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BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Rahm Gummuluru, PhD, associate professor of microbiology at Boston University School of Medicine, and Bjoern Reinhard, PhD, professor of chemistry at Boston University, have been awarded a Research Project Grant from the National Institutes of Allergy and Infectious Diseases/National Institute of Health.

5 Dec 2017

Shorter course of radiation may be preferred treatment for men with intermediate-risk prostate cancer

Prostate cancer is the most common cancer among males in the United States. Approximately, 180,000 men are diagnosed each year, and approximately 95 percent of these men have localized disease that is potentially curable.

5 Dec 2017

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Dangling a carrot for patients to take healthy steps: Does it work?

Patricia Alexander knew she needed a mammogram but just couldn't find the time. "Every time I made an appointment, something would come up," said Alexander, 53, who lives in Moreno Valley, Calif.

5 Dec 2017

Lithium chloride prevents neurological damage tied to fetal alcohol syndrome, mice study shows

A single dose of lithium chloride, a drug used to treat bipolar disease and aggression, blocks the sleep disturbances, memory loss, and learning problems tied to fetal alcohol syndrome, new experiments in mice show.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

WHO certifies elimination of mother-to-child HIV and syphilis transmission in six Caribbean territories

Anguilla, Antigua and Barbuda, Bermuda, Cayman Islands, Montserrat and Saint Kitts and Nevis were today certified by the World Health Organization as having eliminated mother-to-child transmission of HIV and syphilis.

5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Less invasive therapy relieves low back pain, study states

According to a study presented at the annual meeting of the Radiological Society of North America, most patients who had undergone image-guided pulsed radiofrequency treatment for sciatica and low back pain were pain-free.

4 Dec 2017

Study provides insights on mechanisms involved in tolerance after kidney transplantation

A new study provides insights on the mechanisms that allow an individual's immune system to accept, rather than reject, a donor kidney. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, point to markers that could be monitored to assess and track the health of organs following transplantation.

1 Dec 2017

Human sperm may hold potential to serve as biomarkers of future health

Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study by a Wayne State University School of Medicine research team.

1 Dec 2017

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Cancer therapies including radiation and chemotherapy seek to treat the disease by killing tumor cells. Now a team including researchers at Beth Israel Deaconess Medical Center have shown that the dead and dying cancer cells generated by chemotherapy and targeted cancer therapy paradoxically trigger inflammation that promotes aggressive tumor growth.

1 Dec 2017

Smartphone addiction may be responsible for an imbalance in the brain, study says

A new study presented yesterday at the annual meeting of the Radiological Society of North America (RSNA) identified an imbalance in the brain chemistry of young people who are addicted to smartphones and the internet.

1 Dec 2017

Orchard Therapeutics opens new facility for technical operations in San Francisco Bay area

Orchard Therapeutics, a clinical-stage biotechnology company dedicated to transforming the lives of patients with rare disorders through innovative gene therapies, today announced the opening of a second facility for technical operations in the San Francisco Bay Area.

1 Dec 2017

New targeted treatment could benefit patients with certain pancreatic tumors

Researchers at the University of Cincinnati College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage--a direct result of the tumor.

1 Dec 2017

Therapy News and Research

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Shorter course of radiation may be preferred treatment for men with intermediate-risk prostate cancer

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Dangling a carrot for patients to take healthy steps: Does it work?

Lithium chloride prevents neurological damage tied to fetal alcohol syndrome, mice study shows

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

WHO certifies elimination of mother-to-child HIV and syphilis transmission in six Caribbean territories

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Less invasive therapy relieves low back pain, study states

Study provides insights on mechanisms involved in tolerance after kidney transplantation

Human sperm may hold potential to serve as biomarkers of future health

Chemotherapy-generated debris from dead and dying cancer cells can stimulate tumor growth

Smartphone addiction may be responsible for an imbalance in the brain, study says

Orchard Therapeutics opens new facility for technical operations in San Francisco Bay area

New targeted treatment could benefit patients with certain pancreatic tumors

Novel drug combination could enhance immunotherapy responses in patients with lung cancer

CBT and mindfulness training can reverse negative psychological effects of prison time

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

Drug that stimulates neuron pruning promotes goal-directed behavior in mice

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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