Gliomas News and Research

RSS

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Brain tumors hijack healthy neurons in order to grow

Scientists have discovered that brain tumors integrate themselves with the brain’s healthy neuronal network to support their growth.

19 Sep 2019

A factor that predicts prolonged survival in brain tumor uncovered

The discoveries in the cellular and molecular biology of cancer, the development of drugs against specific genetic mutations, and the emergence of immunotherapy are allowing the cure or improvement of the quality of life and life expectancy of patients with tumors.

3 Sep 2019

Scientists identify unique way to treat incurable type of children's brain cancer

An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute, an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer.

23 Aug 2019

Study calls for more aggressive treatments to improve 5-year survival in glioblastoma patients

Despite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of patients achieving five-year survival remains low, according to new Mayo Clinic research.

23 Jun 2019

Study emphasizes need for more aggressive treatments for glioblastoma patients

20 Jun 2019

Artificial nose helps neurosurgeons to identify cancerous tissue during surgery

An artificial nose developed at Tampere University, Finland, helps neurosurgeons to identify cancerous tissue during surgery and enables the more precise excision of tumors.

17 Jun 2019

Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor Jose Pedro Friedmann Angeli recently published an article in the journal Nature Reviews Cancer, one of the highest-rated journals that occupies the 2nd line in the oncology section among 223 journals in this category and has an impact factor of 42.78 according to WoS data.

7 Jun 2019

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

A recent, updated predictive analysis of the three WHO-defined molecular subgroups based on isocitrate dehydrogenase 1/2 (IDH) mutation status and 1p/19q co-deletion status represented in the high-risk treatment arms of the NRG Oncology clinical trial NRG-RTOG 9802 indicates that both IDH-mutant sub-groups (IDHmut-noncodel and IDHmut-codel) could benefit from the addition of PCV chemotherapy to radiotherapy treatment.

3 Jun 2019

Computer-assisted diagnostic method aids in early detection of brain tumor growth

A computer-assisted diagnostic procedure helps physicians detect the growth of low-grade brain tumors earlier and at smaller volumes than visual comparison alone, according to a study published May 28 in the open-access journal PLOS Medicine by Hassan Fathallah-Shaykh of the University of Alabama at Birmingham, and colleagues.

From PLOS ONE 29 May 2019

Novel imaging technique uses protein found in scorpion venom to light up brain tumors

A novel imaging technique that uses a synthesized form of scorpion venom to light up brain tumors has shown promise in a clinical trial. The imaging system enables neurosurgeons to better see malignant growths that often are difficult to fully eliminate.

10 May 2019

New drug targeting genetic weakness could become first treatment for childhood brain cancer

A new type of drug that targets a genetic weakness in an untreatable childhood brain cancer could become the first ever treatment designed to target the disease.

9 May 2019

Johns Hopkins researchers uncover role of neurotransmitter in the spread of aggressive cancers

Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical "messengers" that transmit impulses from neurons to other target cells.

25 Apr 2019

New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

New combination treatment shows promise for common brain tumor in children

A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models.

22 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Protein content of tumors correlates with treatment response and survival in glioma patients

Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient.

28 Feb 2019

Study suggests new treatment strategy for deadly brain cancer

In a study of mice and human brain tumors researchers at the University of the Michigan, Ann Arbor, searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others.

19 Feb 2019

Early studies and recent clinical trials on nerve growth factor

Nerve growth factor has been playing an important role in development of adult neurobiology. This is because of the regulatory functions that it possesses on survival, growth and differentiation of nerve cells in both of the central and peripheral nervous systems.

21 Jan 2019

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation.

28 Dec 2018