Translation News and Research

RSS

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

The National Heart, Lung and Blood Institute of the National Institutes of Health has awarded a five-year grant of $15.6 million to Karina Yazdanbakhsh, PhD, of New York Blood Center’s Lindsley F. Kimball Research Institute, to lead a collaborative research program studying the consequences of transfusions in patients with sickle cell disease and developing strategies to optimize transfusion management for this patient group.

21 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

Shielding stem cells with novel biomaterial can reduce heart attack damage

Bioengineers and surgeons from Rice University and Baylor College of Medicine (BCM) have shown that shielding stem cells with a novel biomaterial improves the cells' ability to heal heart injuries caused by heart attacks.

18 Aug 2020

Historic study that evidenced the benefits of anti-COVID steroids could have saved lives

A study from early in the global coronavirus pandemic that evidenced the benefits of using steroids to combat COVID-19 in severely ill patients could have saved lives, according to the University of Huddersfield researchers involved.

18 Aug 2020

Non-sustained research on emerging infectious diseases endangers pandemic responses

Lack of Continuing Research Into Infectious Disease Epidemics Endangers Pandemic Responses, According to Ben-Gurion University Researchers

18 Aug 2020

SARS-CoV-2 spike pocket is a putative target for antiviral design

In a methodologically rigorous study, researchers from the University of Oxford have recently shown how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein harbors a lipid-binding pocket which modulates the stability of the prefusion trimer and provides conformational shielding from antibodies. Their findings are currently freely available on the bioRxiv* preprint server.

16 Aug 2020

Scientists hope to find clues about how life emerged by tinkering with its oldest components

"I'm fascinated with life, and that's why I want to break it."

15 Aug 2020

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Genes on the X chromosome may be key to melanoma survival advantage in females

Centenary Institute scientists have discovered that genes on the X chromosome may be key to the improved survival rates of females with melanoma–as compared to their male counterparts.

13 Aug 2020

Researchers develop new tool that acts like colonoscopy

Your gut bacteria could say a lot about you, such as why you're diabetic or how you respond to certain drugs. But scientists can see only so much of the gastrointestinal tract to study the role of gut bacteria in your health.

13 Aug 2020

Oxygen-deprived breast cancer cells send out messages that promote cancer progression

According to a study by The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells.

11 Aug 2020

As crisis grows, farms try to balance health of field workers and food supply

It's a busy time for the tomato-producing farms in this part of the state. Farms have staffed up with hundreds of workers, most of whom are Latino.

10 Aug 2020

European Commission approves first drug for hepatitis D

What started off as basic research 25 years ago has now lead to a successfully approved drug: The entry blocker bulevirtide (brand name Hepcludex, formerly known as Myrcludex B), jointly developed by researchers from Heidelberg University Hospital (UKHD) and the Medical Faculty of Heidelberg, the DZIF and other partners, has now been approved by the European Commission.

5 Aug 2020

Scientists develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas

5 Aug 2020

Researchers to develop oil-based system to clean commercial nut paste facilities

From home bakers to commercial food producers, everyone knows that cleaning peanut butter off utensils and out of bowls is a tricky, sticky proposition.

5 Aug 2020

New computational model can help determine drug viability

About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn's disease, end up becoming resistant or unresponsive to it.

5 Aug 2020

NCI gives 'exceptional' rating to Penn's Abramson Cancer Center

The National Cancer Institute has once again rated the Abramson Cancer Center of the University of Pennsylvania as "exceptional," the highest possible rating for an NCI-designated comprehensive cancer center.

4 Aug 2020

Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

By exploiting the tools of synthetic biology, the researchers from Turkey have successfully developed a de novo riboregulator system for rapidly detecting the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic material. Their paper is currently available on medRxiv preprint server.

2 Aug 2020

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Researchers led by a team at Rosalind Franklin University of Medicine and Science have devised a new therapeutic approach to treating a rare but deadly neurodegenerative genetic disease in children.

31 Jul 2020

Translation News and Research

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

Using engineered off-the-shelf therapeutic T cells to fight cancer

Shielding stem cells with novel biomaterial can reduce heart attack damage

Historic study that evidenced the benefits of anti-COVID steroids could have saved lives

Non-sustained research on emerging infectious diseases endangers pandemic responses

SARS-CoV-2 spike pocket is a putative target for antiviral design

Scientists hope to find clues about how life emerged by tinkering with its oldest components

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

Genes on the X chromosome may be key to melanoma survival advantage in females

Researchers develop new tool that acts like colonoscopy

Oxygen-deprived breast cancer cells send out messages that promote cancer progression

As crisis grows, farms try to balance health of field workers and food supply

European Commission approves first drug for hepatitis D

Scientists develop new models to study molecular characteristics of lung and pancreatic cancers

Researchers to develop oil-based system to clean commercial nut paste facilities

New computational model can help determine drug viability

NCI gives 'exceptional' rating to Penn's Abramson Cancer Center

Researchers develop scalable strategy to find novel molecular glue degraders

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News