Cell Death News and Research

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Head-to-head comparison of three breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form--which tests positive for hormone receptors (HR+) and negative for the HER2 receptor--usually respond well to treatment.

23 Aug 2019

New cannabis-based drug shows promise for pancreatic cancer

Cancer of the pancreas is a particularly deadly cancer, claiming over 90% of its victims within 5 years from diagnosis. It resists most standard therapies, including surgery, chemotherapy, radiation therapy, immunotherapy and targeted therapy, and metastasizes early, often before being diagnosed. A cure is possible only with very localized tumors.

22 Aug 2019

Researchers analyze precise mechanism of binding reaction in PUVA therapy

The term 'PUVA' stands for 'psoralen' and 'UV-A radiation'. Psoralens are natural plant-based compounds that can be extracted from umbelliferous plants such as giant hogweeds.

21 Aug 2019

New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019

Study uncovers potential new treatment approach for lung cancer

Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway.

19 Aug 2019

Study shows synergistic effects of drugs that inhibit cell division in pancreatic cancer

Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread.

19 Aug 2019

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the elusive cellular actions leading to disease onset.

14 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Researchers examine how superbug fights last-resort antibiotics

Antibiotic resistance is one of the biggest threats to global health, food security, and development today. A new study shows how superbugs adapt to combat 'last-resort antibiotics'.

13 Aug 2019

Bile pigment may play an unexpected role in protecting the brain

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting brain cells from damage from oxidative stress.

From Johns Hopkins Medicine 13 Aug 2019

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier — the normally tight border that prevents harmful molecules in the bloodstream from entering the brain.

13 Aug 2019

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons.

13 Aug 2019

Antibody may help the immune system fight sepsis-related fungal infections

An antibody that blocks the "programmed cell death" pathway may help the immune system fight off sepsis-related fungal infections, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

12 Aug 2019

Study shows how cigarette smoke drives tumor aggressiveness in head and neck cancer

Head and neck cancer is the sixth most common cancer in the world. The vast majority of cases are head and neck squamous cell carcinoma, a type of cancer that arises in the outer layer of the skin and mucous membranes of the mouth, nose and throat.

8 Aug 2019

New method to enhance heart-attack repair using stem cell-derived cardiomyocytes

The heart cannot regenerate muscle tissue after a heart attack has killed part of the muscle wall. That dead tissue can strain surrounding muscle, leading to a lethal heart enlargement.

8 Aug 2019

New research explains why some cancers don't respond to immunotherapy

New research has uncovered a mechanism thought to explain why some cancers don't respond to a widely used form of immunotherapy called "checkpoint inhibitors" or anti-PD-1.

6 Aug 2019

Sheffield academic receives funding to protect brain cells affected by Parkinson's

A Sheffield academic has been awarded £100,000 of funding by the Virtual Biotech Programme - the drug development arm of charity Parkinson's UK - to develop a new treatment that could protect brain cells affected by Parkinson's disease, potentially slowing, or stopping its progression for the first time.

6 Aug 2019

Researchers show how microorganisms protect themselves against free radicals

There are numerous different scenarios in which microorganisms are exposed to highly reactive molecules known as free radicals.

5 Aug 2019

GW Cancer Center selected as first global clinical trial site for high risk cutaneous squamous cell carcinoma

Under the leadership of Vishal A. Patel, MD, FAAD, FACMS, director of the Cutaneous Oncology Program at the George Washington University Cancer Center, the GW Cancer Center was selected as the first global site for a clinical trial for patients with high-risk cutaneous squamous cell carcinoma.

3 Aug 2019

Antimicrobial peptides that help protect against infection defend against cancer

An antimicrobial agent called Defensin kills tumor cells and shrinks tumor size in fruit flies, with help from a pathway that flags the cells for destruction.

31 Jul 2019

Cell Death News and Research

Head-to-head comparison of three breast cancer drugs reveals important differences

New cannabis-based drug shows promise for pancreatic cancer

Researchers analyze precise mechanism of binding reaction in PUVA therapy

New circulating immune cell could help predict type 1 diabetes risk

Study uncovers potential new treatment approach for lung cancer

Study shows synergistic effects of drugs that inhibit cell division in pancreatic cancer

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

Researchers identify new transmembrane protein as chloride ion channel

Researchers examine how superbug fights last-resort antibiotics

Bile pigment may play an unexpected role in protecting the brain

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Antibody may help the immune system fight sepsis-related fungal infections

Study shows how cigarette smoke drives tumor aggressiveness in head and neck cancer

New method to enhance heart-attack repair using stem cell-derived cardiomyocytes

New research explains why some cancers don't respond to immunotherapy

Sheffield academic receives funding to protect brain cells affected by Parkinson's

Researchers show how microorganisms protect themselves against free radicals

GW Cancer Center selected as first global clinical trial site for high risk cutaneous squamous cell carcinoma

Antimicrobial peptides that help protect against infection defend against cancer

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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