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UMN researchers develop new way to study cancer cells in a 3D in vitro model

University of Minnesota researchers have developed a way to study cancer cells which could lead to new and improved treatment. They have developed a new way to study these cells in a 3D in vitro model (i.e. in a culture dish rather than in a human or animal).

12 Feb 2019

Watchful waiting in prostate cancer becoming more popular

In 2010, the US National Comprehensive Cancer Network guidelines suggested that patients with stable and low-risk prostate cancers could be managed with active surveillance or watchful waiting (AS/WW). AS/WW was considered to be a safe and effective alternative to aggressive surgery to remove the prostate and radiation therapy.

11 Feb 2019

Trojan Horse approach to cancer therapy shows promise

A new form of cancer fighting drug has been developed using the principles of the “Trojan Horse”.

11 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

Stereotactic body radiotherapy effective in treating men with low- or intermediate-risk prostate cancer

A new UCLA-led study shows that men with low- or intermediate-risk prostate cancer can safely undergo higher doses of radiation over a significantly shorter period of time and still have the same, successful outcomes as from a much longer course of treatment.

11 Feb 2019

New cancer drug that acts as ‘Trojan horse’ shows promise in patients with various cancers

A brand new type of cancer drug that acts as a 'Trojan horse' to get inside tumor cells has shown promise in patients with six different cancer types.

11 Feb 2019

Study identifies fatty acids as important fuel source for prostate tumors

An international multidisciplinary study initiated by Melbourne scientists has shown a link between prostate cancer and the uptake of fatty acids by cancer cells.

8 Feb 2019

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival.

8 Feb 2019

New prostate cancer prediction tool has unmatched accuracy

A team of researchers from the Icahn School of Medicine at Mount Sinai and Keck School of Medicine at the University of Southern California have developed a novel machine-learning framework that distinguishes between low- and high-risk prostate cancer with more precision than ever before.

7 Feb 2019

Physicians more likely to prescribe drugs of manufacturers who paid them money

In a study published in The Oncologist, physicians treating certain cancers who consistently received payments from a cancer drug's manufacturer were more likely to prescribe that drug over alternative treatments.

6 Feb 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

Study: Maternal age, body mass index, race affect hormone concentrations in pregnancy

Hormone concentrations during early fetal development -- that may affect the child's development and increase the mother's risk for breast and ovarian cancer years later -- are significantly affected by maternal age, body mass index and race rather than lifestyle, according to a Rutgers study.

5 Feb 2019

New study shows that larger prostate actually impedes tumor growth

For men older than about 60, an enlarged prostate means feeling the urge to make a pit stop way too often throughout the day.

5 Feb 2019

New path toward improving effectiveness of chemotherapy in breast, ovarian cancer

People who inherit a faulty copy of the so-called "breast cancer genes" BRCA1 and BRCA2 are at high risk of cancer. About 10 percent of breast cancer cases and 15 percent of ovarian cancers can be traced back to a flaw in one of these genes.

5 Feb 2019

Experts characterize normal electrical activity in prostate cancer cells in real time

Experts from the Universities of Bath and Seville have carried out a series of experiments with which, for the first time, they have been able to characterize the normal electrical activity in PC-3 prostate cancer cells in real time, with a resulting low-frequency electrical pattern between 0.1 and 10 Hertz.

5 Feb 2019

Study shows promise for future prostate cancer treatment

A new 'seek-and-destroy' gene therapeutic system could have the potential to treat prostate cancer in the future, after it halted the majority of tumors in laboratory models at the University of Strathclyde and the Beatson Institute.

4 Feb 2019

Study: Site of care could determine patients' access to palliative treatment

For patients at the end of life, palliative care can prolong survival and improve the quality of life for patients with a life-threatening illness and for their families.

4 Feb 2019

Cancer among Israeli men on the decline says report

According to a report from the Israel Cancer Association yesterday (3rd February 2019), there has been a significant fall in the number of Israeli men getting cancers over that last decade.

3 Feb 2019

Expediting HPLC Method Development in Pharmaceutical Analysis

In this interview, Michael Dong discusses stability-indicating methods such as UHPLC, in pharmaceutical analysis. At Pittcon, Michael will introduce a 3-pronged template approach to HPLC method development.

From Pittcon 30 Jan 2019

Community hospitals link arms with prestigious facilities to raise their profiles

After seven years of a vigorous fight, Jim Hart worried he was running out of options. Diagnosed with prostate cancer at age 60, Hart had undergone virtually every treatment — surgery, radiation and hormones — to eradicate it. But a blood test showed that his level of prostate-specific antigen, which should have been undetectable, kept rising ominously. And doctors couldn’t determine where the residual cancer was lurking.

29 Jan 2019