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Novel promising biomarker correlates with the severity of facioscapulohumeral muscular dystrophy

There is currently no effective treatment for facioscapulohumeral muscular dystrophy (FSHD), one of the most common neuromuscular diseases, which is caused by an abnormal expression of the transcription factor DUX4.

15 Feb 2022

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients, according to findings published in Proceedings of the National Academy of Sciences.

15 Feb 2022

South African population reveal durable protection by prior infection against pre-Omicron variants

A recent study explored the buildup of immunity developed post-SARS-CoV-2 infection in African people and the impact of SARS-CoV-2 Omicron VOC on the COVID-19 pandemic.

15 Feb 2022

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

First survey on Omicron BA.2 in France

In a recent study posted to the medRxiv* preprint server, researchers described the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 21L/BA.2 Omicron variant in south-eastern France.

14 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Researchers reported the development and validation of a two-reaction multiplex reverse transcription-quantitative polymerase chain reaction genotyping strategy that distinguishes SARS-CoV-2 variants of concern.

14 Feb 2022

Study explores the gut microbiome of COVID-19 patients

Researchers investigated the changes in the gut microbiome and the presence of SARS-CoV-2 in stool samples of COVID-19 patients.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Spatial transcriptomics-driven gene mapping offers new insights into inflammatory bowel disease

Using a technique called spatial transcriptomics, researchers at Karolinska Institutet in Sweden have analyzed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed.

12 Feb 2022

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

Transcription News and Research

Novel promising biomarker correlates with the severity of facioscapulohumeral muscular dystrophy

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

South African population reveal durable protection by prior infection against pre-Omicron variants

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

First survey on Omicron BA.2 in France

RNA capping mechanism of SARS-CoV-2 unveiled

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Study explores the gut microbiome of COVID-19 patients

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Spatial transcriptomics-driven gene mapping offers new insights into inflammatory bowel disease

First unbiased proteome scale study expands the number of known transcriptional activators

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

New reagent-free SARS-CoV-2 detection technique based on machine learning and Raman spectroscopy

Study explores wastewater surveillance of US military installations to mitigate the spread of SARS-CoV-2

Innate immune specificity is driven by the nervous system, study suggests

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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