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VTT-originated Spectral Engines creates portable device for rapid screening of suspected drugs

Spectral Engines, a growth company that originated at VTT Technical Research Centre of Finland, is about to launch a portable drug screening device police patrols can use for rapid and cost-efficient on-site screening of suspected drugs.

30 Oct 2017

Continued Paracetamol exposure during pregnancy linked to ADHD in offspring

A new study has found that long term or continued use of acetaminophen or paracetamol during pregnancy is linked to a doubled risk of attention-deficit hyperactivity disorder (ADHD) in children. The study entitled, “Prenatal Exposure to Acetaminophen and Risk of ADHD” was published in the latest issue of the journal Pediatrics.

30 Oct 2017

Artificial beta cells could be first step to new treatment for diabetes

Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion.

30 Oct 2017

Researchers produce 3D map of molecular 'scaffold' known to play key role in cancers

Researchers have produced the first three-dimensional (3D) map of a molecular 'scaffold' called SgK223, known to play a critical role in the development and spread of aggressive breast, colon, and pancreatic cancers.

30 Oct 2017

New FAU study examines extent of ‘self-cyberbullying’ behavior among teens

Adolescents harming themselves with cuts, scratches or burns has gained a lot of attention over the years not just because of the physical damage and internal turmoil, but also because it has been linked to suicide. More recently, a new form of self-harm in youth has emerged and is cause for concern, warns a researcher and bullying expert from Florida Atlantic University.

30 Oct 2017

New gene drive approach helps pinpoint combination therapies against fungal pathogens

Candida albicans is a notorious human fungal pathogen that causes thrush and serious systemic infections. Opportunistic C. albicans fungi, which often live inconspicuously in the normal flora of human skin and gut, can switch from their harmless stealth mode to become aggressive pathogens, especially in people whose immune systems are already compromised by pre-existing diseases or harsh drug therapies.

30 Oct 2017

Study: Less than half of patients receive insurer's approval for prescription of cholesterol drugs

Less than half of patients received their insurer's approval for prescriptions of PCSK9 inhibitors, according to new research in the American Heart Association's journal Circulation.

30 Oct 2017

Novartis PARADIGMS study shows safety and efficacy of new treatment in pediatric MS patients

Novartis today announced full results from the positive Phase III PARADIGMS study, investigating the safety and efficacy of Gilenya (fingolimod) vs. interferon beta-1a, in children and adolescents (ages 10 to 17) with multiple sclerosis (MS).

30 Oct 2017

Experts issue new report with recommendations aimed at stemming opioid epidemic

A group of experts, led by researchers at the Johns Hopkins Bloomberg School of Public Health in collaboration with the Clinton Foundation, today issued a new report with comprehensive recommendations aimed at stemming the opioid epidemic, a spiraling crisis that kills on average 90 people a day in the U.S., and shows few signs of reversing.

28 Oct 2017

Cancer researchers make breakthrough in identifying genetic changes during immunotherapy

For some cancer patients, the road to remission and healing can have its share of speed bumps. That's particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which initially was effective against their tumors.

28 Oct 2017

CureVac begins phase I study to assess intratumoral application of RNAdjuvant technology in patients with solid tumors

CureVac AG, a fully-integrated biotechnology company pioneering mRNA-based drugs, today announced it has initiated a Phase I study assessing the intratumoral application of its novel RNAdjuvant technology in patients with superficial solid tumors that are easily accessible for repeated intratumoral injections. RNAdjuvant is designed to amplify the scope and quality of an immune response when used alone or in combination with other immune therapies.

28 Oct 2017

Sunovion announces results from Phase 3 clinical study of new drug in children, adolescents with bipolar depression

Sunovion Pharmaceuticals Inc. today announced post-hoc analysis results of a positive Phase 3 placebo-controlled clinical study, as well as interim data from a long-term open-label extension study evaluating Latuda (lurasidone HCI) in children and adolescents (10 to 17 years of age) with major depressive episodes associated with bipolar I disorder (bipolar depression).

28 Oct 2017

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Intriguing antitumor activity is found in a very promising class of natural compounds: cyclic depsipeptides, which have a challenging structure that makes their investigation difficult. Now, Chinese scientists have established the synthesis of a member compound, which is especially promising in killing pancreatic cancer stem cells.

28 Oct 2017

New findings offer promising druggable target to root out metastatic pancreatic cancer

Cancer of the pancreas is a deadly disease, with a median survival time of less than six months. Only one in 20 people with pancreatic cancer survives five years past the diagnosis. The reason is the cancer's insidiousness; tumor cells hide deep inside the body, betraying no symptoms until late in the disease, when the cancer has almost invariably spread to other organs.

28 Oct 2017

Breakthrough discovery could change the way of treating cholesterol

A breakthrough discovery by scientists at Houston Methodist could change the way we treat cholesterol. Researchers found new evidence that challenges a 40-year notion of how fast we eliminate it from our bodies.

28 Oct 2017

Novel consortium aims to create new paradigm of cancer drug discovery

Scientists from two U.S. national laboratories, industry and academia today launched an unprecedented effort to transform the way cancer drugs are discovered by creating an open and sharable platform that integrates high-performance computing, shared biological data from public and industry sources and emerging biotechnologies to dramatically accelerate the discovery of effective cancer therapies.

27 Oct 2017

New concise guide to pharmacology offers key information on major drug targets

The Concise Guide to PHARMACOLOGY 2017/18 is now available in the British Journal of Pharmacology. Published by Wiley on behalf of the British Pharmacological Society, the 440 page guide includes overviews of key properties for close to 1,700 human drug targets, identifies 3,500 ligands including more than 2,400 synthetic organic molecules and over 50 antibodies.

27 Oct 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Researchers at Linköping University in Sweden have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves.

27 Oct 2017

New targeted therapies help relieve symptoms of atopic dermatitis

If you think only infants suffer from eczema, think again. The uncomfortable, itchy rash that most people relate to babies and young children occurs frequently in adults.

27 Oct 2017

Drugs News and Research

VTT-originated Spectral Engines creates portable device for rapid screening of suspected drugs

Continued Paracetamol exposure during pregnancy linked to ADHD in offspring

Artificial beta cells could be first step to new treatment for diabetes

Researchers produce 3D map of molecular 'scaffold' known to play key role in cancers

New FAU study examines extent of ‘self-cyberbullying’ behavior among teens

New gene drive approach helps pinpoint combination therapies against fungal pathogens

Study: Less than half of patients receive insurer's approval for prescription of cholesterol drugs

Novartis PARADIGMS study shows safety and efficacy of new treatment in pediatric MS patients

Experts issue new report with recommendations aimed at stemming opioid epidemic

Cancer researchers make breakthrough in identifying genetic changes during immunotherapy

CureVac begins phase I study to assess intratumoral application of RNAdjuvant technology in patients with solid tumors

Sunovion announces results from Phase 3 clinical study of new drug in children, adolescents with bipolar depression

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

New findings offer promising druggable target to root out metastatic pancreatic cancer

Breakthrough discovery could change the way of treating cholesterol

Novel consortium aims to create new paradigm of cancer drug discovery

New concise guide to pharmacology offers key information on major drug targets

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

New targeted therapies help relieve symptoms of atopic dermatitis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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