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Fibrin may be new target for Alzheimer's drugs

Despite the rapid rise of Alzheimer's disease - the Alzheimer's Association predicts as many as 7.7 million cases by 2030 - there are no preventative treatments available, few in the pharmaceutical pipeline, and those drugs being developed all share the same two molecular targets.

15 Aug 2007

Alarm over death in clinical trial for arthritis therapy

The death of a woman taking part in a clinical trial for an arthritis therapy has set alarm bells ringing in the United States.

12 Aug 2007

Green tea may help treat psoriasis

Green tea which is already recommended for its cancer-fighting properties, also appears to be a promising new treatment for skin disorders such as psoriasis, lupus-induced lesions and dandruff.

12 Aug 2007

Researchers discover how Bcl-3 protein stops inflammation

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

12 Aug 2007

Sex steroids, platelet aggregation and inflammation

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein. Despite the fact that the disorder is rare, it increases exponentially during menopause and can be deadly.

11 Aug 2007

New pathway for inflammation-induced cancer

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at The University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell .

11 Aug 2007

New approach to assessing clot risk in menopausal women

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein.

9 Aug 2007

Obesity linked to hyperparathyroidism in chronic kidney disease

For patients with chronic kidney disease (CKD), the risk of elevated levels of parathyroid hormone (PTH), or hyperparathyroidism a significant complication that increases the risk of cardiovascular problems and death increases along with body weight, reports a study in the September Clinical Journal of the American Society of Nephrology.

9 Aug 2007

New test to detect early stage liver cancer

Cancer of the liver is very difficult to detect, and it is a major cause of death in Asia and Africa, with rising incidence in Western countries as well.

9 Aug 2007

Prophylaxis effective at preventing joint bleeds and preserving joint function and structure in young boys with hemophilia A

According to a new landmark study published in The New England Journal of Medicine, infusions of clotting factor VIII used preventively can significantly reduce the risk of developing joint damage associated with joint bleeding in young children with hemophilia A.

9 Aug 2007

Inflammation from bacterial infections linked to preterm births and deaths

New findings from the mouse study holds potential to develop ways to curb the emotional and economic toll on families that lose babies to preterm labor and fetal death, said Han, a member of from the department of periodontics.

9 Aug 2007

Bcl-3 protein regulates inflammation by blocking ubiquitination

8 Aug 2007

E. coli bacteria linked to Crohn's disease

A team of Cornell University scientists from the College of Veterinary Medicine, Weill Cornell Medical College and the College of Agriculture and Life Sciences have discovered that a novel group of E. coli bacteria, containing genes similar to those described in uropathogenic and avian pathogenic E. coli and enteropathogenic bacteria such as salmonella, cholera, bubonic plague, is associated with intestinal inflammation in patients with Crohn's disease in their research paper published July 12 by the ISME Journal: Multidisciplinary Journal of Microbial Ecology.

8 Aug 2007

Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

Green tea holds promise for psoriasis and dandruff

Green tea could hold promise as a new treatment for skin disorders such as psoriasis and dandruff, Medical College of Georgia researchers say.

7 Aug 2007

What causes rosacea?

Doctors can describe the symptoms of rosacea, a common inflammatory skin disease that causes facial redness and affects nearly 14 million Americans.

6 Aug 2007

How the brain produces fever responses during infections

With the finding that fever is produced by the action of a hormone on a specific site in the brain, scientists have answered a key question as to how this adaptive function helps to protect the body during bacterial infection and other types of illness.

6 Aug 2007