteroids help people with lupus

Researchers at UT Southwestern Medical Center have uncovered the biological rationale for why large doses of corticosteroids given repeatedly over several weeks may help individuals with lupus, a chronic inflammatory disease that affects more than 1 million people in the U.S.

27 Jul 2010

Athletes who undergo tissue transplant surgery for knee damage can return to sports: Study

Athletes with bone and cartilage knee damage who are treated with transplanted tissue can return to sports after surgery, according to a Hospital for Special Surgery study reported at the annual meeting of the American Orthopaedic Society for Sports Medicine, held July 15-18 in Providence, Rhode Island. The study (abstract 8970) overturns the widely held belief that patients who undergo this surgery do not return to athletics.

20 Jul 2010

Rottapharm Madaus, Selvita sign drug discovery services contract

Rottapharm Madaus and Selvita announced today signature of a services contract for delivery of drug discovery services. The aim of this project is to deliver to Rottapharm Madaus a set of designed and synthesized compounds, including their optimized synthesis route, which will have a therapeutic potential in an indicated area.

20 Jul 2010

Ronald Reagan UCLA Medical Center ranks first: U.S. News & World Report survey

Ronald Reagan UCLA Medical Center ranks as one of the top five American hospitals -- and the best hospital in the western United States for the 21st consecutive year -- according to a U.S. News & World Report survey that reviewed patient-outcomes data, reputation among physicians and other care-

17 Jul 2010

Rheumatology News and Research

Further Reading

ACR announces revised classification criteria for rheumatoid arthritis

CADTH Review Panel releases recommendations for Biologic Response Modifier Agents for Adults with RA

Ardea Biosciences second-quarter total revenues decline to $3.5 million

Incyte second-quarter total revenues increase to $49.8 million

Savient second-quarter net loss decreases to $5.0 million

International study of more than 60,000 women highlights additional risk associated with fractures

Osteologix grants Servier Research Group exclusive license to develop, commercialize NB S101

Mental-health treatment could reduce pain in osteoarthritis patients: Study

Intrinsic brain connectivity in fibromyalgia associated with chronic pain intensity

Immunosuppressive properties of TNF blockers may increase risk of malignancy in children

Amgen second-quarter total revenue increases 2% to $3,804 million

Resting brain activity associated with spontaneous fibromyalgia pain

TNF blockers may increase the risk of malignancy in children

Bioniche, Synerx announce FDA approval and launch of Isosulfan Blue Injection 1%

Alcohol consumption reduces risk of rheumatoid arthritis: Study

Adherence improves long-term effectiveness of exercise therapy in OA patients

Researchers reveal biological rationale for why corticosteroids help people with lupus

Athletes who undergo tissue transplant surgery for knee damage can return to sports: Study

Rottapharm Madaus, Selvita sign drug discovery services contract

Ronald Reagan UCLA Medical Center ranks first: U.S. News & World Report survey

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