Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich has now discovered that microRNA 29 (miR-29) plays an important role in the formation of tissue fibrosis.

23 Nov 2017

Multiple sclerosis drug can beat obstinate bacteria

Encountering bacteria with innocent names such as Pseudomonas aeruginosa and Enterobacteriaceae can lead to hospitalization and - in a worst-case scenario - can also be life-threatening. The bacteria, which cause infections such as pneumonia, frequently develop multi-resistance towards classic antibiotics.

22 Nov 2017

CF patients in the U.S. show faster rate of improvement in lung function and nutrition

New research comparing cystic fibrosis patients in the United States and Canada showed that, although the patients' nutritional status and lung function improved in both countries over the period from 1990 to 2013, the rate of improvement was faster in the United States.

22 Nov 2017

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Columbia University biologists have revealed a mechanism by which bacterial cells in crowded, oxygen-deprived environments access oxygen for energy production, ensuring survival of the cell. The finding could explain how some bacteria, such as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive in oxygen-poor environments like biofilms and resist antibiotics.

21 Nov 2017

Simple test could help predict best treatment for cystic fibrosis patients

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs are life-changing for some patients, they do not work for everyone.

21 Nov 2017

Pioneering research project aims to develop better diagnostic tests for NAFLD

A pioneering European research project aims to lead to new diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD) and identify those most at risk for developing severe inflammation and liver scarring.

21 Nov 2017

Cystic fibrosis patients have more good and bad bacteria in their lungs, study finds

A large multicenter study found that patients with cystic fibrosis (CF) – who tend to develop chronic lung infections – had more good and bad bacteria in their lungs compared to controls.

20 Nov 2017

All mouth cancer patients in Myanmar use smokeless tobacco, study finds

A study in Myanmar has found that all mouth cancer patients use smokeless tobacco, researchers report at the ESMO Asia 2017 Congress. Betel quid chewing often starts in adolescence and is associated with smoking and drinking alcohol, which are also risk factors for oral cancer.

20 Nov 2017

New model to test effectiveness of existing and potential CF therapies

UNC School of Medicine researchers have developed a new laboratory model of the infection- and inflammation-plagued airways of cystic fibrosis (CF) patients.

17 Nov 2017

New discovery about immune system could pave way for better allergy treatment

Scientists have made a fundamental discovery about how our body's immune system clears harmful infections.

16 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

A team of Massachusetts General Hospital researchers has developed a potential alternative to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging.

15 Nov 2017

SUNY Downstate professor receives two awards to support research on vision-threatening diseases

Brahim Chaqour, PhD, professor of cell biology and ophthalmology at SUNY Downstate Medical Center, has received two awards to support research into treatment of currently incurable vision-threatening diseases. The new awards, totaling $2,008,973, are from the National Eye Institute of the National Institutes of Health.

14 Nov 2017

Using AFM to study cancer cells

An interview with Prof. Hermann Schillers, Universität Münster conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 14 Nov 2017

Experts drive Neem Biotech’s efforts to counter effects of antimicrobial resistance on treatment of lung infections

Neem Biotech, the Welsh-based fundamental Research and Development arm of the Zaluvida group of life science companies, is pleased to present an interview with two thought leaders in the field of bacterially-caused chronic lung infections.

From Neem Biotech 9 Nov 2017

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that's because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death.

8 Nov 2017

Fat hormone associated with NASH may be effective target for therapeutic intervention

The rising obesity epidemic has brought with it an army of maladies. One, in particular, is threatening to outpace many of the disorders that accompany obesity, in terms of occurrence and severity: nonalcoholic fatty liver disease.

7 Nov 2017

Quorum sensing data presented at the North American Cystic Fibrosis Conference by Neem Biotech

Neem Biotech, the Welsh-based fundamental Research and Development arm of the Zaluvida group of life science companies, was pleased to present the work into development of a novel mode of action as an adjunct to existing antibiotics at the North American Cystic Fibrosis Conference Indiana, USA from 2nd November 2017 to 4th of November 2017.

From Neem Biotech 6 Nov 2017

Sickle cell patients suffer discrimination, poor care — and shorter lives

For more than a year, NeDina Brocks-Capla avoided one room in her large, brightly colored San Francisco house — the bathroom on the second floor.

6 Nov 2017

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

From Neem Biotech 3 Nov 2017

Fibrosis News and Research

Further Reading

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Multiple sclerosis drug can beat obstinate bacteria

CF patients in the U.S. show faster rate of improvement in lung function and nutrition

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Simple test could help predict best treatment for cystic fibrosis patients

Pioneering research project aims to develop better diagnostic tests for NAFLD

Cystic fibrosis patients have more good and bad bacteria in their lungs, study finds

All mouth cancer patients in Myanmar use smokeless tobacco, study finds

New model to test effectiveness of existing and potential CF therapies

New discovery about immune system could pave way for better allergy treatment

Study identifies molecular pathway critical to development of fibrosis

MGH researchers develop potential alternative to gadolinium-based MRI contrast agents

SUNY Downstate professor receives two awards to support research on vision-threatening diseases

Using AFM to study cancer cells

Experts drive Neem Biotech’s efforts to counter effects of antimicrobial resistance on treatment of lung infections

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Fat hormone associated with NASH may be effective target for therapeutic intervention

Quorum sensing data presented at the North American Cystic Fibrosis Conference by Neem Biotech

Sickle cell patients suffer discrimination, poor care — and shorter lives

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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