Neurodegenerative Diseases News and Research

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New study finds evidence that animals can judge time

Are you taking your time when feeding your pet? Fluffy and Fido are on to you -- and they can tell when you are dawdling.

24 Oct 2018

Researchers produce artificial antibody capable of blocking prions in the laboratory

Prion diseases affect the brain, causing neurodegenerative problems that always lead to death. They attracted attention in the late 1990s due to the "Mad Cow" scare.

22 Oct 2018

Study reveals connection between two proteins known to be hyperactive in cancer

A team of researchers at Baylor College of Medicine and Texas Children's Hospital has revealed a connection between mTORC1 and Src, two proteins known to be hyperactive in cancer.

20 Oct 2018

Prion strain diversity may be greater than previously thought

The first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought, according to a study published October 18 in the open-access journal PLOS Pathogens by Jason Bartz of Creighton University, and colleagues.

19 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Lack of sleep during adolescence and early adulthood accelerates Alzheimer’s disease-related tau pathology, finds a study of male and female mice published in JNeurosci.

17 Oct 2018

Down syndrome may hold important clues to onset of Alzheimer's disease

At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21.

17 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Vast majority of dementia cases may arise from spontaneous genetic errors

Only a small proportion of cases of dementia are thought to be inherited - the cause of the vast majority is unknown.

15 Oct 2018

'Eye scan' shows promise to diagnose central nervous system disorders

Partners from Austria – represented by Medical University of Vienna – Germany, France and the Netherlands are taking part in the EU "MOON" project (multimodal optical diagnostics for age-related diseases of the eye and central nervous system) to develop new techniques for early diagnosis of these diseases and successfully apply them in treatment and diagnosis.

12 Oct 2018

'Digital brain' recreates protein trafficking in the brain

Researchers have developed a digital 3D brain demonstrating how the toxic proteins involved in neurodegenerative diseases are transported through the brain.

12 Oct 2018

Insulin-binding protein in fruit flies could help tackle disease-carrying mosquitos

An insulin-binding protein in fruit flies could provide new opportunities for tackling disease-carrying mosquitos, such as malaria and yellow fever, scientists at the University of York have found.

12 Oct 2018

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Anthony Fitzpatrick, PhD, a Principal Investigator at Columbia's Zuckerman Institute and Columbia University Irving Medical Center, together with scientists from the Mayo Clinic and Boston Children's Hospital, has been awarded $11.3 million to map the three-dimensional structures of protein tangles that accumulate in the human brain.

11 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

Researchers discover previously unknown function of key component in the immune system

The complement proteins that circulate in our blood are an important part of our immune system. They help identify bacteria, viruses and other harmful organisms, making it easier for our white blood cells to find and neutralize dangerous microbes.

5 Oct 2018

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date.

4 Oct 2018

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

The Neurobiotechnology research team of the Universitat Jaume I in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, helping reverse brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity.

3 Oct 2018

Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

Alzheimer’s disease researchers makes significant breakthroughs

Researchers in Sweden and United Kingdom have made a breakthrough in Alzheimer’s disease research. They could soon be on the path to develop new drugs that could fight the disease more effectively.

26 Sep 2018

Neurodegenerative Diseases News and Research

New study finds evidence that animals can judge time

Researchers produce artificial antibody capable of blocking prions in the laboratory

Study reveals connection between two proteins known to be hyperactive in cancer

Prion strain diversity may be greater than previously thought

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Down syndrome may hold important clues to onset of Alzheimer's disease

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Vast majority of dementia cases may arise from spontaneous genetic errors

'Eye scan' shows promise to diagnose central nervous system disorders

'Digital brain' recreates protein trafficking in the brain

Insulin-binding protein in fruit flies could help tackle disease-carrying mosquitos

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Research team awarded $3.6 million to assess safety of genome editing

Researchers discover previously unknown function of key component in the immune system

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

Aggressive breast cancer hijacks normal protective physiological process to survive

Study finds disease-causing mutation in French-Canadians

Alzheimer’s disease researchers makes significant breakthroughs

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