Inflammation News and Research

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Novel research points to promising relief target for chronic pain

By some accounts, chronic pain affects nearly 100 million Americans from such varied causes as arthritis, sciatica, cancer, diabetes. Most forms of pain result from identifiable causes which serve the "good" purpose in warning of a real physical problem that needs attention, or rest.

6 Jun 2006

Cigarette smoking and high cholesterol predict different forms of peripheral artery disease

Cigarette smoking and high cholesterol predict risk for some forms of peripheral artery disease (PAD), while diabetes predicts risk for other forms of the disease, researchers reported in a rapid access issue of Circulation: Journal of the American Heart Association.

6 Jun 2006

Gene variation linked to more severe Crohn's disease

Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease.

1 Jun 2006

Health disparities in juvenile rheumatoid arthritis

Juvenile rheumatoid arthritis (JRA), a group of autoimmune diseases involving chronic inflammation of the joints, can adversely affect health-related quality of life, often into adulthood.

31 May 2006

Cognitive behavioral therapy effective in treating irritable bowel syndrome

According to the latest research behavioral therapy was more effective in treating the symptoms of irritable bowel syndrome (IBS) than being on a waiting list for treatment.

29 May 2006

Largest U.S. hepatitis C trial yields treatment insights

Community-Based WIN-R Study Shows Significantly Better Outcomes with Weight-Based Dosing

24 May 2006

Hepatitis B virus prevalent among Asians in NY

Approximately 15% of Asians living in New York City are chronically infected with hepatitis B virus, according to a new study by New York University School of Medicine researchers and their colleagues.

23 May 2006

Arthritis drug wins approval for use in children with Crohn's disease

The Food and Drug Administration in the U.S. has given approval for the drug Remicade for use in children with active Crohn's disease(CD), a chronic and debilitating condition.

21 May 2006

New rheumatoid arthritis drugs may put patients at risk of infections and cancer

Anti-TNF (tumor necrosis factor) therapies are a tried and tested type of medication used for treating rheumatoid arthritis and the drugs provide benefit to many of thousands of patients worldwide.

21 May 2006

Newly discovered gene MCPIP may lead to treatments for preventing inflammation that cause heart disease

A newly discovered gene known as MCPIP could provide scientists with the key to developing treatments for preventing inflammation that can cause heart disease, University of Central Florida researchers have discovered.

17 May 2006

Plasminogen activator inhibitor type 2 may play role in infection and dry eye

Plasminogen Activator Inhibitor Type 2 (PAI-2), a protein found in various cell types including the skin, has been discovered in the tissue covering the eye and may have future clinical implications in various pathologies of the ocular surface such as eye infection or dry eye.

17 May 2006

Using probiotics is a safe and effective way to prevent asthma in children

In the first effort of its kind in the United States, researchers at the University of California, San Francisco have launched a study to determine whether giving active probiotic supplements to infants can delay or prevent asthma in children.

17 May 2006

Common genetic variation makes some people more susceptible to coronary heart disease

Caucasians who carry this polymorphism, named K55R, were at significantly higher risk of coronary heart disease, independent of other risk factors, like cigarette smoking, diabetes, and hypertension.

16 May 2006

Study holds promise for malarial susceptibility test

Cell and animal studies conducted jointly by scientists at Johns Hopkins, Yale and other institutions have uncovered at least one important contributor to the severe anemia that kills almost half of the 2 million people worldwide who die each year of malaria.

12 May 2006

15% of Asians living in New York City are chronically infected with hepatitis B virus

Chronic hepatitis B infection usually will lead to liver inflammation and can progress to cirrhosis and liver cancer. The reported infection rate is 35 times higher than the rate in the general U.S. population.

12 May 2006

K55R polymorphism gene variation linked to coronary heart disease

New research at the National Institute of Environmental Health Sciences, part of the National Institutes of Health, found that a common genetic variation makes some people more susceptible to coronary heart disease (CHD).

12 May 2006

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis

An imbalance in the lipid content of the liver appears to trigger the downward spiral that leads some with fatty liver disease to advance to full-blown liver failure, according to a new study in the May Cell Metabolism.

11 May 2006

Healthy habits and appropriate treatments help prevent stroke

Stroke is the third leading cause of death and a major source of disability in the United States. Every year about 700,000 people in the United States suffer a stroke, resulting in nearly 158,000 deaths.

10 May 2006

Inhaled corticosteroids can reduce breathing problems in children at high risk for asthma

Studies in older children and adults show that the most effective long-term control medicine for persistent asthma (symptoms more than two days a week or more than twice a month at night) is inhaled corticosteroids, which reduce airway swelling and help prevent asthma symptoms (e.g., asthma attacks).

10 May 2006

$Childhood arthritis increases the risk of fractures$

Childhood arthritis increases the risk of fractures

Childhood arthritis increases the risk of fractures, particularly during adolescence, according to a large study of British patient records. The researchers say that more targeted treatments promoting bone health would benefit patients with childhood-onset arthritis throughout their lifespan.

8 May 2006