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Intermuscular fat increases risk of heart disease independent of BMI

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to research published in the European Heart Journal today (Monday).

20 Jan 2025

New rabbit model provides insights into CF-related pancreatic endocrine pathology

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication.

17 Jan 2025

Researchers investigate myocarditis in preschoolers caused by parvovirus B19 outbreak

Researchers document the harmful consequences of myocarditis in preschool students, caused by a regional outbreak of parvovirus B19 in northern Greece.

17 Jan 2025

High out-of-pocket costs reduce participation in cardiac rehabilitation

Despite the success cardiac rehabilitation has shown at reducing heart-related deaths and hospital readmissions, higher out-of-pocket costs may prevent patients from participating in the program, a Michigan Medicine study suggests.

17 Jan 2025

NYU researchers lead groundbreaking effort to achieve whole eye transplants

Researchers from NYU Langone Health and NYU Grossman School of Medicine are part of a major undertaking that will bring together more than 40 scientists, doctors, and industry experts from around the country to make vision-restoring whole-eye transplants a reality.

17 Jan 2025

Brain neurons that respond to sugar and fat offer new insights into obesity control

The study uncovers hippocampal neurons that differentially respond to sugars and fats, suggesting new avenues for combating obesity through targeted therapies.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

Researchers discover a major driver of osteosarcoma

A major driver of the bone cancer osteosarcoma has been discovered by researchers from UCL, EMBL EBI and the Royal National Orthopaedic Hospital, providing insights that could help to predict cancer severity and how patients will respond to treatment.

16 Jan 2025

T-DM1 reduces long-term risk of death in HER2-positive breast cancer patients

In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared to trastuzumab alone, according to the final results of the phase 3 KATHERINE clinical trial led by researchers from the University of Pittsburgh and UPMC Hillman Cancer Center.

16 Jan 2025

Antihistamine shows promise for treating rare genetic liver disease

A common antihistamine may offer hope for patients with a rare genetic disease that can lead to severe liver damage and ultimately require transplantation, according to new research from Rutgers Health.

16 Jan 2025

Global Commission proposes new framework for obesity diagnosis and treatment

A global Commission, published in The Lancet Diabetes & Endocrinology and endorsed by 75 medical organizations around the world, presents a novel, nuanced approach to diagnose obesity, based on other measures of excess body fat in addition to body mass index (BMI), and objective signs and symptoms of ill health at the individual level.

15 Jan 2025

Dexter software platform reveals connection between early life trauma and immune disorders

University of Birmingham venture Dexter has demonstrated the power of its Dexter software platform in a study showing that people whose childhoods featured abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.

15 Jan 2025

Study reveals AI’s critical flaw in medical decision-making

Large language models excel at answering medical questions but fail to recognize their knowledge gaps, posing risks in clinical applications.

15 Jan 2025

New AI model offers hope for detecting brain cancer spread without surgery

Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients' cancer without aggressive surgery.

15 Jan 2025

Lifestyle support shows promise in reducing chronic back pain disability

Low back pain is a leading cause of disability worldwide with many treatments, such as medication, often failing to provide lasting relief.

15 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation.

15 Jan 2025

Study unravels the links between obesity and cancer

Obesity, recognized as a complex and growing health issue, is associated with an increased risk of various cancers. A comprehensive review provides insights into the mechanisms linking obesity to cancer risk and discusses potential clinical implications.

15 Jan 2025

Unveiling the hidden benefit of bariatric surgery

Welcoming a newborn is something many couples dream of doing, but it can get complicated when conceiving becomes a roadblock. Infertility affects one in six people, but obesity can also be a problem. When diet and exercise aren't enough to lose weight, bariatric surgery can become an option. Yet a new national survey by Orlando Health finds that 56% of Americans do not know that bariatric surgery is an effective way to improve fertility.

14 Jan 2025