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Bright-light therapy may reduce attention lapses during night work

Light therapy may improve alertness and attention/reaction time during simulated night shifts, with the strongest benefits appearing after light exposure. Effects on executive function were smaller and largely limited to treatment, while substantial study heterogeneity and limited real-world evidence warrant caution.

11 Aug 2026

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

11 Aug 2026

Traditional prostate cancer features fail to predict hormone therapy benefit

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while traditional pathological features used to classify aggressive prostate cancer -such as high-grade disease, cancer extending outside the prostate and cancer involving the seminal vesicles- after surgery can help identify patients who are more likely to have worse outcomes, they do not predict who will benefit more from adding hormone therapy to postoperative radiation.

10 Aug 2026

New gene signature predicts immunotherapy success for bone marrow cancers

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026

Optimal prostate-specific antigen cutoff linked to improved prostate cancer survival

After treatment for metastatic prostate cancer, a drop in prostate-specific antigen (PSA) levels in the blood is an indicator that the treatment is working.

10 Aug 2026

Spatial transcriptomics study elucidates cellular dynamics during heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

10 Aug 2026

New combination therapy could permanently clear HIV in newborns

Every year, more than 120,000 newborns worldwide contract HIV, a global health burden that requires lifelong treatment for millions of people - assuming they have access and can afford it.

10 Aug 2026

Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

A single 25-mg dose of psilocybin with psychological support was feasible to deliver within an NHS setting and produced large preliminary reductions in depressive symptoms among adults with treatment-resistant depression. The Phase 2 feasibility trial also found the treatment was generally well tolerated, although functional unblinding and expectancy effects mean larger, longer efficacy studies are needed.

10 Aug 2026

New drug delivers promising survival gains in pancreatic cancer

About 90% of people with pancreatic cancer have pancreatic ductal adenocarcinoma (PDAC), which is driven by an activating mutation in the KRAS gene.

9 Aug 2026

Two-gene interaction reveals metastatic risk in breast cancer

Why do some breast cancer patients face a much higher risk of distant metastasis, while others with seemingly similar disease experience far better outcomes?

7 Aug 2026

Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma

The aberrant activation of the mTOR pathway and its crosstalk with other signaling cascades represent key drivers of hepatocellular carcinoma (HCC) progression. mTOR-mediated ferroptosis suppression has been implicated in HCC resistance to chemotherapy.

7 Aug 2026

Growth hormone therapy improves height after childhood stem cell transplants

Growth impairment is a common late effect of childhood stem cell transplantation. A Japan-wide study found that growth hormone therapy improves adult height, but prior radiation therapy and transplant-related complications negatively affect how much children benefit.

7 Aug 2026

Researchers find a new genetic vulnerability in acute myeloid leukemia

A study published in Nature Cell Biology reports a new vulnerability in acute myeloid leukemia (AML) that might lead to novel therapies to treat this cancer while minimizing harm to normal cells.

7 Aug 2026

Piezo ion channels: Key regulators of digestive health and disease

Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.

7 Aug 2026

Scientists map key differences in stem cell potency for treating knee osteoarthritis

Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life.

7 Aug 2026

Nicotine gum may make smokeless tobacco withdrawal easier to manage

A randomized trial found that 2 mg nicotine gum controlled craving, anxiety, and sleep problems more effectively than behavioral counselling during smokeless tobacco cessation. Although abstinence rates were numerically higher with nicotine gum, the differences were not statistically significant, highlighting the need for larger studies.

6 Aug 2026

D-serine promotes gastric cancer growth by suppressing tumor immunity

Researchers from Keio University have found that D-serine increases the growth of gastric cancer by creating an immunosuppressive and anti-inflammatory tumor microenvironment.

6 Aug 2026

Early radionuclide therapy delays progression in metastatic prostate cancer

Earlier use of a targeted radionuclide therapy delays metastatic prostate cancer progression when administered as part of a trio of drugs, according to a phase 3 clinical trial led by Weill Cornell Medicine, NewYork-Presbyterian, Memorial Sloan Kettering Cancer Center and investigators at several other institutions worldwide.

6 Aug 2026

Omega-3 and ASA combination shows promise for severe periodontitis

A combination of omega-3 and low-dose acetylsalicylic acid (ASA) produced results comparable to antibiotics in treating severe periodontitis.

6 Aug 2026

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

A growing body of evidence suggests that a rare epithelial cell type known as the tuft cell may play a far more significant role in cancer than previously recognized.

6 Aug 2026

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Therapy News and Research

Bright-light therapy may reduce attention lapses during night work

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

Traditional prostate cancer features fail to predict hormone therapy benefit

New gene signature predicts immunotherapy success for bone marrow cancers

Optimal prostate-specific antigen cutoff linked to improved prostate cancer survival

Spatial transcriptomics study elucidates cellular dynamics during heart transplant rejection

New combination therapy could permanently clear HIV in newborns

Single-dose psilocybin shows promise for treatment-resistant depression in NHS trial

New drug delivers promising survival gains in pancreatic cancer

Two-gene interaction reveals metastatic risk in breast cancer

Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma

Growth hormone therapy improves height after childhood stem cell transplants

Researchers find a new genetic vulnerability in acute myeloid leukemia

Piezo ion channels: Key regulators of digestive health and disease

Scientists map key differences in stem cell potency for treating knee osteoarthritis

Nicotine gum may make smokeless tobacco withdrawal easier to manage

D-serine promotes gastric cancer growth by suppressing tumor immunity

Early radionuclide therapy delays progression in metastatic prostate cancer

Omega-3 and ASA combination shows promise for severe periodontitis

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

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