Hormones News and Research

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Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics.

20 Feb 2019

New study establishes how stress favors breast cancer growth and spread

Cancer: The word alone evokes dread, anxiety, and fear. Accordingly, many women living with the disease and undergoing treatment experience chronic stress and depression.

19 Feb 2019

Hormone therapy during gender transition may increase risk for cardiovascular events

Patients receiving hormone therapy as part of their gender-transition treatment had an elevated risk for cardiovascular events, including strokes, heart attacks and blood clots, according to a study published in the American Heart Association's journal Circulation.

18 Feb 2019

Testosterone is not the only hormone needed for penis development

A new study has revealed that in addition to testosterone, the masculinization process involves a hormone called androsterone, which originates in other tissues.

15 Feb 2019

Human cells can change their original function to battle against diabetes

For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for diabetes patients.

14 Feb 2019

Study finds link between endocrine-disrupting chemicals and equine metabolic syndrome

Endocrine-disrupting chemicals in a horse's environment may play a role in the development of equine metabolic syndrome.

14 Feb 2019

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $12.5 million grant from the National Institute on Aging, part of the National Institutes of Health, for a five-year program called the U19 that consists of four multidisciplinary projects in aging biology.

14 Feb 2019

Researchers design new protocol to improve reproduction of ovine cattle

Researchers of the Veterinary Faculty of the CEU Cardenal Herrera University and the National Institute of Farming and Food Research and Technology have designed a new protocol to synchronize heats and ovulation periods to improve the reproduction of ovine cattle, which is based on the use of natural hormones.

13 Feb 2019

New rules requiring female athletes to lower testosterone levels are based on flawed data

New regulations requiring certain female athletes to medically lower their testosterone levels in order to compete internationally are based on "fatally flawed" data, according to new research led by the University of Colorado Boulder.

13 Feb 2019

Scientists discover new mechanism by which sleep supports the immune system

Getting enough sleep is vital to supporting our immune system in fighting off pathogens - so much is common knowledge. But what we don't know is how exactly sleep affects certain immune functions.

12 Feb 2019

Contraceptive pill may impair women's ability to recognize emotions

A new study suggests that a woman’s ability to read emotions may be negatively impacted by the contraceptive pill.

12 Feb 2019

Inhibiting tuberculosis-induced cell death with immunotherapy

Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy treatment, and side effects frequently lead to a discontinuation of treatment and high mortality rates.

12 Feb 2019

Alzheimer's disease protection from exercise hormone irisin

Irisin is found to be protective against Alzheimer’s disease finds a new study. The results of the new study were published in the journal Nature Medicine.

11 Feb 2019

Study reveals how exercise may protect against Alzheimer's disease

Athletes know a vigorous workout can release a flood of endorphins: "feel-good" hormones that boost mood. Now there's evidence that exercise produces another hormone that may improve memory and protect against Alzheimer's disease, according to a study co-led by Ottavio Arancio, MD, PhD, a researcher at Columbia University's Vagelos College of Physicians and Surgeons and Taub Institute for Research on Alzheimer's Disease and the Aging Brain.

11 Feb 2019

New research opens the way for tailored cancer drugs

New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer.

11 Feb 2019

Bariatric surgery changes the way our body senses food

How bariatric surgery helps people with obesity and diabetes is related to changes in the way the gut senses food and nutrients after the operation, researchers report February 5 in the journal Cell Reports.

8 Feb 2019

Phthalates may decrease fertility in female mice, study finds

A phthalate found in many plastic and personal care products may decrease fertility in female mice, a new study found.

8 Feb 2019

MUSC researchers examine the way estrogen affects drug addiction

Male rats have held steady as the focus of most addiction studies in the past. But as the field begins to take female rats into account, scientists see that drugs like methamphetamine affect the sexes differently, suggesting the basis for a change in addiction treatment.

7 Feb 2019

New acute porphyria treatment shows promising results in clinical study

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients.

7 Feb 2019

Study: Maternal age, body mass index, race affect hormone concentrations in pregnancy

Hormone concentrations during early fetal development -- that may affect the child's development and increase the mother's risk for breast and ovarian cancer years later -- are significantly affected by maternal age, body mass index and race rather than lifestyle, according to a Rutgers study.

5 Feb 2019