Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Masked hypertension in CKD children can increase risk of heart disease

Many children with chronic kidney disease (CKD) who show normal blood pressure readings at the doctor's office have high blood pressure when tested at home, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

13 Nov 2009

UT Southwestern Medical Center awarded $42M for basic and patient-oriented research

UT Southwestern Medical Center has been awarded more than $42 million to date for basic and patient-oriented research from the American Recovery and Reinvestment Act of 2009, the $787 billion stimulus package President Barack Obama signed into law in February.

13 Nov 2009

EMS Solutions provides free resources to help companies tackle this year's H1N1 flu pandemic

Emergency Management & Safety Solutions (EMS Solutions), the crisis planner for many Fortune 100 companies, international government agencies and large non-profit organizations, is providing free resources to help companies better prepare for and prevent transmission of this year's H1N1 flu pandemic. Today, over 180 countries have experienced the H1N1 virus outbreak and approximately 6,500 people have died -- including over 1,500 in North America, according to the European Center for Disease Prevention and Control.

12 Nov 2009

Pan-African conference to focus on the rapid growth of diabetes in Africa

The Republic of Mauritius in collaboration with the World Health Organization Afro Region and the International Diabetes Federation (IDF) today opened an International Conference on Diabetes & Associated Diseases in Port Louis, Mauritius to highlight their concern about the rapid growth of the diabetes epidemic throughout Africa. The conference will run from November 12 and end on November 14 – World Diabetes Day.

11 Nov 2009

Chronic kidney disease on the rise; preventive testing is critical for diabetic patients

New data confirms the rate of chronic kidney disease is inching upward, keeping pace with the rising rates of diabetes. In late September, the U.S. Renal Data System published its 2009 Annual Data report, which shows the incidence of chronic kidney disease in the U.S. Medicare population is now 9.8%, up from 8.7% reported in last year’s data analysis.

11 Nov 2009

Financial results for third-quarter 2009 announced by PLC Systems

PLC Systems Inc., a company focused on innovative cardiac and vascular medical device-based technologies, today reported financial results for the three and nine month periods ended September 30, 2009.

11 Nov 2009

Baxter International lauds new Medicare education benefit for chronic kidney disease patients

Baxter International Inc. commends the Centers for Medicare and Medicaid Services (CMS) on announcing implementation plans for a new Medicare benefit that will provide Stage 4 chronic kidney disease patients with coverage for up to six sessions explaining their treatment options, such as transplantation, home peritoneal dialysis (PD), home hemodialysis (HHD) or clinic-based hemodialysis (HD).

From Baxter International Inc. 10 Nov 2009

Research reveals new biological function of polycystins in regulating pressure sensing

What is the role of proteins called polycystins in patients with polycystic kidney disease? A team of researchers from CNRS and INSERM, led by Eric Honoré from the Institut de Pharmacologie Moléculaire et Cellulaire (IPMC, Université de Nice Sophia Antipolis/CNRS) has elucidated the molecular and cellular mechanisms linked to polycystin malfunctions that cause this common hereditary disease.

6 Nov 2009

Endothelin increases T cells in the kidneys leading to renal injury

A key player in a cascade that likely begins with stress and leads to high blood pressure and kidney damage has been identified by researchers who say the finding may lead to better ways to control both.

6 Nov 2009

Declining kidney function linked to higher risk of heart failure in individuals with or without kidney disease

Declining kidney function is linked to a higher risk of heart failure, heart attack, peripheral arterial disease, and early death in individuals with or without kidney disease, according to a pair of studies appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

6 Nov 2009

Higher levels of phosphorus in blood linked to increased calcification of coronary arteries, says study

Higher levels of phosphorus in the blood are linked to increased calcification of the coronary arteries— a key marker of heart disease risk, according to a study in an upcoming issue of Clinical Journal of the American Society of Nephrology (CJASN). "This may help to explain why even early-stage chronic kidney disease (CKD) is associated with increased cardiovascular risk that is not otherwise explained by traditional risk factors," comments Katherine R. Tuttle, MD (Providence Medical Research Center, Spokane, WA).

