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Study reveals key similarities between the nervous system of two early-diverging animal lineages

Neurons, the specialized cells of the nervous system, are possibly the most complicated cell type ever to have evolved. In humans, these cells are capable of processing and transmitting vast sums of information. But how such complicated cells first came about remains a long-standing debate.

9 Aug 2022

Adults aged ≥50 years boosted with SARS-CoV-2 mRNA vaccines less likely to experience adverse reactions after second booster than during initial booster

A new study monitored the safety of the second booster dose of SARS-CoV-2 messenger ribonucleic acid vaccination among those ≥50 Years.

2 Aug 2022

CDC study describes safety profile of second mRNA COVID booster

The CDC investigates the safety profile of a fourth dose of mRNA-based COVID-19 vaccines in people aged 50 years and older.

1 Aug 2022

Cross-reactive SARS-CoV-2 antibodies after exposure to avian coronavirus vaccine

Researchers identify SARS-CoV-2 cross-reactive antibodies in poultry farm workers exposed to the avian infectious bronchitis virus.

28 Jul 2022

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Researchers discovered a SARS-CoV-2 non-structural protein 2 (NSP2)-mediated mechanism by which it suppresses the production of interferon-beta (IFN-β) in host cells.

27 Jul 2022

The neutralizing antibody response in mRNA vaccinated and boosted healthcare workers against major circulating SARS-CoV-2 Omicron subvariants

Researchers assessed the duration of the neutralizing antibody responses after SARS-CoV-2 mRNA booster vaccination.

27 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

Booster vaccination counters the severity of Omicron breakthrough infections

Researchers assessed a panel of seven SARS-CoV-2 vaccines currently available globally and in the United States and immunity acquired through the previous infection against all Omicron subvariants.

21 Jul 2022

The clinical, epidemiological, and evolutionary consequences of a potential SARS-CoV-2-related bat virus spillover into humans

A team of scientists from France has recently described the epidemiological and clinical consequences of a bat sarbecovirus infection in humanized mice.

20 Jul 2022

COVID-19 vaccine-boosted neutralizing antibody levels decrease substantially within 3 months

Although COVID-19 booster vaccinations in adults elicit high levels of neutralizing antibodies against the Omicron variant of SARS-CoV-2, antibody levels decrease substantially within 3 months, according to new clinical trial data.

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Immunoglobulin G isotypes switch class following repeated SARS-CoV-2 mRNA vaccination

Researchers reported a class switch in SARS-CoV-2-specific antibodies due to repeated mRNA vaccinations.

13 Jul 2022

Immunogenicity and safety of the protein-based heterodimer booster vaccine for COVID-19

Researchers compared the immunogenicity and safety of the protein-based heterodimer vaccine (PHH-1V) and BNT162b2 COVID-19 vaccines.

8 Jul 2022

Broadness of neutralizing antibodies to sarbecoviruses depends on priming conditions

In a recent study under review at the Nature Portfolio journal and currently available on the Research Square* preprint server, researchers identified immune priming conditions that generated broadly neutralizing antibody (nAb) responses and assessed immunity post-third dose of coronavirus disease 2019 (COVID-19) vaccines such as BNT126b2 or Coronavac vaccines after two homologous doses of BNT126b2 or Coronavac vaccines.

7 Jul 2022

COVID-19 and brain damage explained

In a recent study published in the Brain journal, researchers in the United States analyzed the neurovascular injury in coronavirus disease 2019 (COVID-19).

7 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

In a new study,researchers suggested the inclusion of nucleocapsid protein in vaccines against SARS-CoV-2.

5 Jul 2022

Generation of live attenuated influenza A virus vaccine using PROTAC technology

A promising strategy to reduce the impact of viral infectious diseases, such as influenza, is the use of attenuated, live viruses as vaccines.

4 Jul 2022

New, safer CRISPR approach may help correct genetic defects in the future

Curing debilitating genetic diseases is one of the great challenges of modern medicine. During the past decade, development of CRISPR technologies and advancements in genetics research brought new hope for patients and their families, although the safety of these new methods is still of significant concern.

1 Jul 2022

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Researchers explored the molecular basis for increased immunity against heterologous SARS-CoV-2 strains after repeated antigen exposures.