Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Exploring the biomarker profiles in severe COVID-19

In new research, researchers estimated the D-dimer levels and characterized lymphocyte subsets and cytokine profiles in severe coronavirus disease 2019 (COVID-19) patients.

7 Oct 2022

Study links pancreatic cancer survival outcomes with arrangement of immune cells in tumors

Researchers from Johns Hopkins Medicine have discovered that the organization of different types of immune cells within pancreatic tumors is associated with how well patients with pancreatic cancer respond to treatment and how long they survive.

6 Oct 2022

Northwestern Medicine scientists discover new gene target for aggressive lung cancer

Northwestern Medicine scientists have identified and described a new gene that is responsible for activating an aggressive subtype of small-cell lung cancer, the P subtype, for which there is no current effective treatment.

5 Oct 2022

NYU researchers collaborate with FDA to design first-ever stroke rehabilitation regulatory science tool

Stroke is the leading cause of age-related motor disabilities and is becoming more prevalent in younger populations as well.

5 Oct 2022

Smartphone App could help advance the early detection of Parkinson's disease and severe COVID-19

A new screening test App could help advance the early detection of Parkinson's disease and severe COVID-19, improving the management of these illnesses.

5 Oct 2022

Decline in specific protein levels linked to Alzheimer’s disease, not buildup of amyloid plaques

New research from the University of Cincinnati bolsters a hypothesis that Alzheimer's disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been recently called into question.

5 Oct 2022

Study investigates associations between potential endocrine-disrupting chemicals and female fertility

About one in six women of reproductive age face difficulties in conceiving or carrying a pregnancy to term. Although there has been a global increase in the use of assisted reproductive technologies (ARTs), the success rate of live birth has remained almost the same.

3 Oct 2022

Collaboration aims to investigate ARTIDIS technology as novel treatment-optimization tool for solid tumors

The University of Texas MD Anderson Cancer Center and ARTIDIS AG today announced a strategic alliance to investigate ARTIDIS technology as a novel treatment-optimization tool for patients with solid tumors in several distinct indications.

3 Oct 2022

Plasma proteome signature predictive of occurrence of persistent symptoms following SARS-CoV-2 infection

In a new study, researchers performed a proteomic multiple-reaction monitoring analysis of 91 pre-selected proteins using the plasma samples of 156 healthcare workers (HCW) in the United Kingdom (UK).

30 Sep 2022

New algorithm may help predict the risk of Alzheimer's dementia

When people participate in studies of aging, they often want to know what their individual risks of developing dementia from Alzheimer's disease are. Washington University researchers have developed an algorithm that can help provide them with information about what their risks may be.

30 Sep 2022

Many diverse nanopore research directions and applications beyond DNA sequencing

In a recent Nature Nanotechnology study, researchers describe diverse applications of nanopore-based technology beyond deoxyribonucleic acid (DNA) sequencing. More specifically, the current research focuses on the advancements of this technology within chemistry, biophysics, and nanoscience.

29 Sep 2022

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

A novel PET radiotracer can accurately assess the presence of a biomarker that indicates the level of tumor aggressiveness in neuroendocrine neoplasms (NENs).

28 Sep 2022

Study aims to understand how SARS-CoV-2 affects the brain long-term

Researchers formulate a method to identify the molecular and systemic factors linking COVID-19 to short- and long-term neurologic illness.

28 Sep 2022

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study led by Oregon State University suggests.

28 Sep 2022

Association of self-reported chronic fatigue and retinal microcirculation in post-COVID-19 syndrome patients

Researchers investigated the potential association between self-reported chronic fatigue and retinal microcirculation among post-COVID-19 syndrome patients.

27 Sep 2022

What are the neuropsychiatric effects of SARS-CoV-2 infection?

Researchers investigated cognitive deficits associated with acute SARS-CoV-2 infection.

27 Sep 2022

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC).

22 Sep 2022

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

In a new study, researchers designed a liquid biomarker panel consisting of macrophage and monocyte-related soluble factors and circulating spike proteins to understand profiles of immune dysregulation in patients with post-acute sequelae of COVID-19.

22 Sep 2022

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

In a new study, a team of researchers explored the effect of immune checkpoint blockade (ICB)-induced expansion of age-associated B cells (ABCs) on COVID-19 vaccine-derived humoral immunity in patients with cancer and inborn errors of immunity (IEI).

22 Sep 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

Biomarker News and Research

Further Reading

Exploring the biomarker profiles in severe COVID-19

Study links pancreatic cancer survival outcomes with arrangement of immune cells in tumors

Northwestern Medicine scientists discover new gene target for aggressive lung cancer

NYU researchers collaborate with FDA to design first-ever stroke rehabilitation regulatory science tool

Smartphone App could help advance the early detection of Parkinson's disease and severe COVID-19

Decline in specific protein levels linked to Alzheimer’s disease, not buildup of amyloid plaques

Study investigates associations between potential endocrine-disrupting chemicals and female fertility

Collaboration aims to investigate ARTIDIS technology as novel treatment-optimization tool for solid tumors

Plasma proteome signature predictive of occurrence of persistent symptoms following SARS-CoV-2 infection

New algorithm may help predict the risk of Alzheimer's dementia

Many diverse nanopore research directions and applications beyond DNA sequencing

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

Study aims to understand how SARS-CoV-2 affects the brain long-term

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Association of self-reported chronic fatigue and retinal microcirculation in post-COVID-19 syndrome patients

What are the neuropsychiatric effects of SARS-CoV-2 infection?

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Study using circulating spike protein and macrophage dysregulation liquid biomarkers reveals heterogeneity in PASC

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

New genetically-targeted MND therapy could be a turning point for patient care

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