Immune System News and Research

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Worm eggs may heal ulcerative colitis: Research

A new study involving a man who swallowed worm eggs to relieve symptoms of ulcerative colitis sheds light on how worms promote healing in the intestine. The study, published today in Science Translational Medicine, also identifies potential targets for more conventional ways of treating colitis, an inflammatory bowel disease.

2 Dec 2010

Researchers identify blip in gene that causes JMP syndrome

UT Southwestern Medical Center researchers have identified a gene responsible for a rare disease that results in severe joint stiffness, muscle loss, anemia and panniculitis-induced lipodystrophy, or JMP syndrome.

2 Dec 2010

U.N. says PMTCT of HIV is achievable; efforts must target millions currently 'falling through the cracks'

A generation of babies could be born free of AIDS if the international community stepped up efforts to provide universal access to HIV prevention, treatment and social protection, the United Nations said on Tuesday, Reuters reports.

2 Dec 2010

Tolerx enters collaborative research agreement with Cancer Research Institute

Tolerx, Inc., a biopharmaceutical company developing novel therapies by modulating T cell activity, and the Cancer Vaccine Acceleration Fund (CVAF) a nonprofit program of the Cancer Research Institute established in partnership with the Ludwig Institute for Cancer Research today announced they entered into a collaborative research agreement to support development of Tolerx's drug candidate, TRX518, a monoclonal antibody designed to enhance the immune system by enabling T cells to more effectively attack cancer cells.

2 Dec 2010

Noncancerous cells from primary site appear to facilitate tumor growth: Study

The process of metastasis requires that cancer cells traveling from a primary tumor find a hospitable environment in which to implant themselves and grow. A new study from Massachusetts General Hospital (MGH) Cancer Center researchers finds that circulating tumor cells prepare this environment by bringing along from their original site noncancerous cells that support tumor growth. The report has been published online in PNAS Early Edition.

1 Dec 2010

Researchers show an oncolytic virus switches off cancer cell survival signal

Researchers from Boston University School of Medicine (BUSM) have identified a mechanism by which specific viruses acting as oncolytic agents can enter and kill cancer cells. This finding, which is currently featured in an online edition of the Journal of Virology, could help lead to the development of more targeted treatments against many types of cancer.

1 Dec 2010

PepTcell changes name to SEEK

PepTcell, a leading UK privately-owned drug-discovery group, today announced it is changing its name to SEEK.

1 Dec 2010

SPARTAC study examines ways to limit immune system damage in HIV infection

For most people in high-income countries HIV is considered a chronic illness which can be managed with medication. But the virus still causes extensive damage to the immune system, and treatment with antiretrovirals is a lifelong commitment. Once started, usually within three to five years following infection, the course of treatment needs to be strictly followed and taken for life.

1 Dec 2010

RCUK Academic Fellow to discuss microbial pathogens, immune system at Henry Wellcome Building

The Frank May Prize Lecture 2010 will be given by Dr Russell Wallis, speaking on microbial pathogens, and will be on Wednesday 1st December 2010, 5.30pm, in the Frank and Katherine May Lecture Theatre, Henry Wellcome Building (Lancaster Road), University of Leicester.

1 Dec 2010

Accelerator announces Series A Preferred Stock financing of Acylin

Accelerator Corporation, a privately held, venture capital backed biotechnology investment and development company, announced today the Series A Preferred Stock financing of Acylin Therapeutics, Inc. This is the eleventh company backed by Accelerator and its first investment in intellectual property developed by either Johns Hopkins University School of Medicine or The Wistar Institute, the co-owners of the underlying technology.

1 Dec 2010

Physician-scientists enroll patients with NSCLC cancer in MAGE-A3 Phase III trial

An experimental immunotherapy may someday become the newest weapon against lung cancer. Physician-scientists from Weill Cornell Medical College and Columbia University Medical Center are enrolling patients with non-small cell lung cancer (NSCLC) at NewYork-Presbyterian Hospital as part of an ongoing Phase III trial.

1 Dec 2010

Not all HIV viruses are bad for the immune system

Mayo Clinic researchers have shown why, in a minority of HIV patients, immune function improves despite a lack of response to standard anti-retroviral treatment. In these cases, researchers say, the virus has lost its ability to kill immune cells. The findings appear in the online journal PLoS Pathogens.

