Antigen News and Research

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Trial reveals effectiveness of axi-cel as first-line treatment for high-risk lymphoma

Results from the ZUMA-12 trial led by researchers at The University of Texas MD Anderson Cancer Center showed that first-line treatment with axicabtagene ciloleucel (axi-cel), a chimeric antigen receptor (CAR) T cell therapy, achieved a high rate of complete response in patients with high-risk large B-cell lymphoma (LBCL).

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

IU researchers exploring new ways to treat seasonal or intermittent asthma

Researchers from Indiana University School of Medicine Department of Microbiology and Immunology are studying new ways to treat seasonal or intermittent asthma.

21 Mar 2022

Safety and antibody responses to COVID-19 vaccines in an older community

Researchers evaluated the antibody responses in an older cohort following COVID-19 vaccination and compared them to a younger cohort.

21 Mar 2022

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

A team of scientists from Turkey has recently evaluated the diversity and composition of gut microbiota in children diagnosed with multisystem inflammatory syndrome (MIS-C) and acute coronavirus disease 2019 (COVID-19). They have observed significant alteration in the gut microbiota composition in children with MIS-C. These changes are associated with autoimmunity, metabolic dysfunction, and obesity.

21 Mar 2022

Study links the usage of oral polio vaccines with lower incidence of COVID-19

A study published in the journal PLOS ONE showed how countries using oral polio vaccine have a lower incidence of coronavirus disease (COVID-19) when compared to those using inactivated polio vaccine – suggesting that the oral vaccine may either prevent the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the individual level or slow down the transmission in the community.

21 Mar 2022

Acidity of expiratory aerosols influences infectivity of SARS-CoV-2

Researchers provide insight on the potentially significant impact of aerosol pH on the transmission of SARS-CoV-2.

20 Mar 2022

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers assessed the impact of recombinant accessory protein-deficient severe acute respiratory syndrome coronavirus 2 immunization against SARS-CoV-2 transmission and disease severity.

18 Mar 2022

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Researchers analyzed the innate and adaptive responses to the mRNA-based BNT162b2 COVID-19 vaccine in mice.

18 Mar 2022

Study explores SARS-CoV-2 spike epitope with potent and broad neutralization

Researchers reported an epitope with high potency and breadth and demonstrated that a therapeutic antibody directed at this site neutralizes all SARS-CoV-2 variants.

18 Mar 2022

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

Researchers investigated whether small airway diseases are present following acute SARS-CoV-2 infection.

18 Mar 2022

COVID-19-related hospitalization among infants and young children in the US

Researchers investigated COVID-19-associated hospitalization among children and infants aged zero to four years in the United States during March 2020 and February 2022.

18 Mar 2022

New approach radically increases the success of breast cancer immunotherapy

A study published in the journal Nature Cancer, carried out within the Cancer Programme at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan Albanell, with the participation of international centers, has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumors, triple-negative breast cancer.

17 Mar 2022

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Researchers investigate innate and adaptive immune responses at both the early and late stages of SARS-CoV-2 infection.

17 Mar 2022

Rapid and cheap test for dysosmia in COVID-19

A new study discusses the potential utility of using paired ampules of n-butanol to screen for COVID-19 and detect those at greater risk for severe illness.

17 Mar 2022

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Researchers assessed the safety profile and immunogenicity of a heterologous NVSI-06-08 boost against SARS-CoV-2 variants in individuals doubly vaccinated with the inactivated vaccine BBIBP-CorV.

17 Mar 2022

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

An inhalable 'aerogel' loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice, according to new research conducted at Penn State.

16 Mar 2022

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

While many people in wealthier countries have been vaccinated against Covid-19, there is still a need for vaccination in much of the world.

16 Mar 2022

Highly sensitive PCR test for COVID-19 receives FDA emergency use authorization

A new highly sensitive, easy-to-use test for COVID-19 that requires a single swab and 15 minutes has received emergency use authorization (EUA) status from the U.S. Food and Drug Administration (FDA).

16 Mar 2022

New findings could change treatment practice and lengthen survival for men with pN1 prostate cancer

Men with microscopic evidence of prostate cancer spreading to their pelvic lymph nodes (LNs) following the surgical resection of the prostate and pelvic lymph nodes (LN) are at a very high risk of dying from prostate cancer. Pelvic LN radiation therapy (RT) is a potentially curative treatment.

15 Mar 2022

Antigen News and Research

Trial reveals effectiveness of axi-cel as first-line treatment for high-risk lymphoma

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

IU researchers exploring new ways to treat seasonal or intermittent asthma

Safety and antibody responses to COVID-19 vaccines in an older community

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

Study links the usage of oral polio vaccines with lower incidence of COVID-19

Acidity of expiratory aerosols influences infectivity of SARS-CoV-2

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Innate and adaptive immune responses to BNT162b2 vaccination in mice

Study explores SARS-CoV-2 spike epitope with potent and broad neutralization

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

COVID-19-related hospitalization among infants and young children in the US

New approach radically increases the success of breast cancer immunotherapy

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Rapid and cheap test for dysosmia in COVID-19

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

Highly sensitive PCR test for COVID-19 receives FDA emergency use authorization

New findings could change treatment practice and lengthen survival for men with pN1 prostate cancer

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