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Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

Cutaneous angiosarcoma is a rare, highly aggressive skin tumor found primarily on the scalps of older White people, but based on new research from the University of North Carolina School of Medicine and the Lineberger Comprehensive Cancer Center, immunotherapies effective against lung cancer and melanoma may also work against this cancer.

18 Nov 2020

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

A new study conducted by a team of researchers at Johns Hopkins University, USA, has observed how pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show stunted antiviral immune responses.

18 Nov 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

COVID-19's harmful neurological effects are more common in patients with hypertension, diabetes

Some patients with COVID-19 are at higher risk of neurological complications like bleeding in the brain and stroke, according to a study being presented at the annual meeting of the Radiological Society of North America.

18 Nov 2020

Government-funded scientists laid the groundwork for billion-dollar vaccines

When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic.

18 Nov 2020

Diabetes and hypertension may increase the risk of COVID-19 brain complications

New data has revealed those with type 2 diabetes and hypertension are at an increased risk of neurological complications following infection with COVID-19.

18 Nov 2020

Algorithm-driven program improves cholesterol, blood pressure levels

Using a remotely-delivered, algorithm-driven program for disease management, patients experienced significant improvement in cholesterol and blood pressure levels, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

18 Nov 2020

People with heart disease can receive high-dose or standard-dose flu vaccines for protection

People with heart disease can receive either the high-dose or standard-dose flu vaccines for protection from heart or lung-related deaths or hospitalizations, according to late breaking research presented today at the American Heart Association's Scientific Sessions 2020.

18 Nov 2020

Children in Melbourne family developed COVID-19 immune response after exposure to virus

Children in a Melbourne family developed a COVID-19 immune response after chronic exposure to the SARS-CoV-2 virus from their parents, a new case report has found.

18 Nov 2020

Noninvasive, self-administered digital tool helps assess risk for preterm delivery

Women who are intending to become pregnant or who have just found out they are pregnant can quickly learn of their risk for preterm birth with a noninvasive, self-administered digital tool called PopNatal.

18 Nov 2020

Study: e-cigarette users have increased susceptibility to flu, COVID-19

In a controlled study of smokers, nonsmokers, and e-cigarette users, University of North Carolina School of Medicine researchers found that e-cigarette users exhibited significantly altered immune responses to a model of influenza virus infection, suggesting increased susceptibility to disease.

18 Nov 2020

Study highlights the disproportionate burden of COVID-19 among Black, Hispanic patients

Research presented today by UT Southwestern cardiologists at the annual American Heart Association (AHA) Scientific Sessions 2020 showed that Black and Hispanic people were more likely to be hospitalized with COVID-19 than white patients, and that nonwhite men with cardiovascular disease or risk factors were more likely to die.

18 Nov 2020

SARS-CoV-2 was circulating in Italy before China recognized its existence

This study, published in the Tumori Journal, sheds light on the possibility that the virus had been spreading in Italy well before the outbreak was officially reported in Wuhan, China.

17 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Effector regulatory T cells (eTreg cells) are a specialized subset of white blood cells that keep the immune system in check.

17 Nov 2020

New AHA COVID-19 CVD Registry details the disparities in care

A new American Heart Association collaborative model for COVID-19 research, using data from the new AHA COVID-19 Cardiovascular Disease Registry, found Hispanic and Black adults with COVID-19 were far more likely to be hospitalized than their white counterparts, as were people with obesity and COVID-19, according to three late-breaking research studies presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Researchers affiliated with the Center for Cell-Based Therapy in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

17 Nov 2020

ECG abnormalities can predict COVID-19 mortality

A team of scientists from New York University Langone Medical Center, USA, has revealed that the clinical severity of hospitalized patients with coronavirus disease 2019 (COVID-19) can be predicted by analyzing the level of troponin elevation and electrocardiographic (ECG) abnormalities. The study is currently available on the medRxiv preprint server.

17 Nov 2020

Novel patient engagement tool improved outcomes for heart failure patients

A novel patient engagement tool led one in five patients with heart failure to a more effective treatment regimen of generic medications, according to late- breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Two-thirds of older Americans would not seek treatment for depression, new poll shows

A new nationwide poll, the GeneSight Mental Health Monitor, shows that nearly two-thirds (61%) of Americans age 65 or older who have concerns about having depression will not seek treatment.

17 Nov 2020

Blood News and Research

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

Severe COVID-19 complications linked to gut barrier breakdown

COVID-19's harmful neurological effects are more common in patients with hypertension, diabetes

Government-funded scientists laid the groundwork for billion-dollar vaccines

Diabetes and hypertension may increase the risk of COVID-19 brain complications

Algorithm-driven program improves cholesterol, blood pressure levels

People with heart disease can receive high-dose or standard-dose flu vaccines for protection

Children in Melbourne family developed COVID-19 immune response after exposure to virus

Noninvasive, self-administered digital tool helps assess risk for preterm delivery

Study: e-cigarette users have increased susceptibility to flu, COVID-19

Study highlights the disproportionate burden of COVID-19 among Black, Hispanic patients

SARS-CoV-2 was circulating in Italy before China recognized its existence

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

New AHA COVID-19 CVD Registry details the disparities in care

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

ECG abnormalities can predict COVID-19 mortality

Novel patient engagement tool improved outcomes for heart failure patients

Two-thirds of older Americans would not seek treatment for depression, new poll shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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