1 Dec 2010

Angptl4 protein deficiency could promote inflammatory response in people who consume high saturated fat

A new report in the December Cell Metabolism identifies a protein without which diets high in saturated fat lead to a massive inflammatory response that can prove fatal. The studies in mice suggest that deficiencies in this protective pathway could promote inflammation in those who regularly consume high levels of saturated fat.

1 Dec 2010

Bill & Melinda Gates Foundation awards $6M grant to NanoBio to develop intranasal vaccine for RSV

NanoBio Corporation announced today that it has received a $6M grant from the Bill & Melinda Gates Foundation to support the development of a safe and effective intranasal vaccine for Respiratory Syncytial Virus (RSV).

1 Dec 2010

PhRMA reports 100 new medicines and vaccines in development for HIV/AIDS

America's biopharmaceutical research companies are working on 100 new medicines and vaccines [video] to treat and prevent HIV/AIDS and related conditions, according to a new report from the Pharmaceutical Research and Manufacturers of America (PhRMA).

1 Dec 2010

Research on patients' immune system may lead to new diagnostic tool for HIV treatment

1 Dec 2010

Canadians at increased risk for flu complications not aware of all the facts

It starts with a headache, chills or that all-over-achy feeling. It comes on quickly, yet too many Canadians ignore the rapid onset of flu symptoms. But for the millions of Canadians at increased risk for developing serious complications from the flu, including people 65 and older, pregnant women and those with chronic medical conditions like chronic obstructive pulmonary disease (COPD), asthma, heart disease and diabetes, this 'laissez faire' attitude could be putting their health in jeopardy.

30 Nov 2010

Cytheris' combinational therapy demonstrates possible therapeutic strategy for PML

Cytheris SA, a clinical-stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced the publication of a case study report based on successful treatment of Progressive Multifocal Leukoencephalopathy (PML) with combination therapy consisting of two investigational agents, Cytheris' recombinant human interleukin-7 (CYT107) and CMX001, an investigational, oral broad-spectrum antiviral drug (Chimerix, Research Triangle Park, NC) in the Journal of Antimicrobial Chemotherapy.

30 Nov 2010

Fenwal's new Autopheresis-C software facilitates faster plasma-collection times

Fenwal, Inc., a global medical technology company focused on improving blood collection, separation, safety and availability, announced today that in a trial of its new Autopheresis-C® software, plasma-center professionals and donors reported faster plasma-collection times and an improved plasma-collection and donation experience. More than 90 percent of donors surveyed reported a decrease in their donation wait time. Donors who are more satisfied are more likely to donate regularly.

30 Nov 2010

GeoVax supports Bionor's Phase 2b trial of therapeutic HIV/AIDS vaccine

GeoVax Labs, Inc., an Atlanta-based, biopharmaceutical company developing human vaccines for HIV/AIDS (HIV-1, Human Immunodeficiency Virus), announced it was pleased to learn of the partial success observed in the recently completed Phase 2b trial of a therapeutic HIV/AIDS vaccine produced by Bionor Immuno AS of Oslo, Norway.

30 Nov 2010

Immune System News and Research

Worm eggs may heal ulcerative colitis: Research

Researchers identify blip in gene that causes JMP syndrome

U.N. says PMTCT of HIV is achievable; efforts must target millions currently 'falling through the cracks'

Tolerx enters collaborative research agreement with Cancer Research Institute

Noncancerous cells from primary site appear to facilitate tumor growth: Study

Researchers show an oncolytic virus switches off cancer cell survival signal

PepTcell changes name to SEEK

SPARTAC study examines ways to limit immune system damage in HIV infection

RCUK Academic Fellow to discuss microbial pathogens, immune system at Henry Wellcome Building

Accelerator announces Series A Preferred Stock financing of Acylin

Physician-scientists enroll patients with NSCLC cancer in MAGE-A3 Phase III trial

Not all HIV viruses are bad for the immune system

Angptl4 protein deficiency could promote inflammatory response in people who consume high saturated fat

Bill & Melinda Gates Foundation awards $6M grant to NanoBio to develop intranasal vaccine for RSV

PhRMA reports 100 new medicines and vaccines in development for HIV/AIDS

Research on patients' immune system may lead to new diagnostic tool for HIV treatment

Canadians at increased risk for flu complications not aware of all the facts

Cytheris' combinational therapy demonstrates possible therapeutic strategy for PML

Fenwal's new Autopheresis-C software facilitates faster plasma-collection times

GeoVax supports Bionor's Phase 2b trial of therapeutic HIV/AIDS vaccine

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