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3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.

9 Nov 2017

Researchers catch killer cells red-handed in the act of microbial murder

Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been able to evade killer cells. This has caused researchers to become interested in finding out the exact mechanism that killer cells use to destroy bacterial invaders.

9 Nov 2017

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

The Center for Applied NanoBioscience and Medicine is doing its part to protect the health of astronauts on long-duration missions, including NASA's Journey to Mars.

9 Nov 2017

Antiviral drug selectively targets the most aggressive viruses, research says

An antiviral drug that inhibits a virus' replication machinery selectively targets the most aggressive viruses, according to new research that looked at the infection of individual cells by a virus and the consequence of antiviral intervention.

9 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Anesthesiologists call for more research into pediatric deaths caused by dental anesthesia

Anesthesiologists call for more research into child deaths caused by dental anesthesia in an article published online by the journal Pediatrics.

9 Nov 2017

Injection of nanoparticles could divert immune cells that cause inflammation

A surprise finding suggests that an injection of nanoparticles may be able to help fight the immune system when it goes haywire, researchers at the University of Michigan have shown. The nanoparticles divert immune cells that cause inflammation away from an injury site.

9 Nov 2017

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside cancer cells in laboratory cultures.

8 Nov 2017

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that's because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death.

8 Nov 2017

Epidural pain relief with fentanyl during childbirth does not affect early breastfeeding success

Including the opioid fentanyl in the solution used to maintain an epidural during childbirth does not appear to affect the success of breastfeeding six weeks after delivery, according to a study published in Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists. Previous research has suggested fentanyl might be associated with early termination of breastfeeding.

8 Nov 2017

Endurance training can be helpful in dealing with muscle inflammation

Endurance training can actually be helpful in dealing with muscle inflammation, according to a new paper co-written by faculty at Binghamton University, State University of New York, and Karolinska Institutet and Karolinska University Hospital in Stockholm, Sweden.

8 Nov 2017

Novel approach could help predict how well patients respond to cancer treatment

A novel approach developed by researchers from the University of Leicester and the MRC Toxicology Unit could help to predict how well patients respond to drugs designed to fight various forms of cancer.

8 Nov 2017

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

DGIST's research team led by Dr. Yun-Il Lee in Well-Aging Research Center has identified a new mechanism of inhibition of dopaminergic neuronal apoptosis and suggested the possibility of preventing and treating Parkinson's disease.

8 Nov 2017

Scientists find way to stimulate growth of new neural connections in the brain

A team led by University of Idaho scientists has found a way to stimulate formation of new neural connections in the adult brain in a study that could eventually help humans fend off memory loss, brain trauma and other ailments in the central nervous system.

8 Nov 2017

New ‘SMART’ system holds potential to accelerate molecular structure identification process

An interdisciplinary team of researchers at the University of California San Diego has developed a method to identify the molecular structures of natural products that is significantly faster and more accurate than existing methods.

8 Nov 2017

Many Americans not aware of major court findings against tobacco companies, survey shows

On Nov. 26, Altria, Philip Morris USA, R.J. Reynolds and other tobacco companies will begin to publish court-ordered "corrective statements" about cigarettes, the result of a 2006 federal court verdict that found the companies in violation of the Racketeer Influenced and Corrupt Organizations Act.

8 Nov 2017

Adipocytes may reduce effectiveness of chemotherapeutic drug

Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.

8 Nov 2017

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.

8 Nov 2017

Major labeling inaccuracies in cannabidiol extract products

There is a growing demand among consumers for marijuana containing products supposedly providing several health benefits in a range od diseases and conditions. This has spawned thousands of websites that are selling these products online. Many of these contain mislabeled cannabidiol (CBD) or a compound found in cannabis or marijuana finds a new study.

7 Nov 2017

Drugs News and Research

3D cultured spheroids could drive precision treatment for ovarian cancer

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

Researchers catch killer cells red-handed in the act of microbial murder

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

Antiviral drug selectively targets the most aggressive viruses, research says

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

Anesthesiologists call for more research into pediatric deaths caused by dental anesthesia

Injection of nanoparticles could divert immune cells that cause inflammation

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Epidural pain relief with fentanyl during childbirth does not affect early breastfeeding success

Endurance training can be helpful in dealing with muscle inflammation

Novel approach could help predict how well patients respond to cancer treatment

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

Scientists find way to stimulate growth of new neural connections in the brain

New ‘SMART’ system holds potential to accelerate molecular structure identification process

Many Americans not aware of major court findings against tobacco companies, survey shows

Adipocytes may reduce effectiveness of chemotherapeutic drug

New discovery in beta-cell pathway shows potential to improve effectiveness of diabetes drugs

Major labeling inaccuracies in cannabidiol extract products

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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