Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

Regular surveillance testing of a community can prevent Covid-19 outbreaks

Covid-19 is often asymptomatic and can lead infected individuals to spread the disease without knowing it. Yet, regular surveillance testing of a community can catch these cases and prevent outbreaks.

10 Feb 2022

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.

9 Feb 2022

Super-resolution imaging of the human coronavirus genome during infection

Using high-throughput confocal super-resolution microscopy, scientists visualize the genomic material of the human coronavirus HCoV-229E.

9 Feb 2022

Prevalence of genetic susceptibility to cardiac arrhythmia may be underestimated, study says

By sequencing known genes associated with cardiac arrhythmia risk in more than 20,000 people without an indication for genetic testing, scientists were able to identify pathogenic and likely pathogenic variants in nearly one percent of individuals, according to a study published in Circulation.

9 Feb 2022

Innate immune specificity is driven by the nervous system, study suggests

Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with can respond differently to specific pathogens.

9 Feb 2022

SPT Labtech paves the way for a new era of genomics liquid handling with firefly® launch

SPT Labtech today announced the launch of firefly®, an innovative liquid handling platform for next-generation sequencing (NGS) library preparation.

From SPT Labtech 9 Feb 2022

Northwestern researchers study COVID-19 mechanisms, infection patterns and impact on gender minorities

Northwestern Medicine investigators continue to study the COVID-19 pandemic, from the biological mechanisms of disease and infection patterns to the pandemic's impact on women and sexual and gender minorities.

6 Feb 2022

Global efforts to track COVID-19 variants grossly underreported a probable variant of concern in Nigeria

If the United States ignores COVID-19 in Nigeria, we forgo global genomic surveillance at our own peril, reports a new Northwestern Medicine study published in Nature Communications.

3 Feb 2022

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

A genetic variant changing just one base pair of nucleotides greatly increases risk of a high-risk subtype of childhood acute lymphoblastic leukemia (ALL), according to a Northwestern Medicine study published in Nature Genetics.

3 Feb 2022

New method may be effective at quantifying DNA adenine methylation in complex organisms

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

3 Feb 2022

CRISPRa method helps discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

3 Feb 2022

Researchers receive $2,664,522 NIH award to improve long-term functionality of vascular grafts

A graft can be a life-saving device for coronary heart disease, which remains the leading cause of death for both men and women in the United States. However, at small diameters - such as the coronary artery in the heart - long-term graft failure rates are often higher than 40 percent.

2 Feb 2022

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

A new study by researchers at Yale Cancer Center shows inhibition of the CECR2 gene prevents triple-negative breast cancer from advancing or metastasizing.

2 Feb 2022

'Genetic scissors' can give rise to unforeseen heritable mutations

CRISPR-Cas9, the "genetic scissors", creates new potential for curing diseases; but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that can be inherited by the next generation.

2 Feb 2022

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions in the gut microbiome - the bacteria and other microbes that live inside us - but no existing treatments actually target these microorganisms.

2 Feb 2022

Researchers discover why patients suffering with hypertension also have diabetes

The long-standing enigma of why so many patients suffering with high blood pressure (known as hypertension) also have diabetes (high blood sugar) has finally been cracked by an international team led by the universities of Bristol, UK, and Auckland, New Zealand.

1 Feb 2022

C-Path and EJP RD collaborate to expand global rare disease research and drug development

Critical Path Institute (C-Path), an independent global nonprofit organization, and the European Joint Programme on Rare Diseases (EJP RD), an initiative that has received funding from the European Union's Horizon 2020 research and innovation programme, have announced a collaboration to advance technologies and methodologies that are fit for regulatory purposes to further global rare disease research and drug development.

1 Feb 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

ERGA aims to provide genomic data to inform research about Europe's biodiversity

To provide important genomic data to inform research about Europe's biodiversity, scientists from 48 different countries initiated the "European Reference Genome Atlas" (ERGA) in 2021.

28 Jan 2022

Genomics News and Research

Further Reading

First unbiased proteome scale study expands the number of known transcriptional activators

Regular surveillance testing of a community can prevent Covid-19 outbreaks

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Super-resolution imaging of the human coronavirus genome during infection

Prevalence of genetic susceptibility to cardiac arrhythmia may be underestimated, study says

Innate immune specificity is driven by the nervous system, study suggests

SPT Labtech paves the way for a new era of genomics liquid handling with firefly® launch

Northwestern researchers study COVID-19 mechanisms, infection patterns and impact on gender minorities

Global efforts to track COVID-19 variants grossly underreported a probable variant of concern in Nigeria

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

New method may be effective at quantifying DNA adenine methylation in complex organisms

CRISPRa method helps discover genes that play a role in immune cell biology

Researchers receive $2,664,522 NIH award to improve long-term functionality of vascular grafts

CECR2 gene inhibition prevents triple-negative breast cancer from metastasizing, study shows

'Genetic scissors' can give rise to unforeseen heritable mutations

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Researchers discover why patients suffering with hypertension also have diabetes

C-Path and EJP RD collaborate to expand global rare disease research and drug development

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

ERGA aims to provide genomic data to inform research about Europe's biodiversity

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