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Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

A three-drug combination that sent chronic lymphocytic leukemia (CLL) into deep remissions in a broad group of patients in a clinical trial is highly effective in patients with high-risk forms of the disease, a new, phase 2 clinical trial led by Dana-Farber Cancer Institute investigators indicates.

12 Dec 2022

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

12 Dec 2022

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

Strontium-loaded hydrogel scaffolds promote wound healing by stimulating gingival fibroblast activity

A team of University at Buffalo researchers has developed a new strontium-loaded scaffold that can be personalized to fit any size dental implant and could help improve healing and tissue attachment in patients.

9 Dec 2022

Researchers discover a previously unknown mechanism that drives aging

Northwestern University researchers have discovered a previously unknown mechanism that drives aging.

9 Dec 2022

What is the importance of vitamin B12 supplementation in plant-based diets?

Researchers emphasize the importance of vitamin B12 supplementation for individuals consuming a plant-based or vegan diet.

9 Dec 2022

For patients with sickle cell disease, fertility care is about reproductive justice

Teonna Woolford has always wanted six kids. Why six? "I don't know where that number came from. I just felt like four wasn't enough," said Woolford, a Baltimore resident. "Six is a good number."

8 Dec 2022

Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

University of Central Florida researchers have created unique technology for treating osteoporosis that uses nanobubbles to deliver treatment to targeted areas of a person's body.

6 Dec 2022

The critical role of flow cytometry in CAR+ T-Cell trials

In this interview, Ryan Muise talks to AZoNetwork about the added value of using flow cytometry in CAR T-Cell clinical trials.

From Cerba Research 6 Dec 2022

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

The Ajmera Transplant Centre at University Health Network (UHN) has performed a groundbreaking parathyroid transplant, in a patient who suffered from a severe form of hypoparathyroidism – when there is little or no parathyroid function.

5 Dec 2022

NYU Langone’s Center for Amputation Reconstruction now adds osseointegration treatment to its other surgical techniques

NYU Langone Health has completed its first set of surgeries using the only U.S. Food and Drug Administration (FDA)-approved implantable prosthetic for people with limb loss available in the greater New York City area.

1 Dec 2022

HU begins human trial for promising treatment to reverse paralysis and language disorder after stroke

Hiroshima University started the human trial for a promising treatment that offers hope in potentially reversing paralysis and language disorder after moderate to severe stroke using therapeutically superior mesenchymal stem cells (MSCs) derived from the cranial bone.

1 Dec 2022

Scientists discover new potential mechanism for vision loss

Visual cells in the human retina may not simply die in some diseases, but are mechanically transported out of the retina beforehand.

1 Dec 2022

Study suggests new strategies for making cartilage cells

As any weekend warrior understands, cartilage injuries to joints such as knees, shoulders, and hips can prove extremely painful and debilitating. In addition, conditions that cause cartilage degeneration, like arthritis and temporomandibular joint disorder (TMJ), affect 350 million people in the world and cost the US public health system more than $303 billion every year.

30 Nov 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Mediterranean diet provides many benefits to overweight and obese seniors

The World Health Organization (WHO) defines overweight and obesity as excessive fat accumulations, posing health risks. A Spanish survey indicated a significant increase in obesity (from 7.4 % to 17.4%.) between 1987 and 2017. Interestingly, it was observed that obesity is more prevalent in men than in women who are below 65 years of age. However, beyond the age of 65, obesity in women outnumbered men.

29 Nov 2022

Corticosteroid injections associated with progression of knee osteoarthritis

Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease.

29 Nov 2022

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Researchers used ribonucleic acid (RNA) sequence data to understand the association between inflammatory cytokines and poor outcomes of pediatric Acute Myeloid Leukemia (pAML).

29 Nov 2022

Bone News and Research

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Strontium-loaded hydrogel scaffolds promote wound healing by stimulating gingival fibroblast activity

Researchers discover a previously unknown mechanism that drives aging

What is the importance of vitamin B12 supplementation in plant-based diets?

For patients with sickle cell disease, fertility care is about reproductive justice

Low-intensity ultrasound therapies may help rebuild stronger knees

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

The critical role of flow cytometry in CAR+ T-Cell trials

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

NYU Langone’s Center for Amputation Reconstruction now adds osseointegration treatment to its other surgical techniques

HU begins human trial for promising treatment to reverse paralysis and language disorder after stroke

Scientists discover new potential mechanism for vision loss

Study suggests new strategies for making cartilage cells

The effects of mechanical forces on musculoskeletal cells and tissues

Mediterranean diet provides many benefits to overweight and obese seniors

Corticosteroid injections associated with progression of knee osteoarthritis

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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