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Study provides new insights into brain signaling during sleep and wakefulness

An international team led by the University of Michigan has introduced new methods that reveal which regions of the brain were active throughout the day with single-cell resolution.

10 Dec 2025

Study reveals how brain protein KCC2 influences reward learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

9 Dec 2025

Laughing gas shows fast antidepressant effects in early clinical trials

A systematic review and meta-analysis in eBioMedicine shows that nitrous oxide can rapidly reduce depressive symptoms within hours, particularly at higher doses, but effects are short-lived after single treatments. Repeated dosing appears to extend and strengthen antidepressant benefits, although the current evidence is based on small, early-phase trials with limited long-term safety data.

8 Dec 2025

Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

An international collaboration led by Cornell University researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain.

5 Dec 2025

Researchers highlight five pathways through which microplastics can harm the brain

Microplastics could be fueling neurodegenerative diseases like Alzheimer's and Parkinson's, with a new study highlighting five ways microplastics can trigger inflammation and damage in the brain.

5 Dec 2025

Study shows glial cells actively shape addictive responses to nicotine

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult.

4 Dec 2025

Scientists reveal new mechanisms of electrical oscillations in neurons

Researchers at UT San Antonio have uncovered new details about electrical signals happening within nerve cells, deepening scientists' understanding of the brain.

3 Dec 2025

Hidden cellular layers in the hippocampus' CA1 region revealed

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have identified a previously unknown pattern of organization in one of the brain's most important areas for learning and memory.

3 Dec 2025

Global analysis shows rising burden of ALS and motor neuron diseases

Amyotrophic lateral sclerosis (ALS) and other motor neuron diseases (MNDs) are major global causes of death. However, their global incidence, mortality, and disability-adjusted life years remain largely unknown, despite their importance for disease prevention and resource allocation.

27 Nov 2025

New imaging protocol captures mouse brain cell connections in precise detail

An international team of researchers led by the Francis Crick Institute, working with the Paul Scherrer Institute, have developed a new imaging protocol to capture mouse brain cell connections in precise detail.

27 Nov 2025

New imaging method reveals nanodomains inside ALS-linked protein droplets

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

26 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Prefrontal cortex modulates visual and motor regions based on internal feelings

Vision shapes behavior and, a new study by MIT neuroscientists finds, behavior and internal states shape vision.

25 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Computational modeling helps simulate key stages of retinogenesis

New computer modeling could help scientists better understand how the retina regenerates, opening the door to new treatments for vision loss, according to a study from the University of Surrey.

25 Nov 2025

Researchers use organoids to study the earliest moments of electrical activity in the brain

Humans have long wondered when and how we begin to form thoughts. Are we born with a pre-configured brain, or do thought patterns only begin to emerge in response to our sensory experiences of the world around us? Now, science is getting closer to answering the questions philosophers have pondered for centuries.

24 Nov 2025