Septic Shock News and Research

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Updated SSC Bundle aims to improve survival for sepsis patients

For patients with sepsis, a serious infection causing widespread inflammation, immediate treatment is essential to improve the chances of survival. An updated "Hour-1 Bundle" of the international, evidence-based guidelines for treatment of sepsis is introduced in the June issue of Critical Care Medicine.

18 May 2018

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

An international research team led by the Institute of Bioengineering and Nanotechnology of the Agency for Science, Technology and Research and IBM Research developed a synthetic molecule that can kill five deadly types of multidrug-resistant bacteria with limited, if any, side effects.

7 Mar 2018

Platelets play more important role in the immune system than previously thought

Platelets play a much more important role in our immune system than previously thought, according to a study published by researchers from Université Laval and Centre hospitalier universitaire de Québec Research Center.

1 Feb 2018

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Disorders caused by a leaky vasculature are more common than most people think. Despite ICU treatment, one third of the 27 million patients globally that suffer from sepsis, and up to 20% of the more than 5 million US patients with congestive heart failure die every year from their condition.

5 Jan 2018

Macrophage nanosponges offer promising solution for effectively managing sepsis

A team of researchers at the University of California San Diego has developed macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis.

4 Jan 2018

Review calls for improvement in post-hospital recovery care for sepsis survivors

Despite improvement in the rates of people dying of sepsis in the hospital, the condition is still a leading cause of hospital readmissions and costs, as well as long-term disabilities and impairments, prompting University of Pittsburgh and University of Michigan medical scientists to develop thorough recommendations for post-hospital recovery care and future clinical trials.

2 Jan 2018

Multiple sclerosis drug can beat obstinate bacteria

Encountering bacteria with innocent names such as Pseudomonas aeruginosa and Enterobacteriaceae can lead to hospitalization and - in a worst-case scenario - can also be life-threatening. The bacteria, which cause infections such as pneumonia, frequently develop multi-resistance towards classic antibiotics.

22 Nov 2017

Electronic alert system helps clinicians to quickly identify children with severe sepsis in ER

An electronic alert system helps clinicians quickly do a bedside assessment to identify children with severe sepsis in an emergency department. Researchers from Children's Hospital of Philadelphia report on their efforts to rapidly recognize this life-threatening condition.

13 Sep 2017

Differentiating sepsis and systemic inflammatory response syndrome using biomarkers

Firstly, it is necessary to make a distinction between systemic inflammation and Systemic Inflammatory Response Syndrome (SIRS). SIRS consists of changes in clinical signs including an abnormal body temperature, increased heart rate, increased respiratory rate, an abnormal white cell count (either decreased or elevated), or an increase in band neutrophils.

7 Sep 2017

Intensive Care Medicine

Intensive care medicine is a young specialty that deals with the medical treatment of the sickest patients in the hospital. Intensive care medicine doctors are called intensivists and are expert physicians with special skills in the management of organ failure.

29 Aug 2017

Research shows probiotics can reduce incidence of sepsis in infants

A research team at the University of Nebraska Medical Center College of Public Health has determined that a special mixture of good bacteria in the body reduced the incidence of sepsis in infants in India by 40 percent at a cost of only $1 per infant.

16 Aug 2017

Opioid crisis results in increased admissions to hospital ICUs and deaths

The opioid crisis in the United States is resulting in increased admissions to hospital intensive care units and in increased numbers of ICU deaths from opioid overdoses, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

11 Aug 2017

New diagnostic system enables rapid, accurate customization of antibiotic treatments

A diagnostic system developed at the Technion-Israel Institute of Technology enables rapid and accurate customization of the antibiotic to the patient.

29 Jun 2017

Drug cocktail may be effective in preventing progressive organ dysfunction, deaths from sepsis

Sepsis presents a major challenge for health care providers, especially in low-income countries where the mortality rate can exceed 60 percent.

27 Jun 2017

Antibiotic resistance: a healthcare emergency?

Antibiotic resistance is happening in hospitals quite frequently. Probably the main place where resistant organisms and pathogens are acquired is in intensive care units (ICUs).

26 Jun 2017

The new war on sepsis

Dawn Nagel, a nurse at St. Joseph Hospital in Orange, Calif., knew she was going to have a busy day, with more than a dozen patients showing signs of sepsis.

21 Jun 2017

New tool to identify children with severe sepsis reduces missed diagnoses by 76%

An electronic sepsis alert using a combination of vital signs, risk factors and physician judgment to identify children in a pediatric emergency department with severe sepsis reduced missed diagnoses by 76 percent.

7 Jun 2017

New study suggests potential new therapeutic approach to septic shock recovery

A new study published online in the Journal of Leukocyte Biology suggests a new approach to treating patients with sepsis, one of the most frequent causes of morbidity and mortality in intensive care units.

1 Jun 2017

Machine-learning algorithm may help identify hospitalized patients at risk for severe sepsis

A machine-learning algorithm has the capability to identify hospitalized patients at risk for severe sepsis and septic shock using data from electronic health records, according to a study presented at the 2017 American Thoracic Society International Conference.

24 May 2017

Overcrowded emergency rooms may delay sepsis treatment, study reveals

According to a new study, patients with sepsis, a life-threatening complication of an infection, had delays approaching one hour in being given antibiotics when seen in emergency rooms that were overcrowded. The study was presented at the 2017 American Thoracic Society International Conference.

22 May 2017