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Discovery of key pathway, potential drug targets in autoinflammatory disease

Molecular biologists at Jefferson's Kimmel Cancer Center in Philadelphia have detailed the cascade of cellular events behind some potentially dangerous autoinflammatory diseases.

13 Nov 2007

Anti-inflammation molecule helps fight MS-like disease

An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis (MS). Neurology researchers led by Abdolmohamad Rostami, M.D., Ph.D., professor and chair of the Department of Neurology at Jefferson Medical College of Thomas Jefferson University and the Jefferson Hospital for Neuroscience in Philadelphia, have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease.

13 Nov 2007

FDA strengthens warnings for erythropoiesis-stimulating agents

The U.S. Food and Drug Administration has approved revised boxed warnings and other safety-related product labeling changes for erythropoiesis-stimulating agents (ESAs), which treat certain types of anemia.

13 Nov 2007

Factor key to severity of community-associated methicillin-resistant staph infections identified

Newly described proteins in drug-resistant strains of the Staphylococcus aureus bacterium attract and then destroy protective human white blood cells - a key process ensuring that S. aureus survives and causes severe disease, according to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

13 Nov 2007

New genetic schizophrenia link found

Schizophrenia is a debilitating psychiatric illness. Its cause is currently poorly understood, and there is no known cure.

13 Nov 2007

Could a new vaccine be the key to stopping Alzheimer's disease?

A new study from the Oklahoma Medical Research Foundation (OMRF) shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease.

13 Nov 2007

Abnormal immune cells may cause unprovoked idiopathic anaphylaxis

Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.

13 Nov 2007

Food, as opposed to specific nutrients, may be key to having a healthy diet

In a recent academic review, a University of Minnesota professor in the School of Public Health has concluded that food, as opposed to specific nutrients, may be key to having a healthy diet.

6 Nov 2007

Research sheds new light on how joints work

Mice that don't produce lubricin, a thin film of protein found in the cartilage of joints, showed early wear and higher friction in their joints, a new study led by Brown University researchers shows.

6 Nov 2007

Fat cells release a protein that aids insulin secretion from pancreatic beta cells

The body's fat cells help the pancreas do its job of secreting insulin, according to research at Washington University School of Medicine in St. Louis.

6 Nov 2007

Energy drinks raise blood pressure

Downing an “energy drink” may boost blood pressure as well as energy, researchers said in a small study presented at the American Heart Association's Scientific Sessions 2007.

6 Nov 2007

Prazosin curbs brain damage from post-traumatic stress disorder

A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.

6 Nov 2007

Potential new treatment for severe obesity

A team of researchers from the St Vincent's Campus in Sydney have developed a novel way to control the extreme weight loss, common in late stage cancer, which often speeds death.

6 Nov 2007

Chronic kidney disease common in U.S. - obesity, diabetes, hypertension and aging population contribute to increase

There is a high prevalence of chronic kidney disease in the United States, which has risen over the past decade, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

6 Nov 2007

Scientists in Australia discover how to switch hunger on and off

Scientists in Australia have found how to switch hunger on and off and they say their discovery could be used to stop weight loss in terminally ill patients or produce weight loss in the morbidly obese.

6 Nov 2007

New finding about the relationship between stress and cancer

One way environmental stress causes cancer is by reducing the activity level of an enzyme that causes cell death, researchers say.

6 Nov 2007

Modified Curcumin demonstrates even greater tumor suppressive properties

Curcumin, the yellowish component of turmeric that gives curry its flavor, has long been noted for its potential anti-cancer properties.

6 Nov 2007

Osteopontin-c is a good biomarker of breast cancer.

Researchers have identified a molecule that may be more accurate than existing biological signposts used to predict which breast cancers will develop into advanced forms of the disease.

6 Nov 2007

Chlorophyll breakdown in ripening apples and pears produces highly active antioxidants

Fall, the season of colors: Leaves turn red, yellow, and brown. The disappearance of the color green and the simultaneous appearance of these other colors are also signs of ripening fruit.

5 Nov 2007

First systemic therapy for fatal childhood disease - recessive dystrophic epidermolysis bullosa

University of Minnesota Children's Hospital, Fairview physicians have performed the first bone marrow and cord blood transplant to treat recessive dystrophic epidermolysis bullosa (RDEB).

5 Nov 2007