Therapy News and Research

RSS

Amphista Therapeutics announces first patient dosed in AMX-883 Phase 1 clinical trial for acute myeloid leukemia

Amphista Therapeutics Limited ('Amphista'), a leader in the discovery and development of non-cereblon / VHL targeted protein degradation (TPD) medicines, today announced dosing of the first patient in a Phase 1 trial for its lead candidate, AMX-883. Initiated following authorization from the U.S. Food and Drug Administration in June 2026, the BRAMLIE trial will investigate the safety, pharmacokinetics, and preliminary efficacy of AMX-883 monotherapy in participants with AML and high-risk MDS.

From Amphista Therapeutics 12 Oct 2026

Study reveals continued care delays among patients with young-onset breast cancer

In an analysis of data on adolescents and young adults with breast cancer, lower income and younger age were linked with delays in care.

12 Oct 2026

Adding a chatbot to specialist care helped young people make sense of cancer risk

In a randomized trial of 106 adolescents and young adults with hereditary cancer predisposition, adding AYA-RISE to a clinic visit improved knowledge of cancer risk before age 30 compared with a clinic visit alone. Researchers observed no increase in distress, but the main analyses did not establish additional benefits for lifetime-risk or screening knowledge.

12 Oct 2026

Better blood pressure control could prevent over 518,000 annual deaths worldwide

Effective management of high blood pressure could prevent more than 518,000 annual deaths from cardiovascular disease around the world, according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2026.

11 Oct 2026

Stopping GLP-1 drugs often brings weight back. A small trial suggests ways to slow it

In a randomized pilot trial of 39 adults, researchers found that participants receiving medically tailored meals or Noom regained about 3.6% of their body weight over four months after stopping GLP-1 therapy, compared with about 11% under usual care. These exploratory findings suggest structured support may slow early weight regain, but the small sample and short follow-up leave lasting benefits uncertain.

11 Oct 2026

A trial of 3,220 smokers puts cash rewards for quitting to the test

In a randomized trial of 3,220 medically underserved adults referred for lung cancer screening, adding financial incentives to usual care and free medication increased sustained smoking abstinence at six months. Offering free medication alone did not significantly increase quit rates, and adding a forward-looking mobile tool did not improve outcomes beyond the incentives.

11 Oct 2026

New project aims to test a protein-based therapy for Fragile X syndrome

A new research project at the University of California, Riverside, has received funding to investigate whether a novel protein-based therapy can correct abnormal brain activity associated with Fragile X syndrome.

9 Oct 2026

Friends of BrainHealth grants advance dementia prevention and brain health research

For nearly 20 years, the Friends of BrainHealth donor circle has helped turn promising ideas into innovative brain health research.

9 Oct 2026

Nasal immune adjuvant protects mice against respiratory viruses for months

The COVID-19 pandemic showed the challenges of protecting populations when a new respiratory virus emerges.

9 Oct 2026

Molecular regulator CA8 may offer new therapeutic target for type 2 diabetes

Maintaining healthy blood glucose levels involves striking a balance between the glucose produced by the liver during fasting, and the insulin released from pancreatic beta cells after meals.

9 Oct 2026

New signaling pathway enhances blood stem cell transplantation outcomes

Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve their full potential after transplantation.

9 Oct 2026

Sutter Health care model safely expands local Alzheimer's treatment

A multidisciplinary care model developed across Sutter Health helped general neurologists address a practical challenge facing health systems nationwide: how to safely offer newer Alzheimer's disease treatments in community settings to more patients.

9 Oct 2026

Polymeric nanomedicine strategies improve solid tumor immunotherapy outcomes

Solid tumors are not merely collections of malignant cells but complex ecosystems comprising tumor cells, stromal cells, and the extracellular matrix (ECM).

9 Oct 2026

FDA approves atezolizumab combination for stage III colon cancer with deficient DNA mismatch repair

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has approved the immunotherapy drug atezolizumab (Tecentriq) in combination with fluoropyrimidine and oxaliplatin chemotherapy, for the adjuvant treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

9 Oct 2026

Study explains why cancer immunity declines faster in males

Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and Tim Padera, PhD, currently of the Mass General Brigham Cancer Institute, are the lead and senior authors of a paper published in Nature Aging, "Lymph node contraction links sex-biased naive CD8 T cell decline to compromised antigen recognition during middle age."

9 Oct 2026

Oncopeptides confirms blood-brain-barrier penetration based on data from first patients in glioblastoma Window-of-Opportunity (WoO) study

Oncopeptides AB (publ), a biotech company specializing in difficult-to-treat cancers, today announces data from the first patients in its ongoing clinical Window-of-Opportunity (WoO) study, OP-701 (INSULA), evaluating its proprietary Peptide Drug Conjugate (PDC) platform in glioblastoma.

9 Oct 2026

Gut bacteria may help explain why endometriosis pain varies

A study of 50 women with surgically confirmed endometriosis found that differences in gut bacterial composition were associated with menstrual pain, urinary symptoms, and infertility.

9 Oct 2026

$13.1 million grant backs bacterial therapies for resistant breast cancer

A scientist at Weill Cornell Medicine is working with colleagues at the University of Massachusetts Amherst on new, complementary research efforts engineering therapeutic Salmonella to target critical gaps in treatment for drug-resistant triple-negative breast cancers.

9 Oct 2026

Precise phenotyping improves genetic prediction of sensorineural hearing loss

A team of hearing specialists at Vanderbilt Health analyzed thousands of data samples in the institution’s BioVU biobank to understand genetic susceptibility of sensorineural hearing loss, which is caused by damage to the inner ear.

8 Oct 2026

New long-acting HIV treatment offers hope for drug-resistant infections

A new long-acting HIV treatment could expand options for people who have trouble taking daily pills and whose virus is resistant to some commonly used HIV drugs, according to a new UC San Francisco study.

8 Oct 2026

Previous
1
...
8
9
10
11
12
13
14
...
2953
Next

Therapy News and Research

Amphista Therapeutics announces first patient dosed in AMX-883 Phase 1 clinical trial for acute myeloid leukemia

Study reveals continued care delays among patients with young-onset breast cancer

Adding a chatbot to specialist care helped young people make sense of cancer risk

Better blood pressure control could prevent over 518,000 annual deaths worldwide

Stopping GLP-1 drugs often brings weight back. A small trial suggests ways to slow it

A trial of 3,220 smokers puts cash rewards for quitting to the test

New project aims to test a protein-based therapy for Fragile X syndrome

Friends of BrainHealth grants advance dementia prevention and brain health research

Nasal immune adjuvant protects mice against respiratory viruses for months

Molecular regulator CA8 may offer new therapeutic target for type 2 diabetes

New signaling pathway enhances blood stem cell transplantation outcomes

Sutter Health care model safely expands local Alzheimer's treatment

Polymeric nanomedicine strategies improve solid tumor immunotherapy outcomes

FDA approves atezolizumab combination for stage III colon cancer with deficient DNA mismatch repair

Study explains why cancer immunity declines faster in males

Oncopeptides confirms blood-brain-barrier penetration based on data from first patients in glioblastoma Window-of-Opportunity (WoO) study

Gut bacteria may help explain why endometriosis pain varies

$13.1 million grant backs bacterial therapies for resistant breast cancer

Precise phenotyping improves genetic prediction of sensorineural hearing loss

New long-acting HIV treatment offers hope for drug-resistant infections

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News