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Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

Researchers evaluate the response of pre-existing immunity to booster doses of mRNA COVID-19 vaccines.

6 Mar 2023

IgG4 serum levels do not show elevation in post-COVID syndrome

In a recent study posted to bioRxiv* preprint server, researchers in Germany assessed the differences in antigen-specific immunoglobulin G (IgG) subtypes between post-COVID syndrome (PCS) patients and convalescent controls.

6 Mar 2023

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

In a recent study posted to the bioRxiv* preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

3 Mar 2023

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Nanomaterials inspired by amyloid proteins are gaining interest in nanotechnology, due to their modularity, controlled self-assembly and stability.

28 Feb 2023

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can only receive supportive care while they wait for their own body to clear the infection.

24 Feb 2023

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

Researchers assessed the impact of COVID-19 on fibrotic pathogenesis via the deregulation of mitochondrial beta-oxidation.

23 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Omicron has higher risk of in-hospital mortality compared to influenza

In a recent study published in the journal JAMA Network Open, researchers compared the hospital outcomes of patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with those of influenza patients in Switzerland, assess the current disease burden due to coronavirus disease 2019 (COVID-19).

16 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

New insights into the role of T-cells during long COVID

Researchers characterize the trajectory of long COVID in patients eight months after recovering from infection.

14 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Researchers assess the impact of COVID-19 vaccination on immune responses during a breakthrough infection.

9 Feb 2023

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Heterologous vaccination improves the neutralization of SARS-CoV-2 Omicron sub-variants.

9 Feb 2023

Assessing the zoonotic potential of different coronaviruses in hedgehogs, moles and shrews

Researchers examine the phylogenetic relationships between Eulipotyphla coronaviruses and related coronaviruses.

9 Feb 2023

Antibodies against SARS-CoV-2 are higher in infants than in mothers

Researchers characterize the functional and binding antibody responses against SARS-CoV-2 in postpartum women and their infected infants.

9 Feb 2023

Researchers discover small molecules that can lock SARS-CoV-2 spike proteins

The infamous spike proteins on the surface of SARS-CoV-2 help it bind to and enter human cells. Because of their important role in spreading infection, these spike proteins are one of the main targets for COVID-19 vaccines and treatments.

9 Feb 2023

Spike Protein News and Research

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

Antibody levels from prime COVID-19 mRNA vaccine influences the efficacy of booster doses

IgG4 serum levels do not show elevation in post-COVID syndrome

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

Researchers develop protein-based nanoparticles to neutralize SARS-CoV2 virus

Study analyzes the potential of a natural amino acid as new way to cure COVID-19

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Omicron has higher risk of in-hospital mortality compared to influenza

Smoking and vaping may put healthy young people at risk of severe COVID

Delayed presentation of MIS-C following COVID-19

New insights into the role of T-cells during long COVID

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Heterologous inactivated virus/mRNA booster strongly augments response to BF.7, BQ.1.1, and XBB.1

Assessing the zoonotic potential of different coronaviruses in hedgehogs, moles and shrews

Antibodies against SARS-CoV-2 are higher in infants than in mothers

Researchers discover small molecules that can lock SARS-CoV-2 spike proteins

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