6 Nov 2009

Study demonstrates potential of human Serum Amyloid P to block very aggressive fibrotic pathology

Promedior, Inc., a leader in the development of novel therapeutics for the treatment of fibrotic diseases and tissue remodeling, announced today the publication of results from preclinical studies demonstrating that human Serum Amyloid P (hSAP) potently inhibited fibrosis in two independent model systems of kidney fibrosis.

5 Nov 2009

Avoiding foods high in AGE toxins can reduce inflammation and restore the body's natural defenses

Researchers from Mount Sinai School of Medicine report that cutting back on the consumption of processed and fried foods, which are high in toxins called Advanced Glycation End products (AGEs), can reduce inflammation and actually help restore the body's natural defenses regardless of age or health status. These benefits are present even without changing caloric or nutrient intake.

4 Nov 2009

Cutting back on the consumption of AGEs can reduce inflammation, report researchers

4 Nov 2009

New molecular pathway for preventing potassium from being excreted normally through kidney identified

Researchers at the University of Maryland School of Medicine have made an important discovery about why potassium builds up to dangerous levels in the bloodstream, a relatively common medical problem that affects about eight percent of hospitalized patients.

4 Nov 2009

FDA updates Byetta prescribing information following reports of kidney problems

The U.S. Food and Drug Administration today acted on new safety information about possible kidney function problems, including kidney failure, in patients taking Byetta (exenatide), a drug used to treat Type 2 diabetes.

3 Nov 2009

Women at particular risk of their primary care physicians delaying diagnosis of CKD: Study

Woman are at particular risk of their primary care physicians delaying diagnosis of chronic kidney disease (CKD), according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, California. The findings suggest that educating practitioners about CKD could increase the timely diagnosis of CKD, thereby leading to improvements in care to patients and savings in Medicare dollars.

2 Nov 2009

Dialysis patients with low body fat face high mortality rate

Dialysis patients with low body fat are at increased risk of death-even compared to patients at the highest level of body fat percentage, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego.

2 Nov 2009

Combination of inhibitor and antioxidants may help prevent diabetes complications

In diabetes patients, high blood glucose levels can end up killing certain cells in the eyes and kidneys, which is why diabetes is the leading cause of adult blindness and of kidney failure. Years ago, scientists identified one main route for this destruction—high glucose produces oxidative stress through the NF-kB molecular pathway—but success has been elusive for drugs targeting that pathway.

2 Nov 2009

High sodium diet and artificially sweetened soda linked to kidney function decline

Individuals who consume a diet high in sodium or artificially sweetened drinks are more likely to experience a decline in kidney function, according to two papers being presented at the American Society of Nephrology's annual meeting in San Diego, California.

2 Nov 2009

Nephropathy News and Research

Further Reading

Masked hypertension in CKD children can increase risk of heart disease

UT Southwestern Medical Center awarded $42M for basic and patient-oriented research

EMS Solutions provides free resources to help companies tackle this year's H1N1 flu pandemic

Pan-African conference to focus on the rapid growth of diabetes in Africa

Chronic kidney disease on the rise; preventive testing is critical for diabetic patients

Financial results for third-quarter 2009 announced by PLC Systems

Baxter International lauds new Medicare education benefit for chronic kidney disease patients

Research reveals new biological function of polycystins in regulating pressure sensing

Endothelin increases T cells in the kidneys leading to renal injury

Declining kidney function linked to higher risk of heart failure in individuals with or without kidney disease

Higher levels of phosphorus in blood linked to increased calcification of coronary arteries, says study

Study demonstrates potential of human Serum Amyloid P to block very aggressive fibrotic pathology

Avoiding foods high in AGE toxins can reduce inflammation and restore the body's natural defenses

Cutting back on the consumption of AGEs can reduce inflammation, report researchers

New molecular pathway for preventing potassium from being excreted normally through kidney identified

FDA updates Byetta prescribing information following reports of kidney problems

Women at particular risk of their primary care physicians delaying diagnosis of CKD: Study

Dialysis patients with low body fat face high mortality rate

Combination of inhibitor and antioxidants may help prevent diabetes complications

High sodium diet and artificially sweetened soda linked to kidney function decline

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